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American journal of epidemiology, v.153 no.5, 2001년, pp.453 - 464
Schwartz, Brian S. (Division of Occupational and Environmental Health, Department of Environmental Health Sciences, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD.) , Lee, Byung-Kook (Institute of Industrial Medicine, Soonchunhyang University, Chonan, South Korea.) , Lee, Gap-Soo (Institute of Industrial Medicine, Soonchunhyang University, Chonan, South Korea.) , Stewart, Walter F. (Division of Occupational and Environmental Health, Department of Environmental Health Sciences, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD.) , Lee, Sung-Soo (Institute of Industrial Medicine, Soonchunhyang University, Chonan, South Korea.) , Hwang, Kyu-Yoon (Institute of Industrial Medicine, Soonchunhyang University, Chonan, South Korea.) , Ahn, Kyu-Dong (Institute of Industrial Medicine, Soonchunhyang University, Chonan, South Korea.) , Kim, Yong-Bae (Institute of Industrial Medicine, Soonchunhyang University, Chonan, South Korea.) , Bolla, Karen I. (Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD.) , Simon, David (Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD.) , Parsons, Patrick J. (Le) , Todd, Andrew C.
The authors performed a cross-sectional study to evaluate associations between blood lead, tibia lead, and dimercaptosuccinic acid (DMSA)-chelatable lead and measures of neurobehavioral and peripheral nervous system function among 803 lead-exposed workers and 135 unexposed controls in South Korea. The workers and controls were enrolled in the study between October 1997 and August 1999. Central nervous system function was assessed with a modified version of the World Health Organization Neurobehavioral Core Test Battery. Peripheral nervous system function was assessed by measuring pinch and grip strength and peripheral vibration thresholds. After adjustment for covariates, the signs of the β coefficients for blood lead were negative for 16 of the 19 tests and blood lead was a significant predictor of worse performance on eight tests. On average, for the eight tests that were significantly associated with blood lead levels, an increase in blood lead of 5 µg/dl was equivalent to an increase of 1.05 years in age. In contrast, after adjustment for covariates, tibia lead level was not associated with neurobehavioral test scores. Associations with DMSA-chelatable lead were similar to those for blood lead. In these currently exposed workers, blood lead was a better predictor of neurobehavioral performance than was tibia or DMSA-chelatable lead, mainly in the domains of executive abilities, manual dexterity, and peripheral motor strength.
10.1136/oem.52.1.2 Balbus-Kornfeld JM, Stewart W, Bolla KI, et al. Cumulative exposure to inorganic lead and neurobehavioral test performance in adults: an epidemiologic review. Occup Environ Med1995;52:2–12.
10.1212/WNL.48.3.639 Bleecker ML, Lindgren KN, Ford DP. Differential contribution of current and cumulative indices of lead dose to neuropsychological performance by age. Neurology1997;48:639–45.
10.1016/S0048-9697(97)84051-X Österberg K, Börjesson J, Gerhardsson L, et al. A neurobehavioral study of long-term occupational inorganic lead exposure. Sci Total Environ1997;201:39–51.
10.1136/oem.55.3.202 Hänninen H, Aitio A, Kovala T, et al. Occupational exposure to lead and neuropsychological dysfunction. Occup Environ Med1998;55:202–9.
10.1016/S0892-0362(97)00075-5 Payton M, Riggs KM, Spiro A, et al. Relations of bone and blood lead to cognitive function: The VA Normative Aging Study. Neurotoxicol Teratol1998;20:19–27.
10.1136/oem.55.8.507 Stokes L, Letz R, Gerr F, et al. Neurotoxicity in young adults 20 years after childhood exposure to lead: the Bunker Hill experience. Occup Environ Med1998;55:507–16.
10.1212/WNL.52.8.1610 Stewart WF, Schwartz BS, Simon D, et al. Neurobehavioral function and tibial and chelatable lead levels in 543 former organolead workers. Neurology1999;52:1610–17.
Johnson BL, Baker EL, Batawi M, et al. Prevention of neurotoxic illness in working populations. New York, NY: John Wiley and Sons, Inc, 1987.
10.1177/001872088202400409 Wilkinson RT, Houghton D. Field test of arousal: a portable reaction timer with data storage. Hum Factors1982;24:487–93.
Cassito MG, Camerino D, Hanninen WK. International Collaboration to Evaluate the WHO Neurobehavioral Core Test Battery. In: Johnson BL, ed. Advances in neurobehavioral toxicology: applications in environmental and occupational health. Boca Raton, FL: CRC Press, 1990:203–23.
