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Association between the serotonin 2A receptor gene and tardive dyskinesia in chronic schizophrenia 원문보기

Molecular psychiatry, v.6 no.2, 2001년, pp.225 - 229  

Segman, R H (Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah–) ,  Heresco-Levy, U (Hebrew University Medical Center, Jerusalem, Israel) ,  Finkel, B (Herzog Hospital, Jerusalem, Israel) ,  Goltser, T (Lev Hasharon Hospital, Pardessia, Israel) ,  Shalem, R (Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah–) ,  Schlafman, M (Hebrew University Medical Center, Jerusalem, Israel) ,  Dorevitch, A (Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah–) ,  Yakir, A (Hebrew University Medical Center, Jerusalem, Israel) ,  Greenberg, D (Kfar Shaul Hospital, Jerusalem, Israel) ,  Lerner, A (Talbieh Hospital, Jerusalem, Israel) ,  Lerer, B (Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah–)

Abstract AI-Helper 아이콘AI-Helper

Tardive dyskinesia (TD) is a long-term adverse effect of antipsychotic drugs that are dopamine D2 receptor blockers.1 Serotonin receptor antagonism has been proposed as a common mechanism contributing to the low extrapyramidal effects profile of atypical antipsychotic drugs.2 We examined the associa...

참고문헌 (46)

  1. Arch Gen Psychiatry JM Kane 37 473 1982 10.1001/archpsyc.1982.04290040069010 Kane JM, Smith JM . Tardive dyskinesia: prevalence and risk factors, 1959 to 1979 Arch Gen Psychiatry 1982 37: 473-481 

  2. Neuropsychopharmacology HY Meltzer 21 Suppl 2 106 1999 10.1016/S0893-133X(99)00046-9 Meltzer HY . The role of serotonin in antipsychotic drug action Neuropsychopharmacology 1999 21 Suppl 2: 106-115 

  3. Hum Mol Genet JT Waren 2 338 1993 10.1093/hmg/2.3.338 Waren JT, Peacock ML, Rodriguez LC, Fink JK . An Mspl polymorphism in the human serotonin receptor gene: detection by DGGE and RFLP analysis Hum Mol Genet 1993 2: 338 

  4. Biol Psychiatry N Ozaki 40 1267 1996 10.1016/0006-3223(95)00649-4 Ozaki N, Rosenthal NE, Pesonen U . Two naturally occurring amino acid substitutions of the 5-HT2A receptor: similar prevalence in patients with seasonal affective disorder and controls Biol Psychiatry 1996 40: 1267-1272 

  5. Lancet DA Collier 350 412 1997 10.1016/S0140-6736(05)64135-9 Collier DA, Arranz MJ, Li T, Mupita D, Brown N, Treasure J . Association between 5-HT2A gene promoter polymorphism and anorexia nervosa Lancet 1997 350: 412 

  6. Lancet J Williams 349 1221 1997 10.1016/S0140-6736(05)62413-0 Williams J, McGuffin P, Nothen M, Owen MJ . Meta-analysis of association between the 5-HT2a receptor T102C polymorphism and schizophrenia. EMASS Collaborative Group. European Multicentre Association Study of Schizophrenia [letter] Lancet 1997 349: 1221 

  7. Clin Genet RH Belmaker 19 353 1981 10.1111/j.1399-0004.1981.tb00725.x Belmaker RH, Bannet J, Brecher-Fried E . The effect of haloperidol feeding on dopamine receptor number in ten mouse strains Clin Genet 1981 19: 353-356 

  8. Pharm Biochem Behav H Rosengarten 3 633 1994 Rosengarten H, Schweitzter JW, Friedhoff AJ . Possible genetic factors underlying the pathophysiology of tardive dyskinesia Pharm Biochem Behav 1994 3: 633-667 

  9. Ann Clin Psychiatry JR Swartz 9 53 1997 10.3109/10401239709147773 Swartz JR, Burgoyne K, Smith M, Gadasally R, Ananth J, Ananth K . Tardive dyskinesia and ethnicity: review of the literature Ann Clin Psychiatry 1997 9: 53-59 

  10. Weinhold P, Wegner JT, Kane JM . Familial occurrence of tardive dyskinesia J Clin Psychiatry 42: 165-166 

  11. Mol Psychiatry R Segman 4 247 1999 10.1038/sj.mp.4000511 Segman R, Neeman T, Heresco-Levy U, Finkel B, Karagacev L, Schlafman M et al. Genotypic association between the dopamine D3 receptor gene and tardive dyskinesia in chronic schizophrenia Mol Psychiatry 1999 4: 247-253 

  12. Mol Psychiatry VM Steen 2 139 1997 10.1038/sj.mp.4000249 Steen VM, Llie R, McEwan T, McCreadie RG . Dopamine D3 receptor gene variant and susceptibility to tardive dyskinesia in schizophrenic patients Mol Psychiatry 1997 2: 139-145 

  13. Neuropsychopharmacology VS Basile 21 17 1999 10.1016/S0893-133X(98)00114-6 Basile VS, Masellis M, Badri F, Paterson AD, Meltzer HY, Lieberman JA et al. Association of the Mscl polymorphism of the dopamine D3 receptor gene with tardive dyskinesia in schizophrenia Neuropsychopharmacology 1999 21: 17-27 

