다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
Neuroscience, v.101 no.3, 2000년, pp.547 - 561
Peña, F (Departamento de Neurociencias, Instituto de Fisiologı) , Tapia, R (́)
AI-Helper
AbstractInfusion of the K+ channel blocker 4-aminopyridine in the hippocampus induces the release of glutamate, as well as seizures and neurodegeneration. Since an imbalance between excitation and inhibition, as well as alterations of ion channels, may be involved in these effects of 4-aminopyridine...
Neurosci. Lett. Abele 115 195 1990 10.1016/0304-3940(90)90454-H Potassium channel activators abolish excitotoxicity in cultured hippocampal pyramidal neurons
J. Physiol. Alger 328 125 1982 10.1113/jphysiol.1982.sp014256 Pharmacological evidence for two kinds of GABA receptor on rat hippocampal pyramidal cells studied in vitro
Expl Brain Res. Arias 116 467 1997 10.1007/PL00005774 Neuronal damage and MAP2 changes induced by the glutamate transport inhibitor dihydrokainate and by kainate in rat hippocampus in vivo
J. Neurosci. Avoli 16 3912 1996 10.1523/JNEUROSCI.16-12-03912.1996 Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro
Brain Res. Baimbridge 245 223 1982 10.1016/0006-8993(82)90804-6 Immunohistochemical localization of calcium-binding protein in the cerebellum, hippocampal formation and olfactory bulb of the rat
Brain Res. Bull. Barna 51 241 2000 10.1016/S0361-9230(99)00224-5 Anticonvulsive effect of AMPA receptor antagonist GYKI 52466 on 4-aminopyridine-induced cortical activity in rat
Brain Res. Biggs 594 138 1992 10.1016/0006-8993(92)91038-G The effect of sodium valproate on extracellular GABA and other amino acids in the rat ventral hippocampus: an in vivo microdialysis study
Neurosci. Lett. Bijak 205 49 1996 10.1016/0304-3940(96)12368-5 Suppression by GABAB receptors of 4-aminopyridine-induced hyperactivity in guinea-pig neurons
Prog. Neurobiol. Bradford 47 477 1995 10.1016/0301-0082(95)00030-5 Glutamate, GABA and epilepsy
Brain Res. Bruckner 859 15 2000 10.1016/S0006-8993(99)02348-3 Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices
J. Membrane Biol. Cai 163 147 1998 10.1007/s002329900379 Single-channel characterization of the pharmacological properties of the K(Ca2+) channel of intermediate conductance in bovine aortic endothelial cells
Neuropharmacology Centonze 37 1063 1998 10.1016/S0028-3908(98)00081-1 Electrophysiology of the neuroprotective agent riluzole on striatal spiny neurons
Epilepsy Res. Chesnut 5 8 1990 10.1016/0920-1211(90)90061-Y Suppression of 4-aminopyridine-induced epileptogenesis by the GABAA agonist muscimol
Neuron Choi 1 623 1988 10.1016/0896-6273(88)90162-6 Glutamate neurotoxicity and diseases of the nervous system
Epilepsy Res. Coenen 21 89 1995 10.1016/0920-1211(95)00015-3 Effects of GABA-uptake inhibitor tiagabine on electroencephalogram, spike-wave discharges and behaviour of rats
Brain Res. Coleman 575 138 1992 10.1016/0006-8993(92)90433-A Protection against dendrotoxin-induced clonic seizures in mice by anticonvulsant drugs
Life Sci. Cramer 54 271 1994 10.1016/0024-3205(94)00845-0 Kainic acid and 4-aminopyridine seizure models in mice: evaluation of efficacy of antiepileptic agents and calcium antagonists
Brain Res. de Boer 253 153 1982 10.1016/0006-8993(82)90682-5 The effects of convulsant and anticonvulsant drugs on the release of radiolabeled GABA, glutamate, noradrenaline, serotonin and acetylcholine from rat cortical slices
Proc. natn. Acad. Sci. USA Dixon 94 4757 1997 10.1073/pnas.94.9.4757 The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates
Brain Res. Bull. Doczi 49 435 1999 10.1016/S0361-9230(99)00079-9 Effect of glutamate receptor antagonist (GYKI 52466) on 4-aminopyridine-induced seizure activity developed in rat cortical slices
Brain Res. Erdo 542 254 1991 10.1016/0006-8993(91)91575-L GABA accelerates excitotoxic cell death in cortical cultures: protection by blockers of GABA-gated chloride channels
Fariello R. G., Varasi M. and Smith M. C. (1995) Valproic acid mechanism of action. In Antiepileptic Drugs (eds Levy R. H., Mattson R. H. and Meldrum B. S.). Raven, New York.