Benton A. Contributions to neuropsychological assessment. New York, NY: Oxford University Press, 1983.
Wechsler D. The Wechsler Adult Intelligence Scale–Revised manual. New York, NY: The Psychological Corporation, 1981.
10.1037/h0058244 Fleischman EA. Dimensional analysis of psychomotor abilities. J Exp Psychol1954;48:437–54.
10.1037/0021-843X.88.2.174 Radloff LS, Rae DS. Susceptibility and precipitating factors in depression: sex differences and similarities. J Abnorm Psychol1979;88:174–81.
10.1001/archneur.1977.00500210058010 Haaland KY, Cleeland CS, Carr D. Motor performance after unilateral hemisphere damage in patients with tumor. Arch Neurol1977;34:556–9.
10.1111/j.1745-3984.1989.tb00314.x Raven J. The Raven Progressive Matrices: a review of national norming studies and ethnic and socio-economic variation within the United States. J Educ Meas1989;16:1–16.
Arezzo JC. Quantitative sensory testing of vibration threshold–Vibratron II. Rationale and methods. Clifton, NJ: Physitemp Instruments, Inc, 1992.
10.1016/S0363-5023(84)80146-X Mathiowetz V, Weber K, Volland G, et al. Reliability and validity of grip and pinch strength evaluations. J Hand Surg [Am]1984;9:222–6.
10.1016/S0022-3476(82)80175-3 Thomas WJ, Collins TM. Comparison of venipuncture blood counts with microcapillary measurements in screening for anemia in one-year-old infants. J Pediatr1982;101:32–5.
10.1016/0009-8981(73)90466-X Heinegard D, Tiderstrom G. Determination of serum creatinine by a direct colorimetric method. Clin Chim Acta1973;43:305–10.
Kneip TJ, Crable JV. Methods for biological monitoring: a manual for assessing human exposure to hazardous substances. Washington, DC: American Public Health Association, 1988:199–201.
10.1007/978-1-4899-1268-8_66 Todd AC, McNeill FE. In vivo measurements of lead in bone using a Cd spot source. In: Human body composition studies. New York, NY: Plenum Press, 1993:299–302.
10.1016/S0013-9351(05)80073-8 Todd AC, McNeill FE, Palethorpe JE, et al. In vivo x-ray fluorescence of lead in bone using K x-ray excitation with 109Cd sources: radiation dosimetry studies. Environ Res1992;57:117–32.
10.1136/oem.56.1.22 Schwartz BS, Stewart WF, Todd AC, et al. Predictors of DMSA-chelatable lead levels and bone lead levels in organolead manufacturing workers. Occup Environ Med1999;56:22–9.
10.1088/0031-9155/40/9/007 Kim R, Aro A, Rotnitzky A, et al. K x-ray fluorescence measurements of bone lead concentration: the analysis of low-level data. Phys Med Biol1995;40:1475–85.
10.1016/S0584-8547(99)00007-5 Parsons PJ, Slavin W. Electrothermal atomization atomic absorption spectrometry for the determination of lead in urine: results of an interlaboratory study. Spectrochim Acta Part B1999;54:853–64.
10.1136/oem.52.1.13 Lee B-K, Schwartz BS, Stewart W, et al. Urinary lead excretion after DMSA and EDTA: evidence for differential access to lead storage sites. Occup Environ Med1995;52:13–19.
10.1136/oem.54.4.241 Schwartz BS, Lee B-K, Stewart W, et al. δ-Aminolevulinic acid dehydratase genotype modifies 4-hour urinary lead excretion after oral administration of dimercaptosuccinic acid. Occup Environ Med1997;54:241–6.
10.1097/00000441-199304000-00008 Batuman V. Lead nephropathy, gout, and hypertension. Am J Med Sci1993;305:241–7.
10.1136/oem.46.10.698 Stollery BT, Banks HA, Broadbent DE, et al. Cognitive functioning in lead workers. Br J Ind Med1989;46:698–707.
10.1037/0894-4105.10.1.120 Ingraham LJ, Aiken CB. An empirical approach to determining criteria for abnormality in test batteries with multiple measures. Neuropsychology1996;10:120–4.
10.1080/01621459.1979.10481038 Cleveland WS. Robust locally weighted regression and smoothing scatterplots. J Am Stat Assoc1979;74:829–36.
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