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[해외논문] Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex 원문보기

Cell death and differentiation, v.27 no.11, 2020년, pp.3065 - 3081  

Seo, Jinho (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) ,  Seong, Daehyeon (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) ,  Nam, Young Woo (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) ,  Hwang, Chi Hyun (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) ,  Lee, Seung Ri (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) ,  Lee, Choong-Sil (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) ,  Jin, Young (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) ,  Lee, Han-Woong (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) ,  Oh, Doo-Byoung (Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea) ,  Vandenabeele, Peter (VIB-UGent Center for Inflammation Rese) ,  Song, Jaewhan

Abstract AI-Helper 아이콘AI-Helper

Necroptosis is a form of regulated cell death caused by formation of the necrosome complex. However, the factors modulating this process and the systemic pathophysiological effects of necroptosis are yet to be understood. Here, we identified that Beclin 1 functions as an anti-necroptosis factor by b...

참고문헌 (47)

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