J. Neurophysiol. Flores-Hernandez 72 2246 1994 10.1152/jn.1994.72.5.2246 Patterns of excitatory and inhibitory synaptic transmission in the rat neostriatum as revealed by 4-AP
Eur. J. Pharmac. Fragoso-Veloz 178 275 1990 10.1016/0014-2999(90)90106-G Seizures and wet-dog shakes induced by 4-aminopyridine, and their potentiation by nifedipine
Eur. J. Pharmac. Fragoso-Veloz 221 275 1992 10.1016/0014-2999(92)90713-E NMDA receptor antagonists protect against seizures and wet-dog shakes induced by 4-aminopyridine
Fromm G. H. (1992) Antiepileptic actions of carbamazepine. In Drugs for Control of Epilepsy: Actions on Neuronal Networks Involved in Seizure Disorders (eds Faingold C. L. and Fromm G. H.). CRC, Boca Raton, FL.
Fromm G. H. (1992) Antiepileptic actions of valproate. In Drugs for Control of Epilepsy: Actions on Neuronal Networks Involved in Seizure Disorders (eds Faingold C. L. and Fromm G. H.). CRC, Boca Raton, FL.
Epilepsy Res. Fueta 12 207 1992 10.1016/0920-1211(92)90075-5 Effects of antiepileptic drugs on 4-aminopyridine-induced epileptiform activity in young and adult rat hippocampus
Epilepsia Fueta 36 404 1995 10.1111/j.1528-1157.1995.tb01016.x Extracellular magnesium and anticonvulsant effects of valproate in young rat hippocampus
Eur. J. Pharmac. Gandolfo 160 173 1989 10.1016/0014-2999(89)90669-9 Ca2+ channel blockers prevent seizures induced by a class of K+ channel inhibitors
Brain Res. Gandolfo 495 189 1989 10.1016/0006-8993(89)91236-5 Subtypes of K+ channels differentiated by the effect of K+ channel openers upon K+ channel blocker-induced seizures
Eur. J. Pharmac. Gean 184 213 1990 10.1016/0014-2999(90)90612-A Epileptiform activity induced by 4-aminopyridine in rat amygdala neurons: the involvement of N-methyl-d-aspartate receptors
Epilepsy Res. Gonsalves 4 34 1989 10.1016/0920-1211(89)90056-9 Anticonvulsant activity of intracerebroventricularly administered glial GABA uptake inhibitors and other GABA mimetics in chemical seizure models
Brain Res. Goodman 706 328 1996 10.1016/0006-8993(95)01367-9 K+ channel openers protect hippocampal neurons against oxidative injury and amyloid β-peptide toxicity
Molec. Pharmac. Gribkoff 50 206 1996 Effects of channel modulators on cloned large-conductance calcium-activated potassium channels
Neuroscience Guyot 81 141 1997 10.1016/S0306-4522(97)00192-9 Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats
J. Neurochem. Herrera-Marschitz 66 1726 1996 10.1046/j.1471-4159.1996.66041726.x On the origin of extracellular glutamate levels monitored in the basal ganglia of the rat by in vivo microdialysis
Epilepsy Res. Hill 37 121 1999 10.1016/S0920-1211(99)00041-8 Effects of anticonvulsant lactams on in vitro seizures in the hippocampal slice preparation
Hippocampus Inglefield 5 460 1995 10.1002/hipo.450050508 Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus
Neuroscience Insel 35 31 1990 10.1016/0306-4522(90)90117-M The ontogeny of excitatory amino acid receptors in rat forebrain-I. N-Methyl-d-aspartate and quisqualate receptors
Epilepsy Res. Jackson 37 25 1999 10.1016/S0920-1211(99)00029-7 Activity-dependent enhancement of hyperpolarizing and depolarizing γ-aminobutyric acid (GABA) synaptic responses following inhibition of GABA uptake tiagabine
