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NTIS 바로가기Journal of cell science, v.133 no.20, 2020년, pp.jcs244731 - jcs244731
Boscher, Julie , Guinard, Ines , Eckly, Anita , Lanza, Francois , Léon, Catherine
The main function of blood platelets is to ensure hemostasis and prevent hemorrhages. The 1011 platelets needed daily are produced in a well-orchestrated process. However, this process is not yet fully understood and in vitro platelet production is still inefficient. Platelets are produced in the bo...
Haematologica Abbonante 102 1150 2017 10.3324/haematol.2016.161562 A new path to platelet production through matrix sensing
Blood Aguilar 128 2022 2016 10.1182/blood-2016-02-699959 Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation
Nature Akashi 404 193 2000 10.1038/35004599 A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
Front. Cardiovasc. Med. Almazni 6 80 2019 10.3389/fcvm.2019.00080 Inherited thrombocytopenia: update on genes and genetic variants which may be associated with bleeding
Arch. Pathol. Anat. Aschoff 134 11 1893 10.1007/BF01924893 Ueber capillare embolie von riesenkernhaltigen zellen
Nat. Med. Avecilla 10 64 2004 10.1038/nm973 Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
J. Clin. Invest. Avraham 91 2378 1993 10.1172/JCI116470 Characterization of adhesive interactions between human endothelial cells and megakaryocytes
Balduini 2008 10.1111/j.1538-7836.2008.03132.x
Platelets Balduini 28 3 2017 10.3109/09537104.2016.1171835 Inherited thrombocytopenias-recent advances in clinical and molecular aspects
Curr. Biol. Basant 28 R570 2018 10.1016/j.cub.2018.03.045 Spatiotemporal regulation of RhoA during cytokinesis
Am. J. Anat. Becker 145 183 1976 10.1002/aja.1001450204 The transmural passage of blood cells into myeloid sinusoids and the entry of platelets into the sinusoidal circulation; a scanning electron microscopic investigation
Blood Begonja 126 80 2015 10.1182/blood-2014-07-587600 FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets
J. Ultrastruct. Res. Behnke 24 412 1968 10.1016/s0022-5320(68)80046-2 An electron microscope study of the megacaryocyte of the rat bone marrow. I. The development of the demarcation membrane system and the platelet surface coat
Eur. J. Haematol. Suppl. Behnke 60 3 1998 10.1111/j.1600-0609.1998.tb01052.x From megakaryocytes to platelets: platelet morphogenesis takes place in the bloodstream
Growth Factors Behrens 36 89 2018 10.1080/08977194.2018.1498487 Cytokine control of megakaryopoiesis
Blood Bender 125 860 2015 10.1182/blood-2014-09-600858 Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein
Platelets Biljak 22 466 2011 10.3109/09537104.2011.573887 Platelet count, mean platelet volume and smoking status in stable chronic obstructive pulmonary disease
Haematologica Bornert haematol.2019.239111 2020 10.3324/haematol.2019.239111 Cytoskeletal-based mechanisms differently regulate in vivo and in vitro proplatelet formation
Am. J. Clin. Pathol. Broghamer 76 178 1981 10.1093/ajcp/76.2.178 Megakaryocytes in renal glomeruli
Blood Adv. Brouard 1 1854 2017 10.1182/bloodadvances.2016003541 A unique microenvironment in the developing liver supports the expansion of megakaryocyte progenitors
Life Sci. Alliance Brown 1 e201800061 2018 10.26508/lsa.201800061 Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels
Nature Carrelha 554 106 2018 10.1038/nature25455 Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells
