최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Biomaterials, v.259, 2020년, pp.120265 -
Park, Jongjin (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) , Lee, Na Geum (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) , Oh, Mihee (Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) , Song, Jinhoi (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) , Kim, Wooil (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) , Kwon, Min-Gi (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) , Kim, Seul Gi (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology) , Han, Baek Soo , Bae, Kwang-Hee , Lee, Dong Gwang , Lee, Sang-Hyun , Park, Jong-Gil , Kim, Jae Ho , Lee, Jangwook , Min, Jeong-Ki
Abstract The self-renewal properties of human pluripotent stem cells (hPSCs) contribute to their efficacy in tissue regeneration applications yet increase the likelihood of teratoma formation, thereby limiting their clinical utility. To address this issue, we developed a tool to specifically target...
Nat. Rev. Mol. Cell Biol. Trounson 17 3 194 2016 10.1038/nrm.2016.10 Pluripotent stem cells progressing to the clinic
Nat. Rev. Canc. Ben-David 11 4 268 2011 10.1038/nrc3034 The tumorigenicity of human embryonic and induced pluripotent stem cells
J. Biol. Chem. Peterson 289 8 4578 2014 10.1074/jbc.R113.516419 Genomic instability in pluripotent stem cells: implications for clinical applications
Proc. Natl. Acad. Sci. Unit. States Am. Lee 110 35 E3281 2013 10.1073/pnas.1303669110 Inhibition of pluripotent stem cell-derived teratoma formation by small molecules
Molecules Zhao 17 6 6196 2012 10.3390/molecules17066196 Embryonic stem cell markers
Differentiation Varlakhanova 80 1 9 2010 10.1016/j.diff.2010.05.001 Myc maintains embryonic stem cell pluripotency and self-renewal
Stem Cell Rev. Riekstina 5 4 378 2009 10.1007/s12015-009-9094-9 Embryonic stem cell marker expression pattern in human mesenchymal stem cells derived from bone marrow, adipose tissue, heart and dermis
Tohyama 163 2017 Purification of Pluripotent Stem Cell-Derived Cardiomyocytes for Safe Cardiac Regeneration, Cardiac Regeneration
Cell. Mol. Life Sci. Jeong 74 14 2601 2017 10.1007/s00018-017-2486-0 Technical approaches to induce selective cell death of pluripotent stem cells
Bioorg. Med. Chem. Lett. Bouchard 24 23 5357 2014 10.1016/j.bmcl.2014.10.021 Antibody-drug conjugates-a new wave of cancer drugs
Clin. Canc. Res. Nitiss 20 18 4737 2014 10.1158/1078-0432.CCR-14-0821 Twisting and ironing: doxorubicin cardiotoxicity by mitochondrial DNA damage
Annu. Rev. Med. Sievers 64 15 2013 10.1146/annurev-med-050311-201823 Antibody-drug conjugates in cancer therapy
Angew Chem. Int. Ed. Engl. Chari 53 15 3796 2014 10.1002/anie.201307628 Antibody-drug conjugates: an emerging concept in cancer therapy
J. Proteome Res. Dormeyer 7 7 2936 2008 10.1021/pr800056j Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells
Stem Cell Rep. Park 11 1 115 2018 10.1016/j.stemcr.2018.05.009 DSG2 is a functional cell surface marker for identification and isolation of human pluripotent stem cells
Nat. Biotechnol. Junutula 26 8 925 2008 10.1038/nbt.1480 Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
Biochim. Biophys. Acta Rev. Canc Yang 1845 1 84 2014 10.1016/j.bbcan.2013.12.002 Doxorubicin, DNA torsion, and chromatin dynamics
Nat. Commun. Pang 4 1908 2013 10.1038/ncomms2921 Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin
Biotechnol. Adv. Liu 32 4 693 2014 10.1016/j.biotechadv.2013.11.009 pH-sensitive nano-systems for drug delivery in cancer therapy
J. Contr. Release Yoo 68 3 419 2000 10.1016/S0168-3659(00)00280-7 In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin-PLGA conjugates
Exp. Cell Res. Gamen 258 1 223 2000 10.1006/excr.2000.4924 Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes ΔΨm loss, caspase-9 activity, and apoptosis in jurkat cells
Cell Death Differ. Cuvillier 8 162 2001 10.1038/sj.cdd.4400793 Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells
J. Biol. Chem. Wang 279 24 25535 2004 10.1074/jbc.M400944200 Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms: intermediacy of H(2)O(2)- and p53-dependent pathways
Life Sci. Mizutani 76 13 1439 2005 10.1016/j.lfs.2004.05.040 Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide
Cell Takahashi 131 5 861 2007 10.1016/j.cell.2007.11.019 Induction of pluripotent stem cells from adult human fibroblasts by defined factors
Science Yu 318 5858 1917 2007 10.1126/science.1151526 Induced pluripotent stem cell lines derived from human somatic cells
Ann. Med. Liew 37 7 521 2005 10.1080/07853890500379463 Human embryonic stem cells: possibilities for human cell transplantation
Stem Cell Rep. Avior 4 6 967 2015 10.1016/j.stemcr.2015.05.006 TeratoScore: assessing the differentiation potential of human pluripotent stem cells by quantitative expression analysis of teratomas
Stem Cell. Schuldiner 21 3 257 2003 10.1634/stemcells.21-3-257 Selective ablation of human embryonic stem cells expressing a “suicide” gene
Mol. Ther. Zhong 19 9 1667 2011 10.1038/mt.2011.51 Safeguarding nonhuman primate iPS cells with suicide genes
Biomaterials Chen 34 6 1701 2013 10.1016/j.biomaterials.2012.11.018 Suicide gene-mediated ablation of tumor-initiating mouse pluripotent stem cells
PloS One Richards 9 3 2014 10.1371/journal.pone.0085039 A new class of pluripotent stem cell cytotoxic small molecules
Sci. Rep. Vazquez-Martin 2 964 2012 10.1038/srep00964 Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency
Stem Cell Rev. Fong 5 1 72 2009 10.1007/s12015-009-9054-4 Separation of SSEA-4 and TRA-1-60 labelled undifferentiated human embryonic stem cells from a heterogeneous cell population using magnetic-activated cell sorting (MACS) and fluorescence-activated cell sorting (FACS)
Target. Oncol. Dancey 4 3 201 2009 10.1007/s11523-009-0119-8 Imaging in targeted delivery of therapy to cancer
Adv. Drug Deliv. Rev. Daugherty 58 5 686 2006 10.1016/j.addr.2006.03.011 Formulation and delivery issues for monoclonal antibody therapeutics
Schliemann 201 2010 Antibody-based Vascular Tumor Targeting, Angiogenesis Inhibition
Nat. Commun. Ben-David 4 1992 2013 10.1038/ncomms2992 Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells
Stem Cell Rep. Tateno 4 5 811 2015 10.1016/j.stemcr.2015.02.016 Elimination of tumorigenic human pluripotent stem cells by a recombinant lectin-toxin fusion protein
Stem Cell. Choo 26 6 1454 2008 10.1634/stemcells.2007-0576 Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin‐like protein‐1
Clin. Canc. Res. Sapra 11 14 5257 2005 10.1158/1078-0432.CCR-05-0204 Anti-CD74 antibody-doxorubicin conjugate, IMMU-110, in a human multiple myeloma xenograft and in monkeys
Oncol. Song 9 3 263 2014 Anti-Sp17 monoclonal antibody-doxorubicin conjugates as molecularly targeted chemotherapy for ovarian carcinoma, Target
Colloids Surf., B McKee 159 62 2017 10.1016/j.colsurfb.2017.07.051 Advances and challenges in stem cell culture
J. Histochem. Cytochem. Suzuki 58 8 721 2010 10.1369/jhc.2010.955609 The neural stem/progenitor cell marker nestin is expressed in proliferative endothelial cells, but not in mature vasculature
Exp. Cell Res. Roberts 317 20 2814 2011 10.1016/j.yexcr.2011.09.003 Desmosome dynamics in migrating epithelial cells requires the actin cytoskeleton
Am. J. Pathol. Kountikov 185 3 617 2015 10.1016/j.ajpath.2014.10.025 A spontaneous deletion within the desmoglein 3 extracellular domain of mice results in hypomorphic protein expression, immunodeficiency, and a wasting disease phenotype
Nat. Rev. Drug Discov. Beck 16 5 315 2017 10.1038/nrd.2016.268 Strategies and challenges for the next generation of antibody-drug conjugates
Protein Cell Wang 9 1 63 2018 10.1007/s13238-017-0473-8 IgG Fc engineering to modulate antibody effector functions
Stem Cell. Liu 34 10 2471 2016 10.1002/stem.2431 Distinct responses of stem cells to telomere uncapping-a potential strategy to improve the safety of cell therapy
해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.