Molec. Pharmac. Kuo 51 1077 1997 10.1124/mol.51.6.1077 Carbamazepine inhibition of neuronal Na+ currents: quantitative distinction from phenytoin and possible therapeutic implications
J. Neurochem. Lada 70 617 1998 10.1046/j.1471-4159.1998.70020617.x Evidence for neuronal origin and metabotropic receptor-mediated regulation of extracellular glutamate and aspartate in rat striatum in vivo following electrical stimulation of the prefrontal cortex
J. Neurophysiol. Lamsa 78 2582 1997 10.1152/jn.1997.78.5.2582 Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine
J. Neurochem. Lauritzen 69 1570 1997 10.1046/j.1471-4159.1997.69041570.x The potassium channel opener (？)-cromakalim prevents glutamate-induced cell death in hippocampal neurons
Prog. Neurobiol. Loscher 58 31 1999 10.1016/S0301-0082(98)00075-6 Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action
Trends pharmac. Sci. Louvel 18 196 1997 10.1016/S0165-6147(97)01062-6 Therapeutic advances in amyotrophic lateral sclerosis
Neuron Luebke 11 895 1993 10.1016/0896-6273(93)90119-C Multiple calcium channel types control glutamatergic synaptic transmission in the hippocampus
J. Neurochem. Lukasiuk 74 2445 2000 10.1046/j.1471-4159.2000.0742445.x GABAA-mediated toxicity of hippocampal neurons in vitro
Int. Rev. Neurobiol. Lyden 40 233 1997 10.1016/S0074-7742(08)60722-9 GABA and neuroprotection
Macdonald R. L. (1995) Carbamazepine mechanism of action. In Antiepileptic Drugs (eds Levy R. H., Mattson R. H. and Meldrum B. S.). Raven, New York.
J. Neurochem. Massieu 64 2262 1995 10.1046/j.1471-4159.1995.64052262.x Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study
J. Neurochem. Massieu 69 1151 1997 10.1046/j.1471-4159.1997.69031151.x Glutamate uptake impairment and neuronal damage in young and aged rats in vivo
Neuropharmacology Mattia 33 1515 1994 10.1016/0028-3908(94)90124-4 Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice
Epilepsy Res. Meldrum 10 55 1991 10.1016/0920-1211(91)90095-W Excitotoxicity and epileptic brain damage
Epilepsia Meldrum 36 Suppl. 1 S30 1995 10.1111/j.1528-1157.1995.tb01649.x Neurotransmission in epilepsy
Science Michelson 253 1420 1991 10.1126/science.1654594 Excitatory synaptic responses mediated by GABAA receptors in the hippocampus
Neurochem. Int. Morales-Villagran 28 35 1996 10.1016/0197-0186(95)00064-F Preferential stimulation of glutamate release by 4-aminopyridine in rat striatum in vivo
Eur. J. Pharmac. Morales-Villagran 305 87 1996 10.1016/0014-2999(96)00157-4 Protection by NMDA receptor antagonists against seizures induced by intracerebral administration of 4-aminopyridine
Epilepsia Morimoto 38 966 1997 10.1111/j.1528-1157.1997.tb01478.x Antiepileptic effects of tiagabine, a selective GABA uptake inhibitor, in the rat kindling model of temporal lobe epilepsy
J. Neurophysiol. Motalli 82 638 1999 10.1152/jn.1999.82.2.638 GABAB receptor activation promotes seizure activity in the juvenile rat hippocampus
J. Neurophysiol. Muller 65 141 1991 10.1152/jn.1991.65.1.141 Picrotoxin- and 4-aminopyridine-induced activity in hilar neurons in the guinea pig hippocampal slice
