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[해외논문] Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform‐specific, transgenic mice after global cerebral ischaemia

The European journal of neuroscience, v.12 no.12, 2000년, pp.4309 - 4317  

Horsburgh, Karen (1 Department of Neuropathology, University of Glasgow, Glasgow, UK 2 Wellcome Surgical Institute, University of Glasgow, Glasgow, UK 3 Glaxo Wellcome Research and Development, North Carolina, USA) ,  McCulloch, James (1 Department of Neuropathology, University of Glasgow, Glasgow, UK 2 Wellcome Surgical Institute, University of Glasgow, Glasgow, UK 3 Glaxo Wellcome Research and Development, North Carolina, USA) ,  Nilsen, Margaret (1 Department of Neuropathology, University of Glasgow, Glasgow, UK 2 Wellcome Surgical Institute, University of Glasgow, Glasgow, UK 3 Glaxo Wellcome Research and Development, North Carolina, USA) ,  Roses, Allen D. (1 Department of Neuropathology, University of Glasgow, Glasgow, UK 2 Wellcome Surgical Institute, University of Glasgow, Glasgow, UK 3 Glaxo Wellcome Research and Development, North Carolina, USA) ,  Nicoll, James A. R.

Abstract AI-Helper 아이콘AI-Helper

AbstractApolipoprotein E (apoE, protein; APOE, gene) is expressed as three isoforms in humans (E2, E3, E4). The APOE‐ε4 allele is associated with a poor outcome in patients after head injury of which ischaemic brain damage is a contributor of mortality and morbidity. The aim of the stu...

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참고문헌 (43)

  1. Alberts, MarkJ., Graffagnino, Carmen, McClenny, Cheryl, DeLong, David, Strittmatter, Warren, Saunders, AnnM., Roses, AllenD.. ApoE genotype and survival from intracerebral haemorrhage. The Lancet, vol.346, no.8974, 575-575.

  2. Bellosta, Stefano, Nathan, Britto P., Orth, Matthias, Dong, Li-Ming, Mahley, Robert W., Pitas, Robert E.. Stable Expression and Secretion of Apolipoproteins E3 and E4 in Mouse Neuroblastoma Cells Produces Differential Effects on Neurite Outgrowth. The Journal of biological chemistry, vol.270, no.45, 27063-27071.

  3. Bertrand, Philippe, Poirier, Judes, Oda, Tomiichiro, Finch, Caleb E., Pasinetti, Giulio Maria. Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease. Brain research. Molecular brain research, vol.33, no.1, 174-178.

  4. Buttini, Manuel, Orth, Matthias, Bellosta, Stefano, Akeefe, Hassibullah, Pitas, Robert E., Wyss-Coray, Tony, Mucke, Lennart, Mahley, Robert W.. Expression of Human Apolipoprotein E3 or E4 in the Brains ofApoe−/−Mice: Isoform-Specific Effects on Neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, vol.19, no.12, 4867-4880.

  5. Cambon, K, Davies, H.A, Stewart, M.G. Synaptic loss is accompanied by an increase in synaptic area in the dentate gyrus of aged human Apolipoprotein E4 transgenic mice. Neuroscience, vol.97, no.4, 685-692.

  6. Chen, Y, Lomnitski, L, Michaelson, D.M, Shohami, E. Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury. Neuroscience, vol.80, no.4, 1255-1262.

  7. Fleming, L.M., Weisgraber, K.H., Strittmatter, W.J., Troncoso, J.C., Johnson, G.V.W.. Differential Binding of Apolipoprotein E Isoforms to Tau and Other Cytoskeletal Proteins. Experimental neurology, vol.138, no.2, 252-260.

  8. Friedman, G., Froom, P., Sazbon, L., Grinblatt, I., Shochina, M., Tsenter, J., Babaey, S., Yehuda, A. Ben, Groswasser, Z.. Apolipoprotein E-ε4 genotype predicts a poor outcome in survivors of traumatic brain injury. Neurology, vol.52, no.2, 244-244.

  9. Fujii, Masazumi, Hara, Hideaki, Meng, Wei, Vonsattel, Jean Paul, Huang, Zhihong, Moskowitz, Michael A.. Strain-Related Differences in Susceptibility to Transient Forebrain Ischemia in SV-129 and C57Black/6 Mice. Stroke, vol.28, no.9, 1805-1811.