  14. Int J Neuropsychopharmacol R Lovlie 3 61 2000 10.1017/S1461145700001796 Lovlie R, Daly AK, Blennerhassett R, Ferrier N, Steen VM . Homozygosity for Gly-9 variant of the dopamine D3 receptor and risk for tardive dyskinesia in schizophrenic patients Int J Neuropsychopharmacol 2000 3: 61-66 

  15. J Clin Psychiatry DE Casey 59 Suppl 3 31 1998 Casey DE . Effects of clozapine therapy in schizophrenic individuals at risk for tardive dyskinesia J Clin Psychiatry 1998 59 Suppl 3: 31-37 

  16. J Clin Psychiatry CA Tamminga 55 Suppl B 102 1994 Tamminga CA, Thaker GK, Moran M, Kakigi T, Gao XM . Clozapine in tardive dyskinesia: observations from human and animal model studies J Clin Psychiatry 1994 55 Suppl B: 102-106 

  17. J Clin Psychiatry WM Glazer 61 21 2000 Glazer WM . Expected incidence of tardive dyskinesia associated with atypical antipsychotics J Clin Psychiatry 2000 61: 21-26 

  18. Neurochem Res D Marazziti 22 753 1997 10.1023/A:1027366413289 Marazziti D, Rossi A, Palego L . [3H]ketanserin binding in human brain postmortem Neurochem Res 1997 22: 753-757 

  19. Life Sci CJ Schmidt 56 2209 1995 10.1016/0024-3205(95)00210-W Schmidt CJ, Sorensen SM, Kehne JH, Carr AA, Palfreyman MG . The role of 5-HT2A receptors in antipsychotic activity Life Sci 1995 56: 2209-2222 

  20. J Neural Transm I Kusumi 107 295 2000 10.1007/s007020050024 Kusumi I, Takahashi Y, Suzuki K, Kameda K, Koyama T . Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain J Neural Transm 2000 107: 295-302 

  21. Arch Gen Psychiatry R Rubovits 27 502 1972 10.1001/archpsyc.1972.01750280070012 Rubovits R, Klawans HL Jr . Implications of amphetamine induced stereotyped behavior as a model for tardive dyskinesia Arch Gen Psychiatry 1972 27: 502-507 

  22. Prog Neuropsychopharmacol Biol Psychiatry H Rosengarten 23 1389 1999 10.1016/S0278-5846(99)00073-1 Rosengarten H, Schweitzer JW, Friedhoff AJ . The effect of novel antipsychotics in rat oral dyskinesia Prog Neuropsychopharmacol Biol Psychiatry 1999 23: 1389-1404 

  23. Neuroreport VS Barwick 11 267 2000 10.1097/00001756-200002070-00009 Barwick VS, Jones DH, Richter JT, Hicks PB, Young KA . Subthalamic nucleus microinjections of 5-HT2 receptor antagonists suppress stereotypy in rats Neuroreport 2000 11: 267-270 

  24. J Neurochem RM Kostrzewa 70 889 1998 10.1046/j.1471-4159.1998.70030889.x Kostrzewa RM, Reader TA, Descarries L . Serotonin neural adaptations to ontogenetic loss of dopamine neurons in rat brain J Neurochem 1998 70: 889-898 

  25. Somat Cell Genet CL Hsieh 16 567 1990 10.1007/BF01233097 Hsieh CL, Bowcock AM, Farrer LA, Hebert JM, Huang KM, Cavalli-Sforza LL et al. The serotonin receptor subtype 2 locus HTR2 is on chromosome 13 near genes for estherase D and retinoblastoma and on mouse chromosome 14 Somat Cell Genet 1990 16: 567-574 

  26. Hum Genet J Erdmann 97 614 1996 10.1007/BF02281871 Erdmann J, Shimron-Abarbanell D, Rietschel M . Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: identification of two naturally occurring receptor variants and association analysis in schizophrenia Hum Genet 1996 97: 614-619 

  27. Neuropsychopharmacology K Ohara 17 274 1997 10.1016/S0893-133X(97)00052-3 Ohara K, Ino A, Ishigaki T, Tani K, Tsukamoto T, Nakamura Y . Analysis of the 5′-flanking promoter region of the 5-HT2A receptor gene in schizophrenia Neuropsychopharmacology 1997 17: 274-278 

  28. Mol Psychiatry G Spurlock 3 42 1998 10.1038/sj.mp.4000342 Spurlock G, Heils A, Holmans P, Williams J, D'Souza UM, Cardno A et al. A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter Mol Psychiatry 1998 3: 42-49 

  29. Hum Hered AH Tay 47 298 1997 10.1159/000154428 Tay AH, Lim LC, Lee WL, Wong KE, Wong LY, Tsoi WF . Association between allele 1 of T102C polymorphism, 5-hydroxytryptamine 2a receptor gene and schizophrenia in Chinese males in Singapore Hum Hered 1997 47: 298-300 

