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[해외논문] Epstein-Barr Virus Nuclear Protein 2 Has at Least Two N-Terminal Domains That Mediate Self-Association 원문보기

Journal of virology, v.75 no.5, 2001년, pp.2482 - 2487  

Harada, Shizuko (<) ,  Yalamanchili, Ramana (!--label omitted: 1-->) ,  Kieff, Elliott (Program in Virology and Departments of Medicine and Microbiology and Molecular Genetics, Channing Laboratory, Brigham and Women's Hospital and Harvard University, Boston, Massachusetts 02115)

Abstract AI-Helper 아이콘AI-Helper

ABSTRACTPrevious genetic and biochemical analyses have indicated that the Epstein-Barr virus EBNA-2 amino terminus is important for primary B-lymphocyte growth transformation and may be involved in self-association. We now report that EBNA-2 has at least two domains, amino acids 1 to 60 and 96 to 21...

참고문헌 (30)

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  3. Cohen, J I. A region of herpes simplex virus VP16 can substitute for a transforming domain of Epstein-Barr virus nuclear protein 2.. Proceedings of the National Academy of Sciences of the United States of America, vol.89, no.17, 8030-8034.

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  6. Dash, A B, Orrico, F C, Ness, S A. The EVES motif mediates both intermolecular and intramolecular regulation of c-Myb.. Genes & development, vol.10, no.15, 1858-1869.

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  8. Grossman, S R, Johannsen, E, Tong, X, Yalamanchili, R, Kieff, E. The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein.. Proceedings of the National Academy of Sciences of the United States of America, vol.91, no.16, 7568-7572.

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  10. Harada, Shizuko, Yalamanchili, Ramana, Kieff, Elliott. Residues 231 to 280 of the Epstein-Barr Virus Nuclear Protein 2 Are Not Essential for Primary B-Lymphocyte Growth Transformation. Journal of virology, vol.72, no.12, 9948-9954.

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  12. Jayachandra, Sukhanya, Low, Kenneth G., Thlick, Ai-En, Yu, Jin, Ling, Paul D., Chang, Yuan, Moore, Patrick S.. RETRACTED: Three unrelated viral transforming proteins (vIRF, EBNA2, and E1A) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors. Proceedings of the National Academy of Sciences of the United States of America, vol.96, no.20, 11566-11571.

  13. Jin, X W, Speck, S H. Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral BamHI C promoter. Journal of virology, vol.66, no.5, 2846-2852.

  14. Johannsen, E, Koh, E, Mosialos, G, Tong, X, Kieff, E, Grossman, S R. Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1. Journal of virology, vol.69, no.1, 253-262.

  15. Kaiser, Carmen, Laux, Gerhard, Eick, Dirk, Jochner, Nicola, Bornkamm, Georg W., Kempkes, Bettina. The Proto-Oncogene c- myc Is a Direct Target Gene of Epstein-Barr Virus Nuclear Antigen 2. Journal of virology, vol.73, no.5, 4481-4484.

  16. Kieff E. Epstein-Barr virus and its replication Fields virology 3rd ed. Fields B. N. Knipe D. M. Howley P. M. 1996 2343 2396 Lippincott-Raven Publishers Philadelphia Pa 

  17. Laux, G., Adam, B., Strobl, L.J., Moreau-Gachelin, F.. The Spi-1/PU.1 and Spi-B ets family transcription factors and the recombination signal binding protein RBP-J kappa interact with an Epstein-Barr virus nuclear antigen 2 responsive cis-element.. The EMBO journal, vol.13, no.23, 5624-5632.

  18. Leverson, Joel D, Koskinen, Päivi J, Orrico, Frank C, Rainio, Eeva-Marja, Jalkanen, Katriina J, Dash, Ajeeta B, Eisenman, Robert N, Ness, Scott A. Pim-1 Kinase and p100 Cooperate to Enhance c-Myb Activity. Molecular cell, vol.2, no.4, 417-425.

  19. Nitsche, F, Bell, A, Rickinson, A. Epstein-Barr virus leader protein enhances EBNA-2-mediated transactivation of latent membrane protein 1 expression: a role for the W1W2 repeat domain. Journal of virology, vol.71, no.9, 6619-6628.

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  22. Sjöblom, Anna, Yang, Weiwen, Palmqvist, Lars, Jansson, Ann, Rymo, Lars. An ATF/CRE Element Mediates both EBNA2-Dependent and EBNA2-Independent Activation of the Epstein-Barr Virus LMP1 Gene Promoter. Journal of virology, vol.72, no.2, 1365-1376.

  23. Tong, X, Drapkin, R, Reinberg, D, Kieff, E. The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2.. Proceedings of the National Academy of Sciences of the United States of America, vol.92, no.8, 3259-3263.

  24. Tong, Xiao, Drapkin, Ronny, Yalamanchili, Ramana, Mosialos, George, Kieff, Elliott. The Epstein-Barr Virus Nuclear Protein 2 Acidic Domain Forms a Complex with a Novel Cellular Coactivator That Can Interact with TFIIE. Molecular and cellular biology, vol.15, no.9, 4735-4744.

  25. Tong, X, Wang, F, Thut, C J, Kieff, E. The Epstein-Barr virus nuclear protein 2 acidic domain can interact with TFIIB, TAF40, and RPA70 but not with TATA-binding protein. Journal of virology, vol.69, no.1, 585-588.

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  27. Wang, Lian, Grossman, Steven R., Kieff, Elliott. Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter. Proceedings of the National Academy of Sciences of the United States of America, vol.97, no.1, 430-435.

  28. Yalamanchili, R, Harada, S, Kieff, E. The N-terminal half of EBNA2, except for seven prolines, is not essential for primary B-lymphocyte growth transformation. Journal of virology, vol.70, no.4, 2468-2473.

  29. Yalamanchili, Ramana, Tong, Xiao, Grossman, Steve, Johannsen, Eric, Mosialos, George, Kieff, Elliott. Genetic and Biochemical Evidence That EBNA 2 Interaction with a 63-kDa Cellular GTG-Binding Protein Is Essential for B Lymphocyte Growth Transformation by EBV. Virology, vol.204, no.2, 634-641.

  30. Zimber-Strobl, U., Strobl, L.J., Meitinger, C., Hinrichs, R., Sakai, T., Furukawa, T., Honjo, T., Bornkamm, G.W.. Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless.. The EMBO journal, vol.13, no.20, 4973-4982.

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