Int. Rev. Neurobiol. Obrenovitch 40 109 1997 10.1016/S0074-7742(08)60718-7 Sodium and potassium channel modulators: their role in neuroprotection
Trends pharmac. Sci. Obrenovitch 19 9 1998 10.1016/S0165-6147(97)01124-3 Amyotrophic lateral sclerosis, excitotoxicity and riluzole
Prog. Neurobiol. Obrenovitch 51 39 1997 10.1016/S0301-0082(96)00049-4 Altered glutamatergic transmission in neurological disorders: from high extracellular glutamate to excessive synaptic efficacy
Eur. J. Pharmac. O’Neill 332 121 1997 10.1016/S0014-2999(97)01074-1 Effects of Ca2+ and Na+ channel inhibitors in vitro and in global cerebral ischaemia in vivo
Paxinos 1982 The Rat Brain in Stereotaxic Coordinates
J. Neurochem. Pena 72 2006 1999 10.1046/j.1471-4159.1999.0722006.x Relationships among seizures, extracellular amino acid changes, and neurodegeneration induced by 4-aminopyridine in rat hippocampus: a microdialysis and electroencephalographic study
J. Neurophysiol. Perrault 65 771 1991 10.1152/jn.1991.65.4.771 Physiology and pharmacology of epileptiform activity induced by 4-aminopyridine in rat hippocampal slices
Epilepsy Res. Pitkanen 33 67 1991 10.1016/S0920-1211(98)00074-6 Effects of vigabatrin treatment on status epilepticus-induced neuronal damage and mossy fiber sprouting in the rat hippocampus
Neuropharmacology Probert 36 1031 1997 10.1016/S0028-3908(97)00072-5 Sodium channel modulators prevent oxygen and glucose deprivation injury and glutamate release in rat neocortical cultures
Brain Res. Rev. Ragsdale 26 16 1998 10.1016/S0165-0173(97)00054-4 Sodium channels as molecular targets for antiepileptic drugs
Neurosci. Lett. Ravindran 176 209 1994 10.1016/0304-3940(94)90084-1 High extracellular GABA levels in hippocampus-as a mechanism of neuronal protection in cerebral ischemia in adrenalectomized gerbils
Eur. J. Pharmac. Rowley 294 541 1995 10.1016/0014-2999(95)00589-7 Differential effects of phenytoin and sodium valproate on seizure-induced changes in γ-aminobutyric acid and glutamate release in vivo
Neurochem. Int. Salazar 24 363 1994 10.1016/0197-0186(94)90114-7 Decrease of glutamate decarboxylase after in vivo cortical infusion of γ-aminobutyric acid
J. comp. Neurol. Sloviter 308 381 1991 10.1002/cne.903080306 Calcium-binding protein (calbindin-D28K) and parvalbumin immunocytochemistry in the normal and epileptic human hippocampus
Eur. J. Pharmac. Smith 273 259 1995 10.1016/0014-2999(94)00696-5 The γ-aminobutyric acid uptake inhibitor, tiagabine, is anticonvulsant in two animal models of reflex epilepsy
Science Staley 269 977 1995 10.1126/science.7638623 Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors
Expl Neurol. Stefani 147 115 1997 10.1006/exnr.1997.6554 Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies
Eur. J. Pharmac. Stutzmann 193 223 1991 10.1016/0014-2999(91)90040-W Riluzole prevents hyperexcitability produced by the mast cell degranulating peptide and dendrotoxin I in the rat
Epilepsia Swinyard 32 569 1991 10.1111/j.1528-1157.1991.tb04694.x Anticonvulsant profiles of the potent and orally active GABA uptake inhibitors SK&F 89976-A and SK&F 100300-A and four prototype antiepileptic drugs in mice and rats
Nature Takahashi 366 156 1993 10.1038/366156a0 Different types of calcium channels mediate central synaptic transmission