  10. Gill, R., Nordholm, L., Lodge, D.. The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischaemia model. Brain research, vol.580, no.1, 35-43.

  11. Graham, D I, Ford, I, Adams, J H, Doyle, D, Teasdale, G M, Lawrence, A E, McLellan, D R. Ischaemic brain damage is still common in fatal non-missile head injury.. Journal of neurology, neurosurgery, and psychiatry, vol.52, no.3, 346-350.

  12. Greenfields Neuropathology Graham D.I. 153 1992 

  13. Graham, D.I., Adams, J. Hume, Nicoll, J.A.R., Maxwell, W.L., Gennarelli, T.A.. The Nature, Distribution and Causes of Traumatic Brain Injury. Brain pathology, vol.5, no.4, 397-406.

  14. Hall, Edward D., Oostveen, Jo A., Dunn, Edwige, Carter, Donald B.. Increased Amyloid Protein Precursor and Apolipoprotein E Immunoreactivity in the Selectively Vulnerable Hippocampus Following Transient Forebrain Ischemia in Gerbils. Experimental neurology, vol.135, no.1, 17-27.

  15. Hayek, T., Oiknine, J., Brook, J.G., Aviram, M.. Increased Plasma and Lipoprotein Lipid Peroxidation in apo E-Deficient Mice. Biochemical and biophysical research communications, vol.201, no.3, 1567-1574.

  16. Horsburgh, K., Nicoll, J. A. R.. Selective alterations in the cellular distribution of apolipoprotein E immunoreactivity following transient cerebral ischaemia in the rat. Neuropathology and applied neurobiology, vol.22, no.4, 342-349.

  17. Alzheimer Res. Horsburgh K. 37 2 1996 Selective cellular alterations in amyloid precursor protein and apolipoprotein E following transient global ischaemia in the rat 

  18. Horsburgh, Karen, Fitzpatrick, Michael, Nilsen, Margaret, Nicoll, James A.R.. Marked alterations in the cellular localisation and levels of apolipoprotein E following acute subdural haematoma in rat. Brain research, vol.763, no.1, 103-110.

  19. Horsburgh, Karen, Kelly, Stephen, McCulloch, James, Higgins, Guy A., Roses, Allen D., R. Nicoll, James A.. Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia :. Neuroreport, vol.10, no.4, 837-841.

  20. 10.1097/00005072-199903000-00002 

  21. J. Cereb. Blood Flow Metab. Horsburgh K. 589 19 1 1999 Difference in susceptibility of MF1 mice compared to C57BL/6 mice following transient cerebral ischaemia 

  22. Horsburgh, Karen, McCulloch, James, Nilsen, Margaret, McCracken, Eileen, Large, Charles, Roses, Allen D., Nicoll, James A. R.. Intraventricular Infusion of Apolipoprotein E Ameliorates Acute Neuronal Damage after Global Cerebral Ischemia in Mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol.20, no.3, 458-462.

  23. JAMA Jordan B.D. 136 278 1997 10.1001/jama.1997.03550020068040 Apolipoprotein E ε‐4 associated with chronic traumatic brain injury in boxing 

  24. Laskowitz, D. T., Sheng, H., Bart, R. D., Joyner, K. A., Roses, A. D., Warner, D. S.. Apolipoprotein E-Deficient Mice Have Increased Susceptibility To Focal Cerebral Ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol.17, no.7, 753-758.

  25. Laskowitz, Daniel T., Horsburgh, Karen, Roses, Allen D.. Apolipoprotein E and the CNS Response to Injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol.18, no.5, 465-471.

  26. Mahley, RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science, vol.240, no.4852, 622-630.

  27. 10.1007/978-3-642-80109-9_6 

  28. McCarron, M. O., Muir, K. W., Weir, C. J., Dyker, A. G., Bone, I., Nicoll, J.A.R., Lees, K.R.. The Apolipoprotein E ε4 Allele and Outcome in Cerebrovascular Disease. Stroke, vol.29, no.9, 1882-1887.

  29. Miyata, Masaaki, Smith, Jonathan D.. Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and β-amyloid peptides. Nature genetics, vol.14, no.1, 55-61.

  30. Nathan, BP, Bellosta, S, Sanan, DA, Weisgraber, KH, Mahley, RW, Pitas, RE. Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro. Science, vol.264, no.5160, 850-852.

