[논문]The relationship between O-chain expression and colonisation ability of Helicobacter pylori in a mouse model

doi:10.1016/S0928-8244(00)00215-7

[해외논문] The relationship between O-chain expression and colonisation ability of Helicobacter pylori in a mouse model 원문보기

FEMS immunology and medical microbiology, v.29 no.4, 2000년, pp.263 - 270

Moran, Anthony P. (Department of Microbiology, National University of Ireland, Galway, Ireland) , Sturegård, Erik (Department of Infectious Diseases and Medical Microbiology, University of Lund, Lund, Sweden) , Sjunnesson, Hakan (Department of Infectious Diseases and Medical Microbiology, University of Lund, Lund, Sweden) , Wadström, Torkel (Department of Infectious Diseases and Medical Microbiology, University of Lund, Lund, Sweden) , Hynes, Sean O. (Department of Microbiology, National University of Ireland, Galway, Ireland)

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AbstractThe influence of lipopolysaccharide (LPS) O-polysaccharide chain production on the colonisation ability of Helicobacter pylori in four mouse models (NMRI, C57BL/6, CBA/Ca, and BALB/cA mice) was studied. H. pylori strains that produced smooth-form LPS (S-LPS) detectable in silver-stained electrophoretic gels colonised mice. In contrast, a laboratory-passaged strain G50 and the culture collection strain CCUG 17874 did not colonise mice; the former strain produced low amounts of O-chains only detectable in immunoblotting but not in silver-stained gels, whereas the latter produced rough-form LPS (R-LPS) without O-chains. Furthermore, a galE isogenic mutant, which produced R-LPS, did not colonise mice. However, after repeated broth culture, strains G50 and CCUG 17874 produced S-LPS detectable in silver-stained gels and were capable of colonising mice. Consistent with the production of O-chains, all colonising strains produced Lewis (Le) antigens, Lex and/or Ley. Except for low expression of Ley by non-colonising G50, reflecting low production of O-chains, all other non-colonising strains and the galE mutant lacked expression of Le antigens consistent with their production of R-LPS. Lectin typing of strains supported these findings, and also showed that lectin types did not differ before and after colonisation. The low level of O-chain production and Le antigen expression by the non-colonising G50 may not be sufficient to aid colonisation. Examination of protein profiles of H. pylori strains before inoculation showed that protein expression was not significantly different between colonising and non-colonising strains. These results show that S-LPS production with O-chain expression is required by H. pylori for colonisation in a number of mouse models and that care should be taken with inoculating H. pylori strains that loss of O-chains does not occur during subculturing.

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참고문헌 (45)

Clin. Microbiol. Rev. Dunn Helicobacter pylori 10 720 1997 10.1128/CMR.10.4.720

상세보기
Lancet Marshall Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration i 1311 1984 10.1016/S0140-6736(84)91816-6

상세보기
JAMA NIH Consensus Development Panel on Helicobacter pylori in peptic ulcer disease Helicobacter pylori in peptic ulcer disease 272 65 1994 10.1001/jama.1994.03520010077036

상세보기
Br. Med. J. Forman Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation 302 1302 1991 10.1136/bmj.302.6788.1302

상세보기
N. Engl. J. Med. Parsonnet Helicobacter pylori infection and gastric cancer lymphoma 330 1267 1994 10.1056/NEJM199405053301803

상세보기
FEMS Immunol. Med. Microbiol. Moran Cell surface characteristics of Helicobacter pylori 10 271 1995 10.1111/j.1574-695X.1995.tb00043.x

상세보기
FASEB J. Rietschel Bacterial endotoxin: molecular relationships of structure to activity and function 8 217 1994 10.1096/fasebj.8.2.8119492

상세보기
J. Toxicol. Toxin Rev. Moran Structurea€“bioactivity relationships of bacterial endotoxins 14 47 1995 10.3109/15569549509089968

상세보기
J. Bacteriol. Moran Compositional analysis of Helicobacter pylori rough-form lipopolysaccharides 174 1370 1992 10.1128/jb.174.4.1370-1377.1992

