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NTIS 바로가기Cell death and differentiation, v.27 no.11, 2020년, pp.3065 - 3081
Seo, Jinho (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) , Seong, Daehyeon (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) , Nam, Young Woo (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) , Hwang, Chi Hyun (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) , Lee, Seung Ri (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) , Lee, Choong-Sil (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) , Jin, Young (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) , Lee, Han-Woong (Department of Biochemistry, College of Life science and Biotechnology, Yonsei University, Seoul, Korea) , Oh, Doo-Byoung (Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea) , Vandenabeele, Peter (VIB-UGent Center for Inflammation Rese) , Song, Jaewhan
Necroptosis is a form of regulated cell death caused by formation of the necrosome complex. However, the factors modulating this process and the systemic pathophysiological effects of necroptosis are yet to be understood. Here, we identified that Beclin 1 functions as an anti-necroptosis factor by b...
1. Seo J Kim MW Bae KH Lee SC Song J Lee EW The roles of ubiquitination in extrinsic cell death pathways and its implications for therapeutics Biochem Pharmacol 2019 162 21 40 30452908
2. Cho YS Challa S Moquin D Genga R Ray TD Guildford M Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation Cell 2009 137 1112 23 19524513
3. He S Liang Y Shao F Wang X Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway Proc Natl Acad Sci USA 2011 108 20054 9 22123964
4. He S Wang L Miao L Wang T Du F Zhao L Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha Cell 2009 137 1100 11 19524512
5. Kaiser WJ Sridharan H Huang C Mandal P Upton JW Gough PJ Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL J Biol Chem 2013 288 31268 79 24019532
6. Rebsamen M Heinz LX Meylan E Michallet MC Schroder K Hofmann K DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB EMBO Rep 2009 10 916 22 19590578
7. Zhang DW Shao J Lin J Zhang N Lu BJ Lin SC RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis Science 2009 325 332 6 19498109
8. Chen X Li W Ren J Huang D He WT Song Y Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death Cell Res 2014 24 105 21 24366341
9. Cai Z Jitkaew S Zhao J Chiang HC Choksi S Liu J Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis Nat Cell Biol 2014 16 55 65 24316671
10. Chen W Zhou Z Li L Zhong CQ Zheng X Wu X Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling J Biol Chem 2013 288 16247 61 23612963
11. Wang H Sun L Su L Rizo J Liu L Wang LF Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3 Mol Cell 2014 54 133 46 24703947
12. Dondelinger Y Declercq W Montessuit S Roelandt R Goncalves A Bruggeman I MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates Cell Rep 2014 7 971 81 24813885
13. Quarato G Guy CS Grace CR Llambi F Nourse A Rodriguez DA Sequential engagement of distinct MLKL phosphatidylinositol-binding sites executes necroptosis Mol Cell 2016 61 589 601 26853145
15. Bertrand MJ Milutinovic S Dickson KM Ho WC Boudreault A Durkin J cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination Mol Cell 2008 30 689 700 18570872
16. Gerlach B Cordier SM Schmukle AC Emmerich CH Rieser E Haas TL Linear ubiquitination prevents inflammation and regulates immune signalling Nature 2011 471 591 6 21455173
17. Geng J Ito Y Shi L Amin P Chu J Ouchida AT Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis Nat Commun 2017 8 359 28842570
18. Menon MB Gropengiesser J Fischer J Novikova L Deuretzbacher A Lafera J p38(MAPK)/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection Nat Cell Biol 2017 19 1248 59 28920954
19. Jaco I Annibaldi A Lalaoui N Wilson R Tenev T Laurien L MK2 phosphorylates RIPK1 to prevent TNF-induced cell death Mol Cell 2017 66 698 710 28506461
20. Dondelinger Y Delanghe T Rojas-Rivera D Priem D Delvaeye T Bruggeman I MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death Nat Cell Biol 2017 19 1237 47 28920952
21. Lafont E Draber P Rieser E Reichert M Kupka S de Miguel D TBK1 and IKKepsilon prevent TNF-induced cell death by RIPK1 phosphorylation Nat Cell Biol 2018 20 1389 99 30420664
