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The egr‐1 promoter contains information for constitutive and inducible expression in transgenic mice
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, v.14 no.13, 2000년, pp.1870 - 1872
Tsai, Jo C. (Department of Molecular MedicineBeth Israel Deaconess Medical CenterBoston MA) , Liu, Lixin (Department of Molecular MedicineBeth Israel Deaconess Medical CenterBoston MA) , Cooley, Brian C. (Department of Orthopaedic SurgeryMedical College of WisconsinMilwaukee WI) , DiChiara, Maria R. (Department of MedicineStanford University School of MedicineStanford CA) , Topper, James N. (Department of MedicineStanford University School of MedicineStanford CA) , Aird, William C. (Department of Molecular MedicineBeth Israel Deaconess Medical CenterBoston MA)
Abstract
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Egr-1 is an immediate early gene that couples short-term changes in the extracellular milieu to long-term changes in gene expression. Under in vitro conditions, the Egr-1 gene is expressed in many cell types and is induced by a wide variety of extracellular signals. The mechanisms by which the Egr-1...
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