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[해외논문] Haploinsufficiency of Cyfip2 Causes Lithium‐Responsive Prefrontal Dysfunction

Annals of neurology, v.88 no.3, 2020년, pp.526 - 543  

Lee, Seung‐Hyun (Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry) ,  Zhang, Yinhua (Department of Neuroscience, College of Medicine, Korea University) ,  Park, Jina (Center for Neuroscience, Korea Institute of Science and Technology, Seoul) ,  Kim, Bowon (Center for Neuroscience, Korea Institute of Science and Technology, Seoul) ,  Kim, Yangsik (Center for Synaptic Brain Dysfunctions, Institute for Basic Science, Daejeon) ,  Lee, Sang Hoon (Neural Circuits Research Group, Korea Brain Research Institute, Daegu) ,  Kim, Gyu Hyun (Neural Circuits Research Group, Korea Brain Research Institute, Daegu) ,  Huh, Yang Hoon (Center for Electron Microscopy Research, Korea Basic Science Institute, Chungcheongbuk‐) ,  Lee, Bokyoung (do) ,  Kim, Yoonhee (Department of Neuroscience, College of Medicine, Kore) ,  Lee, Yeunkum ,  Kim, Jin Yong ,  Kang, Hyojin ,  Choi, Su‐Yeon ,  Jang, Seil ,  Li, Yan ,  Kim, Shinhyun ,  Jin, Chunmei ,  Pang, Kaifang ,  Kim, Eunjeong ,  Lee, Yoontae ,  Kim, Hyun ,  Kim, Eunjoon ,  Choi, Jee Hyun ,  Kim, Jeongjin ,  Lee, Kea Joo ,  Choi, Se‐Young ,  Han, Kihoon

Abstract AI-Helper 아이콘AI-Helper

ObjectiveGenetic variants of the cytoplasmic FMR1‐interacting protein 2 (CYFIP2) encoding an actin‐regulatory protein are associated with brain disorders, including intellectual disability and epilepsy. However, specific in vivo neuronal defects and potential treatments for CYFIP2‐...

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