$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[해외논문] Efficacy of 2-Amino-7-(1,3-Dihydroxy-2-Propoxymethyl)Purine for Treatment of Vaccinia Virus (Orthopoxvirus) Infections in Mice 원문보기

Antimicrobial agents and chemotherapy, v.45 no.1, 2001년, pp.84 - 87  

Neyts, Johan (<) ,  De Clercq, Erik (!--label omitted: 1-->)

Abstract AI-Helper 아이콘AI-Helper

ABSTRACTWe have previously shown that the N-7 substituted acyclic nucleoside analog 2-amino-7-[1,3-dihydroxy-2-propoxy)methyl]purine (compound S2242) is, both in vitro and in animal models, a potent inhibitor of the replication of several herpesviruses (Neyts et al., Antimicrob. Agents Chemother. 39...

참고문헌 (21)

  1. Morb. Mortal. Wkly. Rep. Anonymous 1168 46 1997 Human monkeypox-Kasai Oriental, Democratic Republic of Congo, February 1996-October 1997. Anonymous Human monkeypox-Kasai Oriental, Democratic Republic of Congo, February 1996-October 1997. Morb. Mortal. Wkly. Rep. 46 1997 1168 1171 

  2. Bauer, D.J., Vincent, L., Kempe, C.H., Downie, A.W.. PROPHYLACTIC TREATMENT OF SMALLPOX CONTACTS WITH N-METHYLISATIN β-THIOSEMICARBAZONE (COMPOUND 33T57, MARBORAN). The Lancet, vol.282, no.7306, 494-496.

  3. International encyclopedia of pharmacology and therapeutics Bauer D. J. 35 1972 Thiosemicarbazones Bauer D. J. Thiosemicarbazones International encyclopedia of pharmacology and therapeutics I. Chemotherapy of viral diseases 1972 35 113 Pergamon Press Ltd. Oxford, United Kingdom 

  4. Bray, M, Martinez, M, Smee, D F, Kefauver, D, Thompson, E, Huggins, J W. Cidofovir protects mice against lethal aerosol or intranasal cowpox virus challenge.. The Journal of infectious diseases : official publication of the Infectious Diseases Society of America, vol.181, no.1, 10-19.

  5. Breman, Joel G., Henderson, D.A.. Poxvirus Dilemmas - Monkeypox, Smallpox, and Biologic Terrorism. The New England journal of medicine, vol.339, no.8, 556-559.

  6. Davies, EG, Thrasher, A, Lacey, K, Harper, J. Topical cidofovir for severe molluscum contagiosum. The Lancet, vol.353, no.9169, 2042-2042.

  7. Clercq, Erik De, Holý, Antonin, Rosenberg, Ivan, Sakuma, Takashi, Balzarini, Jan, Maudgal, Parbhat C.. A novel selective broad-spectrum anti-DNA virus agent. Nature, vol.323, no.6087, 464-467.

  8. De Clercq, E, Holý, A, Rosenberg, I. Efficacy of phosphonylmethoxyalkyl derivatives of adenine in experimental herpes simplex virus and vaccinia virus infections in vivo. Antimicrobial agents and chemotherapy, vol.33, no.2, 185-191.

  9. De Clercq E. Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections. Clin. Microbiol. Rev. in press. 

  10. Geerinck K. G. Lukito R. Snoeck R. De Vos E. De Clercq Y. Vanrenterghem H. Degreef and B. Maes. A case of human orf in an immunocompromised patient successfully treated with cidofovir cream. J. Med. Virol. in press. 

  11. Lancet Guillaume J. C. 1034 337 1991 10.1016/0140-6736(91)92689-Y Vaccinia from recombinant virus expressing HIV genes. Guillaume J. C. Saiag P. Wechsler J. Lescs M. C. Roujeau J. C. Vaccinia from recombinant virus expressing HIV genes. Lancet 337 1991 1034 1035 

  12. Heymann, D L, Szczeniowski, M, Esteves, K. Re-emergence of monkeypox in Africa: a review of the past six years.. British medical bulletin, vol.54, no.3, 693-702.

  13. N. Engl. J. Med. Hooper C. 2027 339 1998 10.1056/NEJM199812313392717 Poxvirus dilemmas. Hooper C. Poxvirus dilemmas. N. Engl. J. Med. 339 1998 2027 2028 

  14. Angew. Chem. Int. Ed. Engl. Jahne G. 562 33 1994 10.1002/anie.199405621 Regioselective synthesis and antiviral activity of purine nucleoside analogues with acyclic substituents at N7. Jahne G. Kroha H. Muller A. Helsberg M. Winkler I. Gross G. Scholl T. Regioselective synthesis and antiviral activity of purine nucleoside analogues with acyclic substituents at N7. Angew. Chem. Int. Ed. Engl. 33 1994 562 563 

  15. 10.1001/archderm.1997.03890440061010 

  16. Lancet Mukinda V. B. 1449 349 1997 10.1016/S0140-6736(05)63725-7 Re-emergence of human monkeypox in Zaire in 1996. Monkeypox Epidemiologic Working Group. Mukinda V. B. Mwema G. Kilundu M. Heymann D. L. Khan A. S. Esposito J. J. Re-emergence of human monkeypox in Zaire in 1996. Monkeypox Epidemiologic Working Group. Lancet 349 1997 1449 1455 

  17. J. Med. Virol. Neyts J. 242 41 1993 10.1002/jmv.1890410312 Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine for the treatment of lethal vaccinia virus infections in severe combined immune deficiency (SCID) mice. Neyts J. De Clercq E. Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine for the treatment of lethal vaccinia virus infections in severe combined immune deficiency (SCID) mice. J. Med. Virol. 41 1993 242 246 

  18. Neyts, J, Andrei, G, Snoeck, R, Jähne, G, Winkler, I, Helsberg, M, Balzarini, J, De Clercq, E. The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication. Antimicrobial agents and chemotherapy, vol.38, no.12, 2710-2716.

  19. Neyts, J, Jähne, G, Andrei, G, Snoeck, R, Winkler, I, De Clercq, E. In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine. Antimicrobial agents and chemotherapy, vol.39, no.1, 56-60.

  20. Neyts, Johan, Balzarini, Jan, Andrei, Graciela, Chaoyong, Zhu, Snoeck, Robert, Zimmermann, Albert, Mertens, Thomas, Karlsson, Anna, De Clercq, Erik. Intracellular Metabolism of the N7-Substituted Acyclic Nucleoside Analog 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, a Potent Inhibitor of Herpesvirus Replication. Molecular pharmacology, vol.53, no.1, 157-165.

  21. N. Engl. J. Med. Redfield R. R. 673 316 1987 10.1056/NEJM198703123161106 Disseminated vaccinia in a military recruit with human immunodeficiency virus (HIV) disease. Redfield R. R. Wright D. C. James W. D. Jones T. S. Brown C. Burke D. S. Disseminated vaccinia in a military recruit with human immunodeficiency virus (HIV) disease. N. Engl. J. Med. 316 1987 673 676 

관련 콘텐츠

오픈액세스(OA) 유형

BRONZE

출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로