$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

A Role for IFN-αβ in Virus Infection-Induced Sensitization to Endotoxin 원문보기

The journal of immunology : official journal of the American Association of Immunologists, v.166 no.4, 2001년, pp.2658 - 2664  

Doughty, Lesley A. (*Pediatrics and) ,  Nguyen, Khuong B. (†Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University, Providence, RI 02912) ,  Durbin, Joan E. (and) ,  Biron, Christine A. (‡Division of Pediatric Pathology, Department of Pediatrics, College of Medicine and Public Health, Ohio State University, Columbus, OH 43210)

Abstract AI-Helper 아이콘AI-Helper

AbstractUnderlying viral infections can heighten sensitivity and worsen cytokine-mediated disease following secondary inflammatory challenges. Mechanisms for this are poorly understood. The impact of the innate response to lymphocytic choriomeningitis virus (LCMV) infection on sensitivity to endotox...

참고문헌 (47)

  1. 10.7326/0003-4819-119-8-199310150-00001 Casey, L. C., R. A. Balk, R. C. Bone. 1993. Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann. Intern. Med. 119: 771 

  2. 10.4049/jimmunol.157.11.5049 Zhang, W. J., S. Sarawar, P. Nguyen, K. Daly, J. E. Rehg, P. C. Doherty, D. L. Woodland, M. A. Blackman. 1996. Lethal synergism between influenza infection and staphylococcal enterotoxin B in mice. J. Immunol. 157: 5049 

  3. 10.1084/jem.181.3.901 Orange, J. O., T. P. Salazar-Mather, S. M. Opal, R. L. Spencer, A. H. Miller, B. S. McEwen, C. A. Biron. 1995. Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids. J. Exp. Med. 181: 901 

  4. 10.4049/jimmunol.162.9.5238 Nguyen, K. B., C. A. Biron. 1999. Synergism for cytokine-mediated disease during concurrent endotoxin and viral challenges: roles for NK and T cell IFN-γ production. J. Immunol. 162: 5238 

  5. Ray, G. C.. 1994. Influenza, respiratory syncytial, adenovirus, and other respiratory viruses. K. J. Ryan, ed. Sherris Medical Microbiology: An Introduction to Infectious Diseases 3rd Ed.456 Appleton and Lange Paramount Publishing Business and Professional Group, East Norwalk, CT. 

  6. 10.1001/jama.1987.03390080043027 MacDonald, K. L., M. T. Osterholm, C. W. Hedberg, C. G. Schrock, J.M. Peterson Jentzen, S. A. Leonard, P. M. Schlievert. 1987. Toxic shock syndrome: a newly recognized complication of influenza and influenza-like illness. J. Am. Med. Assoc. 257: 1053 

  7. 10.1093/infdis/118.5.449 Degre, M., L. A. Glasgow. 1968. Synergistic effect in viral-bacterial infection. I. Combined infection of the respiratory tract in mice with parainfluenza virus and Haemophilus influenzae. J. Infect. Dis. 118: 449 

  8. 10.1136/bmj.313.7065.1145a Barnes, A. J., A. S. Johnson, M. P. Shelly, C. I. Orton. 1996. Bacterial superinfection in chickenpox but it can occur at any age. Br. Med. J. 313: 1145 

  9. 10.1542/peds.103.4.783 Zerr, D. M., E. R. Alexander, J. S. Duchin, L. A. Koutsky, C. E. Rubens. 1999. A case-control study of necrotizing fasciitis during primary varicella. Pediatrics 103: 783 

  10. 10.1128/iai.41.2.618-623.1983 Jones, W. T., J. H. Menna, D. E. Wennerstrom. 1983. Lethal synergism induced in mice by influenza type A and type Ia group B streptococci. Infect. Immun. 41: 618 

  11. 10.1093/infdis/170.5.1189 Sarawar, S. R., M. A. Blackman, P. C. Doherty. 1994. Superantigen shock in mice with inapparent viral infection. J. Infect. Dis. 170: 1189 

  12. 10.1086/514017 Nansen, A., J. P. Christensen, O. Marker, A. R. Thomsen. 1997. Sensitization to lipopolysaccharide in mice with asymptomatic viral infection: the role of T cell dependent production of interferon γ. J. Infect. Dis. 176: 151 

  13. 10.4049/jimmunol.155.9.4497 Pullen, L. C., S. H. Park, S. D. Miller, M. C. Dal Canto, B. S. Kim. 1995. Treatment with bacterial LPS renders genetically resistant C57BL/6 mice susceptible to Theiler’s virus-induced demyelinating disease. J. Immunol. 155: 4497 

  14. 10.1111/j.1348-0421.1986.tb03003.x Leung, W. C., K. Hashimoto. 1986. Modification of susceptibility to K. pneumoniae during murine cytomegalovirus infection. Microbiol. Immunol. 30: 761 

  15. Murray, P. R., K. S. Rosenthal, G. S. Kobayashi, M. A. Pfaller. 1998. Orthomyxoviruses. M. Brown, ed. Medical Microbiology 3rd Ed.477 Mosby-Year Book, St. Louis, MO. 

