최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Developmental biology, v.230 no.2, 2001년, pp.110 - 124
Fortuno, E.S. , LeSueur, J.A. , Graff, J.M.
Smad proteins transduce transforming growth factor-β signals from the cell surface to the nucleus, regulating a variety of physiologic processes. In the nucleus, Smads control gene expression by binding to both DNA and transcription factors. Individual Smads regulate distinct subsets of target ...
Genes & Dev. Baker 10 1880 1996 10.1101/gad.10.15.1880 A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway
Nature Chen 383 691 1996 10.1038/383691a0 A transcriptional partner for MAD proteins in TGFβ signalling
Nature Chen 389 85 1997 10.1038/38008 Smad4 and FAST-1 in the assembly of activin-responsive factor
Proc. Natl. Acad. Sci. USA Chen 94 12938 1997 10.1073/pnas.94.24.12938 Smad8 mediates the signaling of the receptor serine kinase
Genes & Dev. Chen 12 2144 1998 10.1101/gad.12.14.2144 Determinants of specificity in TGF-β signal transduction
Proc. Natl. Acad. Sci. USA Chien 88 9578 1991 10.1073/pnas.88.21.9578 The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest
EMBO J. Dennler 17 3091 1998 10.1093/emboj/17.11.3091 Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
Cell Eppert 86 543 1996 10.1016/S0092-8674(00)80128-2 MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
Genes & Dev. Germain 14 435 2000 10.1101/gad.14.4.435 Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif
Cell Graff 85 479 1996 10.1016/S0092-8674(00)81249-0 Xenopus Mad proteins transduce distinct subsets of signals for the TGFβ superfamily
Cell Graff 79 169 1994 10.1016/0092-8674(94)90409-X Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo
Science Hahn 271 350 1996 10.1126/science.271.5247.350 DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
Genes & Dev. Hata 12 186 1998 10.1101/gad.12.2.186 Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
Nature Hata 388 82 1997 10.1038/40424 Mutations increasing autoinhibition inactivate the tumour suppressors Smad2 and Smad4
Mol. Med. Today Hata 4 257 1998 10.1016/S1357-4310(98)01247-7 TGF-β signaling and cancer: Structural and functional consequences of mutations in Smads
Cell Hayashi 89 1165 1997 10.1016/S0092-8674(00)80303-7 The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
Nature Heldin 390 465 1997 10.1038/37284 TGF-β signalling from cell membrane to nucleus through SMAD proteins
Development Hemmati-Brivanlou 110 325 1990 10.1242/dev.110.2.325 Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization
Cell Hemmati-Brivanlou 77 273 1994 10.1016/0092-8674(94)90319-0 Inhibition of activin receptor signaling promotes neuralization in Xenopus
Dev. Genet. Hemmati-Brivanlou 17 78 1995 10.1002/dvg.1020170109 Ventral mesoderal patterning in Xenopus embryos: Expression patterns and activities of BMP2 and BMP4
Cell Hoodless 85 489 1996 10.1016/S0092-8674(00)81250-7 MADR1, a MAD-related protein that functions in BMP2 signaling pathways
Gene Horton 77 61 1989 10.1016/0378-1119(89)90359-4 Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension
Dev. Biol. Howell 214 354 1999 10.1006/dbio.1999.9430 Xenopus Smad4β is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes
Genes & Dev. Hua 12 3081 1998 10.1101/gad.12.19.3084 Synergistic cooperation of the TFE3 and Smad proteins in the TGF-β-induced transcription of the plasminogen activator inhibitor-1 gene
Nature Imamura 389 622 1997 10.1038/39355 Smad6 inhibits signalling by the TGFβ superfamily
Nature Kim 388 304 1997 10.1038/40906 Drosophila Mad binds to DNA and directly mediates activation of vestigal by Decapentaplegic
Development Kintner 99 311 1987 10.1242/dev.99.3.311 Expression of Xenopus N-CAM RNA in ectoderm is an early response to neural induction
Genes & Dev. Kretzschmar 11 984 1997 10.1101/gad.11.8.984 The TGFβ family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase
Dev. Biol. Krieg 133 93 1989 10.1016/0012-1606(89)90300-X The mRNA encoding elongation factor 1α (EF-1α) is a major transcript at the mid blastula transition in Xenopus
Mol. Cell Labbe 2 109 1998 10.1016/S1097-2765(00)80119-7 Smad2 and Smad3 positively and negatively regulate TGFβ-dependent transcription through the forkhead DNA-binding protein FAST-2
Nature Lagna 383 832 1996 10.1038/383832a0 Partnership between DPC4 and SMAD proteins in TGFβ signalling pathways
Dev. Dyn. Lagna 21 269 1999 10.1002/(SICI)1097-0177(199903)214:3<269::AID-AJA10>3.0.CO;2-# A molecular basis for Smad specificity
Development LeSueur 126 137 1999 10.1242/dev.126.1.137 Spemann organizer activity of Smad10
Annu. Rev. Immunol. Letterio 16 137 1998 10.1146/annurev.immunol.16.1.137 Regulation of immune responses by TGF-β
Proc. Natl. Acad. Sci. USA Liberati 96 4844 1999 10.1073/pnas.96.9.4844 Smads bind directly to the Jun family of AP-1 transcription factors
Mol. Cell. Biol. Liu 19 424 1999 10.1128/MCB.19.1.424 FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor β signals
