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[해외논문] Loss of Heterozygosity on Chromosome 11q22-23 in Melanoma Is Associated with Retention of the Insertion Polymorphism in the Matrix Metalloproteinase-1 Promoter 원문보기

The American journal of pathology, v.158 no.2, 2001년, pp.691 - 697  

Noll, Walter W. (Department of Pathology, Dartmouth Medical School, Hanover) ,  Belloni, Dorothy R. (and The Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire) ,  Rutter, Joni L. (Department of Pathology, Dartmouth Medical School, Hanover) ,  Storm, Craig A. (and The Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire) ,  Schned, Alan R. (Department of Biochemistry, Dartmouth Medical School, Hanover) ,  Titus-Ernstoff, Linda (and The Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire) ,  Ernstoff, Marc S. (Department of Pathology, Dartmouth Medical School, Hanover) ,  Brinckerhoff, Constance E. (and The Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire)

Abstract AI-Helper 아이콘AI-Helper

Matrix metalloproteinase-1 (MMP-1, collagenase-1), which degrades interstitial collagen, is expressed at high levels by some tumor cells and is thought to enhance their invasiveness and metastatic potential. We recently described a common single nucleotide insertion polymorphism (2G allele) at &minu...

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  11. Clin Exp Metastasis Benbow 17 213 1999 10.1023/A:1006639214618 Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid 

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