  16. 10.1084/jem.180.3.907 Ozmen, L., M. Pericin, J. Hakimi, R. A. Chizzonite, M. Wysocka, G. Trinchieri, M. Gately, G. Garotta. 1994. Interleukin 12, interferon-γ, and tumor necrosis factor-α are the key cytokines of the generalized Schwartzman reaction. J. Exp. Med. 180: 907 

  17. 10.1128/iai.62.10.4244-4249.1994 Heinzel, F. P., R. M. Rerko, P. Ling, J. Hakimia, D. S. Schoenhaut. 1994. Interleukin 12 is produced in vivo during endotoxemia and stimulates synthesis of γ interferon. Infect. Immun. 62: 4244 

  18. 10.1002/eji.1830250307 Wysocka, M., M. Kubin, L. Q. Vieira, L. Ozmen, G. Garotta, P. Scott, G. Trinchieri. 1995. Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice. Eur. J. Immunol. 25: 672 

  19. 10.1084/jem.171.6.1853 Heremans, H., J. Van Damme, C. Dillen, R. Dijkmans, A. Billiau. 1990. Interferon-γ, a mediator of lethal lipopolysaccharide-induced Shwartzman-like shock reactions in mice. J. Exp. Med. 171: 1853 

  20. 10.4049/jimmunol.145.9.2920 Heinzel, F. P.. 1990. The role of IFN-γ in the pathology of experimental endotoxemia. J. Immunol. 145: 2920 

  21. 10.4049/jimmunol.135.6.3972 Beutler, B. A., I. W. Milsark, A. Cerami. 1985. Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo. J. Immunol. 135: 3972 

  22. 10.1126/science.3895437 Beutler, B., I. W. Milsark, A. C. Cerami. 1985. Passive immunization against cachectin-tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229: 869 

  23. 10.1016/0092-8674(93)90134-C Pfeffer, K., T. Matsuyama, T. M. Kundig, A. Wakeham, K. Kishihara, A. Shchinian, K. Wiegmann, P. S. Ohashi, M. Kronke, T. W. Mak. 1993. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73: 457 

  24. 10.1084/jem.165.3.657 Lehmann, V., M. A. Freudenberg, C. Galanos. 1987. Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice. J. Exp. Med. 165: 657 

  25. 10.1073/pnas.84.12.4273 Kettelhut, I. C., W. Fiers, A. L. Goldberg. 1987. The toxic effects of tumor necrosis factor in vivo and their prevention by cyclo-oxygenase inhibitors. Proc. Natl. Acad. Sci. USA 84: 4273 

  26. 10.1172/JCI113733 Starnes, H. F., Jr, R. S. Warren, M. Jeevanandam, J. L. Gabrilove, W. Larchian, H. F. Oettgen, M. F. Brennan. 1988. Tumor necrosis factor and the acute metabolic response to tissue injury in man. J. Clin. Invest. 82: 1321 

  27. 10.1038/318665a0 Aggarwal, B. B., T. E. Eessalu, P. E. Hass. 1985. Characterization of receptors for human tumor necrosis factor and their regulation by γ-interferon. Nature 318: 665 

  28. 10.4049/jimmunol.136.7.2441 Tsujimoto, M., Y. K. Yip, J. Vilcek. 1986. Interferon-γ enhances expression of cellular receptors for tumor necrosis factor. J. Immunol. 136: 2441 

  29. 10.4049/jimmunol.149.5.1666 Doherty, G. M., J. R. Lange, H. N. Langstein, R. Alexander, C. M. Buresh, J. A. Norton. 1992. Evidence for IFN-γ as a mediator of the lethality of endotoxin and tumor necrosis factor-α. J. Immunol. 149: 1666 

  30. 10.4049/jimmunol.142.7.2325 Hamilton, T. A., N. Bredon, Y. Ohmori, C. S. Tannenbaum. 1989. IFN-γ and IFN-β independently stimulate the expression of lipopolysaccharide-inducible genes in murine peritoneal macrophages. J. Immunol. 142: 2325 

  31. 10.4049/jimmunol.141.5.1536 Moon, D. K., C. L. Geczy. 1988. Recombinant IFN-γ synergizes with lipopolysaccharide induce macrophage membrane procoagulants. J. Immunol. 141: 1536 

  32. Biron, C. A., and G. C. Sen. 2001. Interferons and other cytokines. In Fields Virology, 4th Ed. D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus, eds. Lippincott, Williams, & Wilkins, In press. 

