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Bioorganic & medicinal chemistry letters, v.10 no.24, 2000년, pp.2807 - 2810
Nakamura, Masayuki (Kobe Creative Center, Research Division of Senju Pharmaceutical Co., Ltd, 1-5-4 Murotani, Nishiku, Kobe 651-2241, Japan) , Inoue, Jun (Kobe Creative Center, Research Division of Senju Pharmaceutical Co., Ltd, 1-5-4 Murotani, Nishiku, Kobe 651-2241, Japan) , Yamada, Takashi (Department of Chemistry, Faculty of Science, Konan University, 8-9-1 Okamoto, Nadaku, Kobe 658-8501, Japan)
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AbstractA 100-member combinatorial library of α-ketoamides, which was designed to search potent cysteine protease inhibitors, was generated by a parallel solution-phase synthesis. A two-step one-pot synthesis, in which the Ugi reaction followed by pyridinium dichromate (PDC) oxidation was emp...
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