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[해외논문] Immunogenetic analysis reveals that epitope shifting occurs during B-cell affinity maturation in primary biliary cirrhosis

Journal of molecular biology, v.306 no.1, 2001년, pp.37 - 46  

Potter, K.N. ,  Thomson, R.K. ,  Hamblin, A. ,  Richards, S.D. ,  Lindsay, J. ,  Stevenson, F.K.

Abstract AI-Helper 아이콘AI-Helper

Primary biliary cirrhosis (PBC) is a liver disease characterized by serum autoantibodies against the pyruvate dehydrogenase complex (PDC) located in the inner mitochondrial membrane. The predominant target in PDC has previously been localized to the inner lipoyl domain (ILD) of the E2 subunit. The e...

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참고문헌 (34)

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