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Activated p56lck Directs Maturation of Both CD4 and CD8 Single-Positive Thymocytes 원문보기

The journal of immunology : official journal of the American Association of Immunologists, v.166 no.4, 2001년, pp.2209 - 2217  

Sohn, Sue J. (*Department of Immunology, University of Washington, Seattle, WA 98195) ,  Forbush, Katherine A. (and) ,  Pan, Xiao Cun (*Department of Immunology, University of Washington, Seattle, WA 98195) ,  Perlmutter, Roger M. (and)

Abstract AI-Helper 아이콘AI-Helper

Abstractp56lck is a protein tyrosine kinase expressed throughout T cell development. It associates noncovalently with the cytoplasmic domains of the CD4 and CD8 coreceptor molecules and has been implicated in TCR signaling in mature T cells. Its role in early thymocyte differentiation has been demon...

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