Blood Chang 109 4229 2007 10.1182/blood-2006-04-020024 Proplatelet formation is regulated by the Rho/ROCK pathway
Blood Chen 110 171 2007 10.1182/blood-2007-02-071589 The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway
Blood Chen 122 1695 2013 10.1182/blood-2013-03-484550 Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling
Haematologica Daly 96 10 2011 10.3324/haematol.2010.035287 Determinants of platelet count in humans
Deutsch 2013 10.1111/bjh.12328 Advances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside
Blood Di Buduo 125 2254 2015 10.1182/blood-2014-08-595561 Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies
Sci. Rep. Do Sacramento 10 914 2020 10.1038/s41598-020-57754-9 Functional properties of human platelets derived in vitro from CD34(+) cells
Blood Dunois-Larde 114 1875 2009 10.1182/blood-2009-03-209205 Exposure of human megakaryocytes to high shear rates accelerates platelet production
Nat. Commun. Dutting 8 15838 2017 10.1038/ncomms15838 A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis
J. Thromb. Haemost. Eckly 8 2243 2010 10.1111/j.1538-7836.2010.04009.x Proplatelet formation deficit and megakaryocyte death contribute to thrombocytopenia in Myh9 knockout mice
Blood Eckly 123 921 2014 10.1182/blood-2013-03-492330 Biogenesis of the demarcation membrane system (DMS) in megakaryocytes
J. Thromb. Haemost. Eckly 2020 10.1111/jth.15024 Megakaryocytes use in vivo podosome-like structures working collectively to penetrate the endothelial barrier of bone marrow sinusoids
Dev. Cell Gao 22 573 2012 10.1016/j.devcel.2011.12.019 Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes
Cell Cycle Geddis 6 455 2007 10.4161/cc.6.4.3836 Endomitotic megakaryocytes that form a bipolar spindle exhibit cleavage furrow ingression followed by furrow regression
J. Thromb. Haemost. Ghalloussi 17 1430 2019 10.1111/jth.14544 New insights into cytoskeletal remodeling during platelet production
Cell Stem Cell Haas 17 422 2015 10.1016/j.stem.2015.07.007 Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors
J. Exp. Med. Hamada 188 539 1998 10.1084/jem.188.3.539 Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation
Br. J. Haematol. Hitchcock 165 259 2014 10.1111/bjh.12772 Thrombopoietin from beginning to end
J. Exp. Med. Howell 65 177 1937 10.1084/jem.65.2.177 The production of blood platelets in the lungs
J. Cell. Biochem. Huang 107 857 2009 10.1002/jcb.22184 Common features of megakaryocytes and hematopoietic stem cells: what's the connection?
Mol. Cell. Biol. Huang 29 4103 2009 10.1128/MCB.00090-09 Differentiation-dependent interactions between RUNX-1 and FLI-1 during megakaryocyte development
J. Cell Biol. Italiano 147 1299 1999 10.1083/jcb.147.6.1299 Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes
Cell Ito 174 636 2018 10.1016/j.cell.2018.06.011 Turbulence activates platelet biogenesis to enable clinical scale ex vivo production
Science Junt 317 1767 2007 10.1126/science.1146304 Dynamic visualization of thrombopoiesis within bone marrow
Acta Haematol. Kallinikos-Maniatis 42 330 1969 10.1159/000208817 Megakaryocytes and platelets in central venous and arterial blood
Kanaji 2018 10.1073/pnas.1807000115
Int. J. Hematol. Kosaki 81 208 2005 10.1532/IJH97.04177 In vivo platelet production from mature megakaryocytes: does platelet release occur via proplatelets?
