[논문]Kinetic parameters of calcium currents in maturing acutely isolated CA1 cells

Ribeiro, Maria Alexandra; Costa, Pedro Freire

doi:10.1016/S0165-3806(00)00099-7

[해외논문] Kinetic parameters of calcium currents in maturing acutely isolated CA1 cells

Brain research, Developmental brain research, v.124 no.1/2, 2000년, pp.11 - 23

Ribeiro, Maria Alexandra (Departamento de Fisiologia, Faculdade de Ciê) , Costa, Pedro Freire (ncias Mé)

Abstract ▼ AI-Helper

AbstractCalcium currents were recorded in CA1 hippocampal cells from immature (P4–10) and older (P22–55) rats, using whole-cell voltage clamp techniques. Parameters defining the voltage-dependence of activation (τm) and inactivation (τh), steady-state inactivation and activation were determined at both stages of maturation. Current density increased with maturation. A transient low voltage activated (l.v.a.) current was found in P4–10 cells, but not in the older cells. At voltages less negative than −30 mV, current inactivation was best described by two exponentials (τhf,τhs); the ratio of the amplitudes of the two components changed with maturation, with a dominance of the faster component (τhf) in the younger cells. The voltage dependence of τhf followed a simple dependence model, decreased with increasing depolarization, in all cells at both stages of maturation. In P4–10 cells, τhs was voltage insensitive (range −25 to +30 mV); in P22–55 cells, the voltage dependence of τhs was found to be complex. Two current components were identified from the voltage dependence of the conductance in both groups. The first, more hyperpolarized component, the l.v.a. current found in P4–10 cells; this was absent in the older cells, in which we found a component with a different voltage dependence. The voltage dependence of the conductance of the second, more depolarized component did not differ in younger and older cells. In the course of maturation, the steady-state inactivation of the second component underwent a hyperpolarizing shift and a decrease in voltage sensitivity.

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참고문헌 (46)

J. Physiol. Aguayo 414 283 1989 10.1113/jphysiol.1989.sp017688 Post-natal development of K+ currents studied in isolated rat pineal cells

상세보기
J. Physiol. Akaike 412 181 1989 10.1113/jphysiol.1989.sp017610 Dihydropyridine-sensitive low-threshold calcium channels in isolated rat hypothalamic neurones

상세보기
J. Neurophysiol. Beck 68 2086 1992 10.1152/jn.1992.68.6.2086 Properties of two voltage-activated potassium currents in acutely isolated juvenile rat dentate gyrus granule cells

상세보기
J. Gen. Physiol. Bezanilla 70 549 1977 10.1085/jgp.70.5.549 Inactivation of the sodium current. I: sodium current experiments

상세보기
J. Physiol. Byerly 351 199 1984 10.1113/jphysiol.1984.sp015241 Rapidly activating hydrogen perfused neurones of the snail Lymnaea stagnalis

상세보기
J. Physiol. Carbone 386 547 1987 10.1113/jphysiol.1987.sp016551 Kinetics and selectivity of a low voltage-activated calcium current in chick and rat sensory neurone

상세보기
Dev. Brain Res. Costa 91 29 1996 10.1016/0165-3806(95)00159-X The kinetic parameters of sodium currents in maturing acutely isolated rat hippocampal CA1 neurones

상세보기
Dev. Brain Res. Costa 62 263 1991 10.1016/0165-3806(91)90174-H Afterpotential characteristics and firing patterns in maturing rat hippocampal CA1 neurones in in vitro slices

상세보기
NeuroReport Costa 3 555 1992 10.1097/00001756-199207000-00002 Slow and medium afterhyperpolarizations in maturing rat hippocampal neurones

상세보기
Dev. Brain Res. Costa 83 216 1994 10.1016/0165-3806(94)00140-5 Potassium currents in acutely isolated maturing rat hippocampal CA1 neurones

상세보기
Br. J. Pharmacol. Currie 106 593 1992 10.1111/j.1476-5381.1992.tb14381.x Calcium-activated currents in cultured neurones from rat dorsal root ganglia

상세보기
J. Physiol. Evans 378 437 1986 10.1113/jphysiol.1986.sp016229 Calcium-dependent chloride currents in isolated cells from rat lacrimal glands

상세보기
Neuroscience Fedulova 41 303 1991 10.1016/0306-4522(91)90219-E Ionic mechanisms of electrical excitability in rat sensory neurons during postnatal ontogenesis

상세보기
J. Physiol. Ficker 445 431 1992 10.1113/jphysiol.1992.sp018932 Slow and fast transient potassium currents in cultured hippocampal neurones

상세보기
J. Neurophysiol. Fisher 64 91 1990 10.1152/jn.1990.64.1.91 Properties and distribution of single voltage-gated calcium channels in adult hippocampal neurons

상세보기
J. Physiol. Hodgkin 117 500 1952 10.1113/jphysiol.1952.sp004764 A quantitative description of membrane current and its application to conduction and excitation in nerve

상세보기
Annu. Rev. Physiol. Huguenard 58 329 1996 10.1146/annurev.ph.58.030196.001553 Low-threshold calcium currents in central nervous system neurons

상세보기
Exp. Brain Res. Igelmund 109 21 1996 10.1007/BF00228623 Effects of T-type, L-type, N-type, P-type and Q-type calcium channel blockers on stimulus-induced pre- and postsynaptic calcium fluxes in rat hippocampal slices