  30. Am J Med Genet Z Hawi 74 370 1997 10.1002/(SICI)1096-8628(19970725)74:4<370::AID-AJMG6>3.0.CO;2-T Hawi Z, Myakishev MV, Straub RE . No association or linkage between the 5-HT2a/T102C polymorphism and schizophrenia in Irish families Am J Med Genet 1997 74: 370-373 

  31. Hum Hered AP Kouzmenko 49 103 1999 10.1159/000022853 Kouzmenko AP, Scaffidi A, Pereira AM, Hayes WL, Copolov DL, Dean B . No correlation between A(-1438)G polymorphism in 5-HT2A receptor gene promoter and the density of frontal cortical 5-HT2A receptors in schizophrenia Hum Hered 1999 49: 103-105 

  32. Psychiatry Res K Ohara 85 221 1999 10.1016/S0165-1781(99)00002-5 Ohara K, Nagai M, Tani K, Tsukamoto T . Schizophrenia and the serotonin-2A receptor promoter polymorphism Psychiatry Res 1999 85: 221-224 

  33. Hum Hered T Shinkai 48 212 1998 10.1159/000022803 Shinkai T, Ohmori O, Kojima H, Terao T, Suzuki T, Abe K . Negative association between T102C polymorphism of the 5-HT2a receptor gene and schizophrenia in Japan Hum Hered 1998 48: 212-215 

  34. Schizophr Res MJ Arranz 32 93 1998 10.1016/S0920-9964(98)00032-2 Arranz MJ, Munro J, Sham P . Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response Schizophr Res 1998 32: 93-99 

  35. Neuropsychopharmacology M Masellis 19 123 1998 10.1016/S0893-133X(98)00007-4 Masellis M, Basile V, Meltzer HY . Serotonin subtype 2 receptor genes and clinical response to clozapine in schizophrenia patients Neuropsychopharmacology 1998 19: 123-132 

  36. Am J Psychiatry AK Malhotra 153 1092 1996 10.1176/ajp.153.8.1092 Malhotra AK, Goldman D, Ozaki N, Breier A, Buchanan R, Pickar D . Lack of association between polymorphisms in the 5-HT2A receptor gene and the antipsychotic response to clozapine Am J Psychiatry 1996 153: 1092-1094 

  37. Am J Psychiatry G Turecki 156 1456 1999 10.1176/ajp.156.9.1456 Turecki G, Briere R, Dewar K . Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide Am J Psychiatry 1999 156: 1456-1458 

  38. Neurosci Lett B Nacmias 277 134 1999 10.1016/S0304-3940(99)00859-9 Nacmias B, Ricca V, Tedde A, Mezzani B, Rotella CM, Sorbi S . 5-HT2A receptor gene polymorphism in anorexia nervosa and bulimia nervosa Neurosci Lett 1999 277: 134-136 

  39. J Clin Psychopharmacol G Muscettola 19 203 1999 10.1097/00004714-199906000-00002 Muscettola G, Giuseppe B, Pampallona S, Casiello M, Bolini P . Extrapyramidal syndromes in neuroleptic-treated patients: prevalence risk factors and association with tardive dyskinesia J Clin Psychopharmacol 1999 19: 203-208 

  40. Psychopharmacology (Berl) JS Paulsen 123 307 1996 10.1007/BF02246639 Paulsen JS, Caligiuri MP, Palmer B, McAdams LA, Jeste DV . Risk factors for orofacial and limbtruncal tardive dyskinesia in older patients: a prospective longitudinal study Psychopharmacology (Berl) 1996 123: 307-314 

  41. J Neurol Neurosurg Psychiatry O Gureje 51 1525 1988 10.1136/jnnp.51.12.1525 Gureje O . Topographic subtypes of TD in schizophrenic patients aged less than 60 years: relationship to demographic clinical treatment and neuropsychological variables J Neurol Neurosurg Psychiatry 1988 51: 1525-1530 

  42. Br J Psychiatry WM Glazer 152 253 1988 10.1192/bjp.152.2.253 Glazer WM, Morgenstern H, Niedzweicki D, Hughes J . Heterogeneity of tardive dyskinesia. A multivariate analysis Br J Psychiatry 1988 152: 253-259 

  43. Arch Gen Psychiatry NR Schooler 39 486 1982 Schooler NR, Kane JM . Research diagnoses for tardive dyskinesia Arch Gen Psychiatry 1982 39: 486-487 

  44. W Guy 1976 ECDEU Assessment Manual for Psychopharmacology, revised edition Guy W . ECDEU Assessment Manual for Psychopharmacology, revised edition Department of Health, Education and Welfare, Washington DC 1976 

  45. SR Kay 1987 Positive and Negative Syndrome Scale (PANSS) Rating Manual Kay SR, Opler LA . Positive and Negative Syndrome Scale (PANSS) Rating Manual Social and Behavioral Sciences Documents San Rafael, CA 1987 

  46. Acta Psychiatr Scand GM Simpson 212 11 1970 10.1111/j.1600-0447.1970.tb02066.x Simpson GM, Angus JWS . A rating scale for extrapyramidal side effects Acta Psychiatr Scand 1970 212: (Suppl) 11-19 

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