Thromb. Haemost. Kowata 112 743 2014 10.1160/TH14-02-0123 Platelet demand modulates the type of intravascular protrusion of megakaryocytes in bone marrow
Exp. Hematol. Lee 42 332 2014 10.1016/j.exphem.2014.02.002 Biomanufacture of human platelets for transfusion: rationale and approaches
Nature Lefrancais 544 105 2017 10.1038/nature21706 The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors
Leiva 2018 10.1002/ajh.25008
Blood Leon 119 3333 2012 10.1182/blood-2011-08-373811 Romiplostim administration shows reduced megakaryocyte response-capacity and increased myelofibrosis in a mouse model of MYH9-RD
Haematologica Leon 101 896 2016 10.3324/haematol.2015.139394 The contribution of mouse models to the understanding of constitutional thrombocytopenia
Eur. J. Haematol. Levine 51 233 1993 10.1111/j.1600-0609.1993.tb00637.x Circulating megakaryocytes: delivery of large numbers of intact, mature megakaryocytes to the lungs
Br. J. Haematol. Li 155 298 2011 10.1111/j.1365-2141.2011.08859.x microRNA regulation in megakaryocytopoiesis
Blood Lordier 116 2345 2010 10.1182/blood-2010-01-265785 Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process
EMBO J. Mancini 31 351 2012 10.1038/emboj.2011.390 FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors
J. Immunol. Margraf 203 2357 2019 10.4049/jimmunol.1900899 Platelets in inflammation and resolution
Biol. Lett. Martin 15 20190374 2019 10.1098/rsbl.2019.0374 The origin of platelets enabled the evolution of eutherian placentation
Blood Mattia 99 888 2002 10.1182/blood.V99.3.888 Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release
Exp. Hematol. Mazzi 57 1 2018 10.1016/j.exphem.2017.10.001 Megakaryocyte and polyploidization
Malara 2011 10.1182/blood-2011-04-345876
Thromb. Res. McNicol 95 1 1999 10.1016/S0049-3848(99)00015-8 Platelet dense granules: structure, function and implications for haemostasis
Haemophilia Melazzini 23 673 2017 10.1111/hae.13255 Bleeding is not the main clinical issue in many patients with inherited thrombocytopaenias
J. Biol. Chem. Meyer 272 2914 1997 10.1074/jbc.272.5.2914 Identification of the region in actin-binding protein that binds to the cytoplasmic domain of glycoprotein IBalpha
Nat. Commun. Moreau 7 11208 2016 10.1038/ncomms11208 Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming
Cell Stem Cell Nakamura 14 535 2014 10.1016/j.stem.2014.01.011 Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells
Arterioscler. Thromb. Vasc. Biol. Noetzli 39 1288 2019 10.1161/ATVBAHA.119.312129 New insights into the differentiation of megakaryocytes from hematopoietic progenitors
Semin. Thromb. Hemost. Nurden 40 577 2014 10.1055/s-0034-1383826 Platelet membrane glycoproteins: a historical review
Front. Biosci. Nurden 13 3532 2008 10.2741/2947 Platelets and wound healing
Blood Odell 32 102 1968 10.1182/blood.V32.1.102.102 Polyploidy and maturation of rat megakaryocytes
Exp. Hematol. Ouzegdouh 63 22 2018 10.1016/j.exphem.2018.04.001 The physical and cellular conditions of the human pulmonary circulation enable thrombopoiesis
Front. Immunol. Palacios-Acedo 10 1805 2019 10.3389/fimmu.2019.01805 Platelets, thrombo-inflammation, and cancer: collaborating with the enemy
Blood Patel-Hett 111 4605 2008 10.1182/blood-2007-10-118844 Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules
Scand. J. Haematol. Pedersen 21 369 1978 10.1111/j.1600-0609.1978.tb00381.x Occurrence of megakaryocytes in various vessels and their retention in the pulmonary capillaries in man
Blood Potts 124 2725 2014 10.1182/blood-2014-02-559468 A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo
Blood Psaila 133 1427 2019 10.1182/blood-2018-11-835371 Single-cell approaches reveal novel cellular pathways for megakaryocyte and erythroid differentiation
Blood Radley 60 213 1982 10.1182/blood.V60.1.213.213 The demarcation membrane system of the megakaryocyte: a misnomer?