상세보기
Pflugers Arch. Eur. J. Physiol. Johnson 429 14 1994 10.1007/BF02584025 Ca2+ channel Ca2+-dependent inactivation in a mammalian central neuron involves the cytoskeleton

상세보기
J. Physiol. Kay 427 27 1991 10.1113/jphysiol.1991.sp018581 Inactivation kinetics of calcium current of acutely dissociated CA1 pyramidal cells of the mature guinea-pig hippocampus

상세보기
J. Neurosci. Kay 6 10 2915 1986 10.1523/JNEUROSCI.06-10-02915.1986 Intracellular fluoride alters the kinetics properties of calcium currents facilitating the investigation of synaptic events in hippocampal neurons

상세보기
Dev. Brain Res. Kortekaas 101 139 1997 10.1016/S0165-3806(97)00059-X Development of HVA and LVA calcium currents in pyramidal CA1 neurons in the hippocampus of the rat

상세보기
Kostyuk 124 1992 Calcium Ions in Nerve Cell Function Development of calcium conductance during ontogenesis
J. Physiol. Kostyuk 270 545 1977 10.1113/jphysiol.1977.sp011968 Separation of sodium and calcium currents in the somatic membrane of mollusc neurones

상세보기
Nature Lee 265 751 1977 10.1038/265751a0 Trypsin inhibits the action of tetrodotoxin on neurones

상세보기
Mayer 355 1990 Calcium-dependent Chloride Currents in Vertebrate Central Neurons Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells
Neuron McCobb 2 1633 1989 10.1016/0896-6273(89)90052-4 Development alters the expression of calcium currents in chick limb motoneurons

상세보기
J. Physiol. McCormick 393 743 1987 10.1113/jphysiol.1987.sp016851 Post-natal development of electrophysiological properties of rat cerebral cortical pyramidal neurones

상세보기
J. Neurophysiol. Meyers 61 467 1989 10.1152/jn.1989.61.3.467 Whole-cell patch-clamp analysis of voltage-dependent calcium conductances in cultured embryonic rat hippocampal neurons

상세보기
J. Physiol. O’Dell 436 739 1991 10.1113/jphysiol.1991.sp018577 Single calcium channels in rat and guinea-pig hippocampal neurones

상세보기
Pflugers Arch. Oliver 434 772 1997 10.1007/s004240050464 Sodium current expression during postnatal development of rat outer hair cells

상세보기
J.Gen. Physiol. Pietrobon 94 1 1989 10.1085/jgp.94.1.1 Interactions of protons with single open L-type calcium channels. pH dependence of proton-induced current fluctuations with Cs+, K+, and Na+ as permeant ions

상세보기
Dev. Brain Res. Santos 108 13 1996 10.1016/S0165-3806(98)00025-X Sustained potassium currents in maturing CA1 hippocampal neurones

상세보기
Neuroreport Schmid 7 677 1996 10.1097/00001756-199601310-00070 Developmental regulation of voltage-activated Na+ and Ca2+ currents in rat retinal ganglion cells

상세보기
Dev. Brain Res. Schwartzkroin 2 469 1982 10.1016/0165-3806(81)90017-1 Development of rabbit hippocampus: physiology

상세보기
J. Pharmacol. and Exp. Ther. Takahashi 256 1 169 1991 Calcium antagonist effects on low-threshold (T-Type) calcium current in rat isolated hippocampal CA1 pyramidal neurons
Neurosci. Lett. Takahashi 103 29 1989 10.1016/0304-3940(89)90480-1 Comparison of low threshold calcium currents in the hippocampal CA1 neurons among the newborn, adult and aged rats

상세보기
Neurosci. Lett. Takahashi 104 229 1989 10.1016/0304-3940(89)90359-5 Hippocampal CA1 pyramidal cells of rats have four voltage-dependent calcium conductances

상세보기
J. Neurophysiol. Takahashi 65 148 1991 10.1152/jn.1991.65.1.148 Kinetic properties of T-type Ca2+ currents in isolated rat hippocampal Ca1 pyramidal neurons

상세보기
J. Physiol. Thompson 439 671 1991 10.1113/jphysiol.1991.sp018687 Development of calcium current subtypes in isolated rat hippocampal pyramidal cells

상세보기
Pfugers Arch. Toselli 421 59 1992 10.1007/BF00374734 Kinetic and pharmacological properties of high- and low-threshold calcium channels in primary cultures of rat hippocampal neurons

상세보기
Neuroscience Vreugdenhil 49 2 373 1992 10.1016/0306-4522(92)90103-9 Enhancement of calcium currents in rat hippocampal CA1 neurons induced by kindling epileptogenesis

상세보기
Pflugers Arch. Weber 429 820 1995 10.1007/BF00374806 Influence of extracelular Ca2+ on endogenous Cl？ channels in Xenopus oocytes

상세보기
Dev. Brain Res. Wilson 16 61 1984 10.1016/0165-3806(84)90063-4 A comparison of the postnatal development of post-activation potentiation in the neocortex and dentate gyrus of the rat

상세보기
J. Physiol. Wong 457 675 1992 10.1113/jphysiol.1992.sp019401 Different firing patterns generated in dendrites and somata of CA1 pyramidal neurones in guinea-pig hippocampus

상세보기
Am. J. Physiol. Xiong 265 C617 1993 10.1152/ajpcell.1993.265.3.C617 Changes in calcium channel current densities in rat colonic smooth muscle cells during development and aging

상세보기

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[해외논문] Kinetic parameters of calcium currents in maturing acutely isolated CA1 cells

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