22. Xu D Jin T Zhu H Chen H Ofengeim D Zou C TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging Cell 2018 174 1477 91 30146158
23. Dondelinger Y Jouan-Lanhouet S Divert T Theatre E Bertin J Gough PJ NF-kappaB-independent role of IKKalpha/IKKbeta in preventing RIPK1 kinase-dependent apoptotic and necroptotic cell death during TNF signaling Mol Cell 2015 60 63 76 26344099
24. Seo J Lee EW Sung H Seong D Dondelinger Y Shin J CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3 Nat Cell Biol 2016 18 291 302 26900751
25. Choi SW Park HH Kim S Chung JM Noh HJ Kim SK PELI1 selectively targets kinase-active RIP3 for ubiquitylation-dependent proteasomal degradation Mol Cell 2018 70 920 35 29883609
26. Onizawa M Oshima S Schulze-Topphoff U Oses-Prieto JA Lu T Tavares R The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis Nat Immunol 2015 16 618 27 25939025
27. Petersen SL Chen TT Lawrence DA Marsters SA Gonzalvez F Ashkenazi A TRAF2 is a biologically important necroptosis suppressor Cell Death Differ 2015 22 1846 57 25882049
28. Li X Gong W Wang H Li T Attri KS Lewis RE O-GlcNAc transferase suppresses inflammation and necroptosis by targeting receptor-interacting serine/Threonine-Protein Kinase 3 Immunity 2019 50 1115 30995496
29. Wirawan E Lippens S Vanden Berghe T Romagnoli A Fimia GM Piacentini M Beclin1: a role in membrane dynamics and beyond Autophagy 2012 8 6 17 22170155
30. Menon MB Dhamija S Beclin 1 phosphorylation―at the center of autophagy regulation Front Cell Dev Biol 2018 6 137 30370269
31. Wirawan E Vande Walle L Kersse K Cornelis S Claerhout S Vanoverberghe I Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria Cell Death Dis 2010 1 e18 21364619
32. Luo S Rubinsztein DC Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL Cell Death Differ 2010 17 268 77 19713971
33. Song X Zhu S Chen P Hou W Wen Q Liu J AMPK-mediated BECN1 phosphorylation promotes ferroptosis by directly blocking system Xc(-) activity Curr Biol 2018 28 2388 99 30057310
34. Lee HY Kim J Quan W Lee JC Kim MS Kim SH Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis Autophagy 2016 12 1390 403 27337687
35. Seo J Lee EW Shin J Seong D Nam YW Jeong M K6 linked polyubiquitylation of FADD by CHIP prevents death inducing signaling complex formation suppressing cell death Oncogene 2018 37 4994 5006 29795330
36. Wu YT Tan HL Huang Q Kim YS Pan N Ong WY Autophagy plays a protective role during zVAD-induced necrotic cell death Autophagy 2008 4 457 66 18253089
37. Dovey CM Diep J Clarke BP Hale AT McNamara DE Guo H MLKL requires the inositol phosphate code to execute necroptosis Mol Cell 2018 70 936 48 29883610
38. Rodriguez DA Weinlich R Brown S Guy C Fitzgerald P Dillon CP Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis Cell Death Differ 2016 23 76 88 26024392
39. Zhao J Jitkaew S Cai Z Choksi S Li Q Luo J Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis Proc Natl Acad Sci USA 2012 109 5322 7 22421439
40. Murphy JM Czabotar PE Hildebrand JM Lucet IS Zhang JG Alvarez-Diaz S The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism Immunity 2013 39 443 53 24012422
41. Sun L Wang H Wang Z He S Chen S Liao D Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase Cell 2012 148 213 27 22265413
42. Feldmann F Schenk B Martens S Vandenabeele P Fulda S Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells Oncotarget 2017 8 68208 20 28978109
43. Safferthal C Rohde K Fulda S Therapeutic targeting of necroptosis by Smac mimetic bypasses apoptosis resistance in acute myeloid leukemia cells Oncogene 2017 36 1487 502 27869161
44. Steinhart L Belz K Fulda S Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis Cell Death Dis 2013 4 e802 24030154
45. Hildebrand JM Tanzer MC Lucet IS Young SN Spall SK Sharma P Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death Proc Natl Acad Sci USA 2014 111 15072 7 25288762
46. Petrie EJ Sandow JJ Jacobsen AV Smith BJ Griffin MDW Lucet IS Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis Nat Commun 2018 9 2422 29930286
47. Najafov A Mookhtiar AK Luu HS Ordureau A Pan H Amin PP TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL Mol Cell 2019 75 457 68 31230815
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