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NTIS 바로가기Nature, v.410 no.6825 = no.6825, 2001년, pp.227 - 230
Tissenbaum, Heidi A. , Guarente, Leonard
In Caenorhabditis elegans, mutations that reduce the activity of an insulin-like receptor (daf-2) or a phosphatidylinositol-3-OH kinase (age-1) favour entry into the dauer state during larval development and extend lifespan in adults. Downregulation of this pathway activates a forkhead transcription...
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