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American journal of human genetics, v.67 no.6, 2000년, pp.1422 - 1427
Hogenauer, C. , Santa Ana, C.A. , Porter, J.L. , Millard, M. , Gelfand, A. , Rosenblatt, R.L. , Prestidge, C.B. , Fordtran, J.S.
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To explain the very high frequency of cystic fibrosis (CF) mutations in most populations of European descent, it has been proposed that CF heterozygotes have a survival advantage when infected with Vibrio cholerae or Escherichia coli, the toxins of which induce diarrhea by stimulation of active inte...
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