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NTIS 바로가기Journal of virology, v.75 no.5, 2001년, pp.2488 - 2492
Luo, Tianci (<) , Fredericksen, Brenda L. (!--label omitted: 1-->) , Hasumi, Keiji (Genetic Therapy Inc., Gaithersburg, Maryland 208791) , Endo, Akira , Garcia, J. Victor (<)
ABSTRACTOne well-characterized in vitro function of Nef is its ability to remove CD4, the human immunodeficiency virus (HIV) receptor, from the cell surface. Nef accomplishes this by accelerating the internalization and degradation of CD4. Current models propose that Nef promotes CD4 internalization...
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