Neurochem. Int. Tapia 34 23 1999 10.1016/S0197-0186(98)00061-8 On the relationship between extracellular glutamate, hyperexcitation and neurodegeneration, in vivo
Brain Res. Tapia 250 291 1982 10.1016/0006-8993(82)90423-1 Effect of 4-aminopyridine on transmitter release in synaptosomes
Brain Res. Tapia 361 373 1985 10.1016/0006-8993(85)91307-1 Mechanism of the calcium-dependent stimulation of transmitter release by 4-aminopyridine in synaptosomes
Neuroscience Thesleff 5 1413 1980 10.1016/0306-4522(80)90002-0 Aminopyridines and synaptic transmission
J. Neurochem. Tibbs 53 1693 1989 10.1111/j.1471-4159.1989.tb09232.x Repetitive action potentials in isolated nerve terminals in the presence of 4-aminopyridine: effects on cytosolic free Ca2+ and glutamate release
Synapse Timmerman 27 242 1997 10.1002/(SICI)1098-2396(199711)27:3<242::AID-SYN9>3.0.CO;2-D Brain microdialysis of GABA and glutamate: what does it signify?
Brain Res. Versteeg 686 233 1995 10.1016/0006-8993(95)00515-R 4-Aminopyridine differentially affects the spontaneous release of radiolabelled transmitters from rat brain slices in vitro
Naunyn-Schmiedeberg’s Arch. Pharmac. Waldmeier 354 164 1996 Effect of carbamazepine, oxcarbazepine and lamotrigine on the increase in extracellular glutamate elicited by veratridine in rat cortex and striatum
Br. J. Pharmac. Watts 108 819 1993 10.1111/j.1476-5381.1993.tb12884.x Effects of carbamazepine and baclofen on 4-aminopyridine-induced epileptic activity in rat hippocampal slices
Epilepsy Res. Yamaguchi 11 9 1992 10.1016/0920-1211(92)90016-M Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice
Neurosci. Lett. Yamasaki 121 251 1991 10.1016/0304-3940(91)90697-R The possible involvement of tetrodotoxin-sensitive ion channels in ischemic neuronal damage in the rat hippocampus
Brain Res. Ye 753 1 1997 10.1016/S0006-8993(96)01473-4 Pre-synaptic effect of ATP-sensitive potassium channel opener diazoxide on rat substantia nigra pars reticulata neurons
Proc. natn. Acad. Sci. USA Ylinen 88 7650 1991 10.1073/pnas.88.17.7650 Enhanced GABAergic inhibition preserves hippocampal structure and function in a model of epilepsy
Epilepsy Res. Yonekawa 20 137 1995 10.1016/0920-1211(94)00077-A The effects of anticonvulsant agents on 4-aminopyridine induced epileptiform activity in rat hippocampus in vitro
Young A. B., Sakurai S. Y., Albin R. L., Makowiec R. and Penney J. B. (1991) Excitatory amino acid receptor distribution: quantitative autoradiographic studies. In Excitatory Amino Acids and Synaptic Transmission (eds Wheal H. V. and Thomson A. M.). Academic, San Diego.
Eur. J. Neurosci. Zhang 8 1432 1996 10.1111/j.1460-9568.1996.tb01605.x Expression of heat shock protein-70 and limbic seizure-induced neuronal death in the rat brain
Expl Brain Res. Zona 81 313 1990 10.1007/BF00228121 Effects induced by the antiepileptic drug valproic acid upon the ionic currents recorded in rat neocortical neurons in cell culture
Neuroscience Zona 85 931 1998 10.1016/S0306-4522(97)00604-0 Riluzole interacts with voltage-activated sodium and potassium currents in cultured rat cortical neurons
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.