Blood Radley 56 996 1980 10.1182/blood.V56.6.996.996 The mechanism of platelet release
Platelets Raghuwanshi 30 809 2019 10.1080/09537104.2018.1528343 MicroRNA function in megakaryocytes
J. Cell. Physiol. Ravid 190 7 2002 10.1002/jcp.10035 Roads to polyploidy: the megakaryocyte example
Nature Rodriguez-Fraticelli 553 212 2018 10.1038/nature25168 Clonal analysis of lineage fate in native haematopoiesis
Nature Sanjuan-Pla 502 232 2013 10.1038/nature12495 Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
Blood Schachtner 121 2542 2013 10.1182/blood-2012-07-443457 Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane
Blood Schmaier 118 3661 2011 10.1182/blood-2011-02-338244 Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular disease
Blood Schulze 107 3868 2006 10.1182/blood-2005-07-2755 Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis
F1000Res. Sharda 7 236 2018 10.12688/f1000research.13283.1 The life cycle of platelet granules
Proc. Natl. Acad. Sci. USA Shin 108 11458 2011 10.1073/pnas.1017474108 Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes
Cell Stem Cell Shin 14 81 2014 10.1016/j.stem.2013.10.009 Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells
Int. J. Lab. Hematol. Smock 36 269 2014 10.1111/ijlh.12214 Thrombocytopenia: an update
Spindler 2018 10.1182/blood-2018-01-829259
Nat. Commun. Stegner 8 127 2017 10.1038/s41467-017-00201-7 Thrombopoiesis is spatially regulated by the bone marrow vasculature
Blood Cells Stenberg 15 23 1989 Mechanisms of platelet production
Blood Strassel 127 2231 2016 10.1182/blood-2015-09-670208 Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets
Front. Med. (Lausanne) Strassel 5 239 2018 10.3389/fmed.2018.00239 On the way to in vitro platelet production
Life Sci. Alliance Strassel 2 e201900309 2019 10.26508/lsa.201900309 An essential role for alpha4A-tubulin in platelet biogenesis
J. Thromb. Haemost. Sugimoto 15 1717 2017 10.1111/jth.13736 Platelet production from induced pluripotent stem cells
J. Cell Sci. Tablin 97 59 1990 10.1242/jcs.97.1.59 Blood platelet formation in vitro. The role of the cytoskeleton in megakaryocyte fragmentation
Blood Tamura 127 1701 2016 10.1182/blood-2015-08-663708 Podoplanin-positive periarteriolar stromal cells promote megakaryocyte growth and proplatelet formation in mice by CLEC-2
Br. J. Haematol. Tavassoli 48 25 1981 10.1111/j.1365-2141.1981.00025.x Migration of entire megakaryocytes through the marrow--blood barrier
Med. Hypotheses Thachil 72 291 2009 10.1016/j.mehy.2008.09.045 The lung megakaryocytes and pulmonary fibrosis in systemic sclerosis
Platelets Thon 28 472 2017 10.1080/09537104.2016.1265922 Platelet bioreactor: accelerated evolution of design and manufacture
J. Thromb. Haemost. Tijssen 11 593 2013 10.1111/jth.12131 Transcription factors in late megakaryopoiesis and related platelet disorders
Thromb. Res. Trowbridge 28 461 1982 10.1016/0049-3848(82)90163-3 Evidence for a theory of physical fragmentation of megakaryocytes, implying that all platelets are produced in the pulmonary circulation
Platelets Vainchenker 31 707 2019 10.1080/09537104.2019.1667497 Megakaryocyte polyploidization: role in platelet production
Blood Vitrat 91 3711 1998 10.1182/blood.V91.10.3711 Endomitosis of human megakaryocytes are due to abortive mitosis
Cells Ward 9 894 2020 10.3390/cells9040894 Matrix mechanosensation in the erythroid and megakaryocytic lineages
Blood Adv. Weiss 3 33 2019 10.1182/bloodadvances.2018023804 microRNA-22 promotes megakaryocyte differentiation through repression of its target, GFI1
Blood Woolthuis 127 1242 2016 10.1182/blood-2015-07-607945 Hematopoietic stem/progenitor cell commitment to the megakaryocyte lineage
J. Morphol. Wright 21 263 1910 10.1002/jmor.1050210204 The histogenesis of the blood platelets
Cell Yamamoto 154 1112 2013 10.1016/j.cell.2013.08.007 Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells
Leuk. Lymphoma Yamauchi 15 253 1994 10.3109/10428199409049721 Pulmonary fibrosis with megakaryocytoid cell infiltration and chronic myelogenous leukemia
Am. J. Pathol. Zucker-Franklin 157 69 2000 10.1016/S0002-9440(10)64518-X Platelet production in the pulmonary capillary bed: new ultrastructural evidence for an old concept
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