상세보기
J. Appl. Microbiol. Walsh Influence of medium composition on the growth and antigen expression of Helicobacter pylori 83 67 1997 10.1046/j.1365-2672.1997.00164.x

상세보기
[11] Moran, A.P., Walsh, E.J., In vitro production of endotoxin by the gastroduodenal pathogen Helicobacter pyloria€“ relevance to serotyping, Ir. J. Med. Sci., 162, (1993), 384
Carbohydr. Lett. Aspinall O antigen chains in the lipopolysaccharide of Helicobacter pylori NCTC 11637 1 151 1994
Biochemistry Aspinall Lipopolysaccharide of the Helicobacter pylori type strain NCTC 11637 (ATCC 43504): structure of the O antigen chain and core oligosaccharide regions 35 2489 1996 10.1021/bi951852s

상세보기
Biochemistry Aspinall Lipopolysaccharides of Helicobacter pylori strains P466 and MO19: structures of the O antigen and core oligosaccharide regions 35 2498 1996 10.1021/bi951853k

상세보기
J. Biol. Chem. Monteiro Simultaneous expression of type 1 and type 2 Lewis blood group antigens by Helicobacter pylori lipopolysaccharides. Molecular mimicry between H. pylori lipopolysaccharides and human gastric epithelial cell surface glycoforms 19 11533 1998 10.1074/jbc.273.19.11533

상세보기
Infect. Immun. Sherburne Helicobacter pylori expresses a complex surface carbohydrate, Lewis X 63 4564 1995 10.1128/IAI.63.12.4564-4568.1995

상세보기
J. Clin. Microbiol. Simoons-Smit Typing of Helicobacter pylori with monoclonal antibodies against Lewis antigens in lipopolysaccharide 34 2196 1996 10.1128/JCM.34.9.2196-2200.1996

상세보기
Infect. Immun. Wirth Expression of the human cell-surface glycoconjugates Lewis X and Lewis Y by Helicobacter pylori isolates is related to cagA status 64 4598 1996 10.1128/IAI.64.11.4598-4605.1996

상세보기
Cancer Res. Sakamoto Expression of Lewisa, Lewisb, Lewisx, Lewisy, sialyl-Lewisa, and sialyl-Lewisx blood group antigens in human gastric carcinoma and in normal gastric tissue 49 745 1989
Infect. Immun. Appelmelk Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity 64 2031 1996 10.1128/IAI.64.6.2031-2040.1996

상세보기
J. Endotoxin Res. Moran Molecular mimicry of host structures by lipopolysaccharides of Campylobacter and Helicobacter spp.: implications in pathogenesis 3 521 1996 10.1177/096805199600300611

상세보기
Trends Microbiol. Appelmelk Molecular mimicry between Helicobacter pylori and the host 5 70 1997 10.1016/S0966-842X(96)10084-6

상세보기
Immunol. Today Appelmelk Bugs on trial: the case of Helicobacter pylori and autoimmunity 19 296 1998 10.1016/S0167-5699(98)01281-X

상세보기
FEMS Immunol. Med. Microbiol. Marshall Lack of a relationship between Lewis antigen expression and cagA, CagA, vacA and VacA status of Irish Helicobacter pylori isolates 24 79 1999 10.1111/j.1574-695X.1999.tb01268.x

상세보기
Scand. J. Gastroenterol. Moran Pathogenic properties of Helicobacter pylori 31 Suppl. 215 22 1996 10.3109/00365529609094530

상세보기
Gastroenterology Lee A standardised mouse model of Helicobacter pylori infection: introducing the Sydney strain 112 1386 1997 10.1016/S0016-5085(97)70155-0

상세보기
Microb. Ecol. Health Dis. Wang RAPD-PCR, histopathological and serological analysis of four mouse strains infected with multiple strains of Helicobacter pylori 10 148 1998
Science Marchetti Development of a mouse model of Helicobacter pylori infection that mimics human disease 267 1655 1995 10.1126/science.7886456

