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[해외논문] Glycosylation of the calcitonin receptor-like receptor at Asn60 or Asn112 is important for cell surface expression

FEBS letters, v.486 no.3, 2000년, pp.320 - 324  

Bühlmann, Nicole (Research Laboratory for Calcium Metabolism, Departments of Orthopaedic Surgery and Medicine, University of Zurich, Klinik Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland) ,  Aldecoa, Amaya (Research Laboratory for Calcium Metabolism, Departments of Orthopaedic Surgery and Medicine, University of Zurich, Klinik Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland) ,  Leuthäuser, Kerstin (Research Laboratory for Calcium Metabolism, Departments of Orthopaedic Surgery and Medicine, University of Zurich, Klinik Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland) ,  Gujer, Remo (Research Laboratory for Calcium Metabolism, Departments of Orthopaedic Surgery and Medicine, University of Zurich, Klinik Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland) ,  Muff, Roman (Research Laboratory for Calcium Metabolism, Departments of Orthopaedic Surgery and Medicine, University of Zurich, Klinik Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland) ,  Fischer, Jan A (Research Laboratory for Calcium Metabolism, Departments of Orthopaedic Surgery and Medicine, University of Zurich,) ,  Born, Walter

Abstract AI-Helper 아이콘AI-Helper

AbstractThe human calcitonin (CT) receptor-like receptor (hCRLR) of the B family of G protein-coupled receptors is N-glycosylated and associates with receptor-activity-modifying proteins for functional interaction with CT gene-related peptide (CGRP) or adrenomedullin (ADM), respectively. Three putat...

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참고문헌 (16)

  1. Chang, C.-P., Pearse, R.V., O'Connell, S., Rosenfeld, M.G.. Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain. Neuron, vol.11, no.6, 1187-1195.

  2. Fluhmann, B., Muff, R., Hunziker, W., Fischer, J.A., Born, W.. A Human Orphan Calcitonin Receptor-like Structure. Biochemical and biophysical research communications, vol.206, no.1, 341-347.

  3. McLatchie, Linda M., Fraser, Neil J., Main, Martin J., Wise, Alan, Brown, Jason, Thompson, Nicola, Solari, Roberto, Lee, Melanie G., Foord, Steven M.. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature, vol.393, no.6683, 333-339.

  4. Bühlmann, Nicole, Leuthäuser, Kerstin, Muff, Roman, Fischer, Jan A., Born, Walter. A Receptor Activity Modifying Protein (RAMP)2-Dependent Adrenomedullin Receptor Is a Calcitonin Gene-Related Peptide Receptor when Coexpressed with Human RAMP1*. Endocrinology, vol.140, no.6, 2883-2890.

  5. 10.1210/endo.140.6.6930 

  6. Wimalawansa, Sunil J.. Amylin, Calcitonin Gene-Related Peptide, Calcitonin, and Adrenomedullin: A Peptide Superfamily. Critical reviews in neurobiology, vol.11, no.2, 167-239.

  7. Brain, S. D., Williams, T. J., Tippins, J. R., Morris, H. R., MacIntyre, I.. Calcitonin gene-related peptide is a potent vasodilator. Nature, vol.313, no.5997, 54-56.

  8. Nuki, C., Kawasaki, H., Kitamura, K., Takenaga, M., Kangawa, K., Eto, T., Wada, A.. Vasodilator Effect of Adrenomedullin and Calcitonin Gene-Related Peptide Receptors in Rat Mesenteric Vascular Beds. Biochemical and biophysical research communications, vol.196, no.1, 245-251.

  9. Aldecoa, Amaya, Gujer, Remo, Fischer, Jan A, Born, Walter. Mammalian calcitonin receptor-like receptor/receptor activity modifying protein complexes define calcitonin gene-related peptide and adrenomedullin receptors in Drosophila Schneider 2 cells. FEBS letters, vol.471, no.2, 156-160.

  10. Couvineau, A., Fabre, C., Gaudin, P., Maoret, J.-J., Laburthe, M.. Mutagenesis of N-Glycosylation Sites in the Human Vasoactive Intestinal Peptide 1 Receptor. Evidence That Asparagine 58 or 69 Is Crucial for Correct Delivery of the Receptor to Plasma Membrane. Biochemistry, vol.35, no.6, 1745-1752.

  11. Pang, Ronald Ting-Kai, Ng, Samuel Sai-Ming, Cheng, Christopher Hon-Ki, Holtmann, Martin H., Miller, Laurence J., Chow, Billy Kwok-Chong. Role of N-Linked Glycosylation on the Function and Expression of the Human Secretin Receptor. Endocrinology, vol.140, no.11, 5102-5111.

  12. Ho, H. H., Gilbert, M. T., Nussenzveig, D. R., Gershengorn, M. C.. Glycosylation Is Important for Binding to Human Calcitonin Receptors. Biochemistry, vol.38, no.6, 1866-1872.

  13. 10.1021/bi962111 

  14. Strategies Padgett K.A 58 9 1996 

  15. Zimmermann, Urs, Fischer, Jan A., Frei, Karl, Fischer, Andreas H., Reinscheid, Rainer K., Muff, Roman. Identification of adrenomedullin receptors in cultured rat astrocytes and in neuroblastboma × glioma hybrid cells (NG108-15). Brain research, vol.724, no.2, 238-245.

  16. Elbein, A D. Inhibitors of the Biosynthesis and Processing of N-Linked Oligosaccharide Chains. Annual review of biochemistry, vol.56, 497-534.

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