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[해외논문] Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins

Blood, v.96 no.10, 2000년, pp.3322 - 3328  

André, Patrick (From the Center for Blood Research and the Department of Pathology, Harvard Medical School, Boston, MA) ,  Denis, Cécile V. (the Roon Research Center for Arteriosclerosis and Thrombosis, The Scripps Research Institute, La Jolla, CA) ,  Ware, Jerry (and the Howard Hughes Medical Institute, Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA.) ,  Saffaripour, Simin (From the Center for Blood Research and the Department of Pathology, Harvard Medical School, Boston, MA) ,  Hynes, Richard O. (the Roon Research Center for Arteriosclerosis and Thrombosis, The Scripps Research Institute, La Jolla, CA) ,  Ruggeri, Zaverio M. (and the Howard Hughes Medical Institute, Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA.) ,  Wagner, Denisa D. (From the Center for Blood Research and the Department of Pathology, Harvard Medical School, Boston, MA)

Abstract AI-Helper 아이콘AI-Helper

With the use of intravital microscopy, a new type of platelet-endothelial interaction in mouse mesenteric venules at low shear (80-100 seconds−1) is described. Stimulation of these vessels with calcium ionophore A23187, a known secretagogue of Weibel-Palade bodies, induced immediate platelet ...

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