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[해외논문] Application of an Inter-Species Extrapolation Method for the Prediction of Drug Interactions between Propolis and Duloxetine in Humans 원문보기

International journal of molecular sciences, v.21 no.5, 2020년, pp.1862 -   

Ngo, Thi Lien (College of Pharmacy, Chungnam National University, Daejeon 34134, Korea) ,  Lee, Chung-Hee (ngolienvp@gmail.com (T.L.N.)) ,  Han, Nayoung (choonghii@o.cnu.ac.kr (C.-H.L.)) ,  Back, Hyun-Moon (hyyun@cnu.ac.kr (H.-Y.Y.)) ,  Rhee, Su-Jin (College of Pharmacy, Chungnam National University, Daejeon 34134, Korea) ,  Noh, Keumhan (ngolienvp@gmail.com (T.L.N.)) ,  Yun, Hwi-Yeol (choonghii@o.cnu.ac.kr (C.-H.L.)) ,  Kang, Wonku (hyyun@cnu.ac.kr (H.-Y.Y.)) ,  Chae, Jung-Woo (College of Pharmacy, Seoul National University, Gwanak-ro 1, Gwanakgu, Seoul 08826, Korea)

Abstract AI-Helper 아이콘AI-Helper

Duloxetine (DLX) is a potent drug investigated for the treatment of depression and urinary incontinence. DLX is extensively metabolized in the liver by two P450 isozymes, CYP2D6 and CYP1A2. Propolis (PPL) is one of the popular functional foods known to have effects on activities of CYPs, including C...

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참고문헌 (57)

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