  31. Nellgård, B., Wieloch, T.. Postischemic Blockade of AMPA but Not NMDA Receptors Mitigates Neuronal Damage in the Rat Brain following Transient Severe Cerebral Ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol.12, no.1, 2-11.

  32. Nicoll, James A.R., Roberts, Gareth W., Graham, David I.. Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury. Nature medicine, vol.1, no.2, 135-137.

  33. Nicoll, James A. R., Burnett, Claire, Love, Seth, Graham, David I., Dewar, Debbie, Ironside, James W., Stewart, Janice, Vinters, Harry V.. High frequency of apolipoprotein E ϵ2 Allele in hemorrhage due to cerebral amyloid angiopathy. Annals of neurology, vol.41, no.6, 716-721.

  34. Park, C. K., Nehls, D. G., Graham, D. I., Teasdale, G. M., McCulloch, J.. The glutamate antagonist MK‐801 reduces focal ischemic brain damage in the rat. Annals of neurology, vol.24, no.4, 543-551.

  35. Poirier, J.. Apolipoprotein E in animal models of CNS injury and in alzheimer's disease. Trends in neurosciences, vol.17, no.12, 525-530.

  36. Saunders, A. M., Strittmatter, W. J., Schmechel, D., St. George-Hyslop, P. H., Pericak-Vance, M. A., Joo, S. H., Rosi, B. L., Gusella, J. F., Crapper-MacLachlan, D. R., Alberts, M. J., Hulette, C., Crain, B., Goldgaber, D., Roses, A. D.. Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease. Neurology, vol.43, no.8, 1467-1467.

  37. Sheng, Huaxin, Laskowitz, Daniel T., Bennett, Ellen, Schmechel, Donald E., Bart, Robert D., Saunders, Ann M., Pearlstein, Robert D., Roses, Allen D., Warner, David S.. Apolipoprotein E Isoform-Specific Differences in Outcome from Focal Ischemia in Transgenic Mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol.18, no.4, 361-366.

  38. Strittmatter, W J, Saunders, A M, Goedert, M, Weisgraber, K H, Dong, L M, Jakes, R, Huang, D Y, Pericak-Vance, M, Schmechel, D, Roses, A D. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease.. Proceedings of the National Academy of Sciences of the United States of America, vol.91, no.23, 11183-11186.

  39. Teasdale, Graham M, Nicoll, James AR, Murray, Gordon, Fiddes, Matilda. Association of apolipoprotein E polymorphism with outcome after head injury. The Lancet, vol.350, no.9084, 1069-1071.

  40. Teter, B., Xu, P.‐T., Gilbert, J. R., Roses, A. D., Galasko, D., Cole, G. M.. Human Apolipoprotein E Isoform‐Specific Differences in Neuronal Sprouting in Organotypic Hippocampal Culture. Journal of neurochemistry, vol.73, no.6, 2613-2616.

  41. Xu, Pu-Ting, Schmechel, Donald, Rothrock-Christian, Tracie, Burkhart, D.Scott, Qiu, Hui-Ling, Popko, Brian, Sullivan, Patrick, Maeda, Nobuyo, Saunders, Ann M., Roses, Allen D., Gilbert, John R.. Human Apolipoprotein E2, E3, and E4 Isoform-Specific Transgenic Mice: Human-like Pattern of GlialandNeuronal Immunoreactivity in Central Nervous System Not Observed in Wild-Type Mice. Neurobiology of disease, vol.3, no.3, 229-245.

  42. Xu, Pu-Ting, Gilbert, John R, Qiu, Hui-Ling, Rothrock-Christian, Tracie, Settles, Daniel L, Roses, Allen D, Schmechel, Donald E. Regionally specific neuronal expression of human APOE gene in transgenic mice. Neuroscience letters, vol.246, no.2, 65-68.

  43. Yang, Gongming, Kitagawa, Kazuo, Matsushita, Kohji, Mabuchi, Takuma, Yagita, Yoshiki, Yanagihara, Takehiko, Matsumoto, Masayasu. C57BL/6 strain is most susceptible to cerebral ischemia following bilateral common carotid occlusion among seven mouse strains: selective neuronal death in the murine transient forebrain ischemia. Brain research, vol.752, no.1, 209-218.

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