Nature Liu 381 620 1996 10.1038/381620a0 A human Mad protein acting as a BMP-regulated transcriptional activator
Genes & Dev. Liu 11 3157 1997 10.1101/gad.11.23.3157 Dual roles of Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes
Cell Macias-Silva 87 1215 1996 10.1016/S0092-8674(00)81817-6 MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling
J. Biol. Chem. Macias-Silva 273 25628 1998 10.1074/jbc.273.40.25628 Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2
Annu. Rev. Biochem. Massague 67 753 1998 10.1146/annurev.biochem.67.1.753 TGF-β signal transduction
Genes & Dev. Massague 14 627 2000 10.1101/gad.14.6.627 Controlling TGF-β signaling
J. Biol. Chem. Masuyama 274 12163 1999 10.1074/jbc.274.17.12163 Identification of two Smad4 proteins in Xenopus
Mech. Dev. Meersseman 61 127 1997 10.1016/S0925-4773(96)00629-6 The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in Xenopus embryo and transcriptional activation
Nature Mohun 311 716 1984 10.1038/311716a0 Cell type specific activation of actin genes in the early amphibian embryo
Proc. Natl. Acad. Sci. USA Moustakas 95 6733 1998 10.1073/pnas.95.12.6733 Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between SP1 and Smad family members
Nature Nakao 389 631 1997 10.1038/39369 Identification of Smad7, a TGFβ-inducible antagonist of TGFβ signalling
EMBO J. Nakao 16 5353 1997 10.1093/emboj/16.17.5353 TGF-β receptor-mediated signaling through Smad2, Smad3 and Smad4
J. Biol. Chem. Nakao 272 2896 1997 10.1074/jbc.272.5.2896 Identification of Smad2, a human Mad-related protein in the TGFβ signaling pathway
Nieuwkoop 1967 Normal Table of Xenopus laevis (Daudin)
Cancer Metastasis Rev. Padgett 18 247 1999 10.1023/A:1006325408261 TGF-β signaling pathways and human diseases
Trends Genet. Patterson 16 27 1999 10.1016/S0168-9525(99)01916-2 TGFβ-related pathways: roles in Caenorhabditis elegans development
Genes & Dev. Pawson 14 1027 2000 10.1101/gad.14.9.1027 Protein-protein interactions define specificity in signal transduction
FASEB J. Piek 13 2105 1999 10.1096/fasebj.13.15.2105 Specificity, diversity and regulation in TGF-β superfamily signaling
Nature Ptashne 335 683 1988 10.1038/335683a0 How eukaryotic transcriptional activators work
Science Rosa 239 783 1988 10.1126/science.3422517 Mesoderm induction in amphibians: The role of TGF-β2-like factors
Cell Shi 94 585 1998 10.1016/S0092-8674(00)81600-1 Crystal structure of a Smad MH1 domain bound to DNA: Insights on DNA binding in TGF-β signaling
Dev. Biol. Suzuki 184 402 1997 10.1006/dbio.1997.8548 Smad5 induces ventral fates in Xenopus embryo
Mol. Biol. Cell Tall 10 1873 1999 10.1091/mbc.10.6.1873 The phosphotidylinositol 3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting
J. Cell. Physiol. Tamaki 177 355 1998 10.1002/(SICI)1097-4652(199811)177:2<355::AID-JCP17>3.0.CO;2-8 Intracellular signaling of osteogenic protein-1 through Smad5 activation
Trends Biochem. Sci. ten Dijke 25 64 2000 10.1016/S0968-0004(99)01519-4 Signaling inputs converge on nuclear effectors in TGF-β signaling
Nature Genetics Thomas 12 315 1996 10.1038/ng0396-315 A human chondrodysplasia due to a mutation in a TGF-β superfamily member
Development Thomsen 122 2359 1996 10.1242/dev.122.8.2359 Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor
Cell Thomsen 63 485 1990 10.1016/0092-8674(90)90445-K Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures
Cell Thomsen 74 433 1993 10.1016/0092-8674(93)80045-G Processed Vg1 protein is an axial mesoderm inducer in Xenopus
Development Watanabe 126 5621 1999 10.1242/dev.126.24.5621 FAST-1 is a key maternal effector in mesoderm inducers in early Xenopus embryo
Genes & Dev. Whitman 12 2445 1998 10.1101/gad.12.16.2445 Smads and early developmental signaling by the TGFβ superfamily
Curr. Biol. Wilson 4 676 1994 10.1016/S0960-9822(00)00152-4 Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication
Cell Wrana 100 189 2000 10.1016/S0092-8674(00)81556-1 Regulation of Smad activity
Mol. Cell. Biol. Wu 17 2521 1997 10.1128/MCB.17.5.2521 Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4
Mol. Cell. Biol. Yingling 17 7019 1997 10.1128/MCB.17.12.7019 Tumor suppressor Smad4 is a transforming growth factor β-inducible DNA binding protein
Mol. Cell Zawel 1 611 1998 10.1016/S1097-2765(00)80061-1 Human Smad3 and Smad4 are sequence-specific transcriptional activators
Nature Zhang 394 909 1998 10.1038/29814 Smad3 and Smad4 cooperate with the c-Jun/c-Fos to mediate TGF-β-induced transcription
Nature Zhang 383 168 1996 10.1038/383168a0 Receptor-associated Mad homologues synergize as effectors of the TGFβ response
Curr. Biol. Zhang 7 270 1997 10.1016/S0960-9822(06)00123-0 The tumor suppressor Smad4/DPC4 as a central mediator of Smad function
Mol. Cell Zhou 2 121 1998 10.1016/S1097-2765(00)80120-3 Characterization of human FAST-1, a TGF-β and activin signal transducer
해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문
※ AI-Helper는 부적절한 답변을 할 수 있습니다.