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[해외논문] Reduction of obesity, as induced by leptin, reverses endothelial dysfunction in obese (Lepob) mice

Journal of applied physiology, v.89 no.6, 2000년, pp.2382 - 2390  

Winters, Bradford (Departments of Anesthesiology and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287) ,  Mo, Zhiping (Departments of Anesthesiology and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287) ,  Brooks-Asplund, Esther (Departments of Anesthesiology and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287) ,  Kim, Soonyul (Departments of Anesthesiology and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287) ,  Shoukas, Artin (Departments of Anesthesiology and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287) ,  Li, Dechun (Departments of Anesthesiology and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287) ,  Nyhan, Daniel (Departments of Anesthesiology and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287) ,  Berkowitz, Dan E. (Departments of Anesthesiology and Biomedical Engineering, Johns Hopkins University)

Abstract AI-Helper 아이콘AI-Helper

Obesity is a major health care problem and is associated with significant cardiovascular morbidity. Leptin, a neuroendocrine hormone released by adipose tissue, is important in modulating obesity by signaling satiety and increasing metabolism. Moreover, leptin receptors are expressed on vascular en...

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