상세보기
Infect. Immun. Xiang Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin 63 94 1995 10.1128/IAI.63.1.94-98.1995

상세보기
Curr. Microbiol. Kwon The effect of galE gene inactivation on lipopolysaccharide profile of Helicobacter pylori 37 144 1998 10.1007/s002849900354

상세보기
[31] Soltesz, V., SchalAⓒn, C. and MA￥rdh, P.A. (1988) New selective medium for Campylobacter pylori. In: Proc. of the Fourth International Workshop on Campylobacter Infections (Kaijser, B. and Falsen, E., Eds.), pp. 433a€“436. University of Gothenburg, Gothenburg.
Curr. Microbiol. Soltesz Serum-free liquid medium for Neisseria gonorrhoeae 4 45 1980 10.1007/BF02602891

상세보기
J. Bacteriol. Hitchcock Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels 154 269 1983 10.1128/JB.154.1.269-277.1983

상세보기
Nature Laemmli Cleavage of structural proteins during the assembly of the head bacteriophage T4 227 680 1970 10.1038/227680a0

상세보기
Anal. Biochem. Tsai A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels 119 115 1982 10.1016/0003-2697(82)90673-X

상세보기
J. Clin. Microbiol. Hynes Differentiation of Helicobacter pylori isolates based on lectin binding of cell extracts in an agglutination assay 37 1994 1999 10.1128/JCM.37.6.1994-1998.1999

상세보기
[37] Hynes, S.O., Sjunnesson, H., SturegA￥rd, E., WadstrA¶m, T. and Moran, A.P. (1999) A relationship between the expression of high molecular weight lipopolysaccharide by Helicobacter pylori and colonizing ability in mice. In: Abstracts of the 10th International Workshop on Campylobacter, Helicobacter and Related Organisms (Mobley, H.L.T., Nachamkin, I. and McGee, D., Eds.), p. 158. University of Maryland, Baltimore, MD.
FEMS Immunol. Med. Microbiol. Janvier Phenotypic changes of Helicobacter pylori components during an experimental infection in mice 24 27 1999 10.1111/j.1574-695X.1999.tb01261.x

상세보기
Gastroenterology Taylor Lack of correlation between Lewis antigen expression by Helicobacter pylori and gastric epithelial cells in infected patients 115 1113 1998 10.1016/S0016-5085(98)70082-4

상세보기
[40] Edwards, N.J., Monteiro, M., Walsh, E., Moran, A., Roberts, I.S. and High, N.J. (1999) The role of the lipopolysaccharide in adhesion of Helicobacter pylori. In: Abstracts of the 10th International Workshop on Campylobacter, Helicobacter and Related Organisms (Mobley, H.L.T., Nachamkin, I. and McGee, D., Eds.), p. 148. University of Maryland, Baltimore, MD.
Mol. Microbiol. Edwards Lewis X structures in the O antigen side-chain promote adhesion of Helicobacter pylori to the gastric epithelium 35 1530 2000 10.1046/j.1365-2958.2000.01823.x

상세보기
[42] Campbell, B.J., Rogerson, K.A., Rhodes, J.M., Adherence of Helicobacter pylori to human gastric epithelium mediated by an epithelial cell-surface Lewisx carbohydrate-binding protein, Gastroenterology, 116, (1999), A131
Proc. Natl. Acad. Sci. USA Falk An in vitro adherence assay reveals that Helicobacter pylori exhibits cell lineage-specific tropism in the human gastric epithelium 90 2035 1993 10.1073/pnas.90.5.2035

상세보기
Science Ilver Helicobacter pylori adhesin binding fucosylated histo blood group antigens revealed by retagging 279 373 1998 10.1126/science.279.5349.373

상세보기
Mol. Microbiol. Odenbreit Genetic and functional analysis of the alpAB gene locus essential for adhesion of Helicobacter pylori to human gastric tissue 31 1537 1999 10.1046/j.1365-2958.1999.01300.x

상세보기

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[해외논문] The relationship between O-chain expression and colonisation ability of Helicobacter pylori in a mouse model 원문보기

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