  33. 10.1006/smim.1998.0138 Biron, C. A.. 1998. Role of early cytokines, including alpha and beta interferons (IFN-α/β), in innate and adaptive immune responses to viral infections. Semin. Immunol. 10: 383 

  34. 10.1073/pnas.94.2.634 Cousens, L. P., J. S. Orange, H. C. Su, C. A. Biron. 1997. Interferon-α/β inhibition of interleukin 12 and interferon-γ production in vitro and endogenously during viral infection. Proc. Natl. Acad. Sci. USA 94: 634 

  35. 10.1038/76940 Nguyen, K. B., L. C. Cousens, L. A. Doughty, G. C. Pien, J. E. Durbin, C. A. Biron. 2000. Interferon-α/β-mediated inhibition and promotion of interferon-γ: STAT1 resolves a paradox. Nat. Immunol. 1: 70 

  36. Pfeffer, L. M., C. A. Dinarello, R. B. Herberman, B. R. G. Williams, E. C. Borden, R. Bordens, M. R. Walter, T. L. Nagabhushan, P. P. Trotta, S. Pestka. 1998. Biological properties of recombinant α-interferons: 40th anniversary of the discovery of interferons. Cancer Res. 58: 2489 

  37. 10.1200/JCO.2000.18.12.2444 Kirkwood, J. M., J. G. Ibrahim, V. K. Sondak, J. Richards, L. E. Flaherty, M. S. Ernstrobb, T. J. Smith, U. Rao, M. Steele, R. H. Blum. 2000. High- and low-dose interferon α-2b in high-risk melanoma: analysis of intergroup trial E1690/S9111/C9190. J Clin. Oncol. 18: 2444 

  38. Giosue, S., M. Casarini, F. Ameglio, P. Zangrilli, M. Palla, A. M. Altieri. 2000. Aerosolized interferon-α treatment in patients with multi-resistant pulmonary tuberculosis. Eur. Cytokine Network 11: 99 

  39. Ganapati, R., V. V. Pai, U. Banerji, J. Thomas, B. Saha. 1997. A multicenter study of recombinant interferon-α 2b in the treatment of multibacillary leprosy. Int. J. Lepr. Other Mycobact. Dis. 65: 495 

  40. 10.1073/pnas.91.20.9402 Wang, B., C. A. Biron, J. She, K. Higgins, M. J. Sunshine, E. Lacy, N. Lonberg, C. Terhorst. 1994. A block in both early T lymphocyte and natural killer cell development in transgenic mice with high copy numbers of the human CD3ε gene. Proc. Natl. Acad. Sci. USA 9: 9402 

  41. 10.1016/0092-8674(92)90030-G Mombaerts, P., J. Iacomini, R. S. Johnson, K. Herrup, S. Tonegawa, V. E. Papaioannou. 1992. RAG-1 deficient mice have no mature B and T lymphocytes. Cell 68: 869 

  42. 10.4049/jimmunol.160.10.5007 Su, H. C., L. P. Cousens, L. D. Fast, M. K. Slifka, R. D. Bungiro, R. Ahmed, C. A. Biron. 1998. CD4+ and CD8+ T cell interactions in IFN-γ and IL-4 responses to viral infections: requirements for IL-2. J. Immunol. 160: 5007 

  43. 10.1084/jem.182.4.1045 Orange, J. S., B. Wang, C. Terhorst, C. A. Biron. 1995. Requirement for natural killer cell-produced interferon γ in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration. J. Exp. Med. 182: 1045 

  44. 10.1038/382171a0 Thierfelder, W. E., J. M. van Deursen, K. Yamamoto, R. A. Tripp, T. Sarawar, R. T. Carson, M. Y. Sangster, D. A. Vignali, P. C. Doherty, G. C. Grosveld, J. N. Ihle. 1996. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 382: 171 

  45. 10.4049/jimmunol.162.12.7417 Kantakamalakul, W., A. D. Politis, S. Marecki, T. Sullivan, K. Ozato, M. J. Fenton, S. N. Vogel. 1999. Regulation of IFN consensus sequence binding protein expression in murine macrophages. J. Immunol. 162: 7417 

  46. 10.1128/IAI.67.1.206-212.1999 Held, T. K., X. Weihua, L. Yuan, D. V. Kalvakolanu, A. S. Cross. 1999. γ interferon augments macrophage activation by lipopolysaccharide by two distinct mechanisms, at the signal transduction level via an autocrine mechanism involving tumor necrosis factor α and interleukin 1. Infect. Immun. 67: 206 

  47. 10.1002/eji.1830221211 Tzung, S. P., T. C. Mahl, P. Lance, V. Andersen, S. A. Cohen. 1993. Interferon-α prevents endotoxin-induced mortality in mice. Eur. J. Immunol. 22: 3097 

관련 콘텐츠

오픈액세스(OA) 유형

BRONZE

출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로