참고문헌 (131)

1. Adey NB , Huang L , Ormonde PA , Baumgard ML , Pero R , Byreddy DV , Tavtigian SV , Bartel PL ( 2000 ) Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding . Can Res 60 : 35 ？ 37 

2. Alfadhel M , Nashabat M , Qahtani HA , Alfares A , Mutairi FA , Shaalan HA , Douglas GV , Wierenga K , Juusola J , Alrifai MT et al ( 2016 ) Mutation in SLC6A9 encoding a glycine transporter causes a novel form of non­ketotic hyperglycinemia in humans . Hum Genet 135 : 1263 ？ 1268 27481395 

   상세보기

3. Anas MK , Lee MB , Zhou C , Hammer MA , Slow S , Karmouch J , Liu XJ , Broer S , Lever M , Baltz JM ( 2008 ) SIT1 is a betaine/proline transporter that is activated in mouse eggs after fertilization and functions until the 2­cell stage . Development 135 : 4123 ？ 4130 19029042 

4. Anders S , Pyl PT , Huber W ( 2015 ) HTSeq？a Python framework to work with high­throughput sequencing data . Bioinformatics 31 : 166 ？ 169 25260700 

   상세보기

5. Backman SA , Stambolic V , Suzuki A , Haight J , Elia A , Pretorius J , Tsao MS , Shannon P , Bolon B , Ivy GO et al ( 2001 ) Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte­Duclos disease . Nat Genet 29 : 396 ？ 403 11726926 

   상세보기

6. Bassi C , Ho J , Srikumar T , Dowling RJ , Gorrini C , Miller SJ , Mak TW , Neel BG , Raught B , Stambolic V ( 2013 ) Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress . Science 341 : 395 ？ 399 23888040 

   상세보기

7. Betz H , Gomeza J , Armsen W , Scholze P , Eulenburg V ( 2006 ) Glycine transporters: essential regulators of synaptic transmission . Biochem Soc Trans 34 : 55 ？ 58 16417482 

   상세보기

8. Bolger AM , Lohse M , Usadel B ( 2014 ) Trimmomatic: a flexible trimmer for Illumina sequence data . Bioinformatics 30 : 2114 ？ 2120 24695404 

   상세보기

9. Bonifant CL , Kim JS , Waldman T ( 2007 ) NHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN . J Cell Biochem 102 : 878 ？ 885 17786934 

   상세보기

10. Brennand KJ , Simone A , Jou J , Gelboin­Burkhart C , Tran N , Sangar S , Li Y , Mu Y , Chen G , Yu D et al ( 2011 ) Modelling schizophrenia using human induced pluripotent stem cells . Nature 473 : 221 ？ 225 21490598 

    상세보기

11. Broer S , Bailey CG , Kowalczuk S , Ng C , Vanslambrouck JM , Rodgers H , Auray­Blais C , Cavanaugh JA , Broer A , Rasko JE ( 2008 ) Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters . J Clin Invest 118 : 3881 ？ 3892 19033659 

    상세보기

12. Broer A , Balkrishna S , Kottra G , Davis S , Oakley A , Broer S ( 2009 ) Sodium translocation by the iminoglycinuria associated imino transporter (SLC6A20) . Mol Membr Biol 26 : 333 ？ 346 19657969 

    상세보기

13. Broer S , Gether U ( 2012 ) The solute carrier 6 family of transporters . Br J Pharmacol 167 : 256 ？ 278 22519513 

14. Cabib S , Puglisi­Allegra S ( 1985 ) Different effects of apomorphine on climbing behavior and locomotor activity in three strains of mice . Pharmacol Biochem Behav 23 : 555 ？ 557 4070332 

    상세보기

15. Chen L , Muhlhauser M , Yang CR ( 2003 ) Glycine tranporter­1 blockade potentiates NMDA­mediated responses in rat prefrontal cortical neurons in vitro and in vivo . J Neurophysiol 89 : 691 ？ 703 12574447 

    상세보기

16. Clark JA , Deutch AY , Gallipoli PZ , Amara SG ( 1992 ) Functional expression and CNS distribution of a beta­alanine­sensitive neuronal GABA transporter . Neuron 9 : 337 ？ 348 1497897 

17. Clark JA , Amara SG ( 1994 ) Stable expression of a neuronal gamma­aminobutyric acid transporter, GAT­3, in mammalian cells demonstrates unique pharmacological properties and ion dependence . Mol Pharmacol 46 : 550 ？ 557 7935337 

    상세보기

18. Clipperton­Allen AE , Page DT ( 2014 ) Pten haploinsufficient mice show broad brain overgrowth but selective impairments in autism­relevant behavioral tests . Hum Mol Genet 23 : 3490 ？ 3505 24497577 

    상세보기

19. Crespi B , Stead P , Elliot M ( 2010 ) Evolution in health and medicine Sackler colloquium: comparative genomics of autism and schizophrenia . Proc Natl Acad Sci USA 107 ( Suppl 1 ): 1736 ？ 1741 19955444 

20. Cubelos B , Gimenez C , Zafra F ( 2005 ) Localization of the GLYT1 glycine transporter at glutamatergic synapses in the rat brain . Cereb Cortex 15 : 448 ？ 459 15749988 

    상세보기

21. Cupolillo D , Hoxha E , Faralli A , De Luca A , Rossi F , Tempia F , Carulli D ( 2016 ) Autistic­like traits and cerebellar dysfunction in purkinje cell PTEN knock­out mice . Neuropsychopharmacology 41 : 1457 ？ 1466 26538449 

    상세보기

22. Dahlin A , Royall J , Hohmann JG , Wang J ( 2009 ) Expression profiling of the solute carrier gene family in the mouse brain . J Pharmacol Exp Ther 329 : 558 ？ 570 19179540 

    상세보기

23. Deacon RM ( 2006 ) Digging and marble burying in mice: simple methods for in vivo identification of biological impacts . Nat Protoc 1 : 122 ？ 124 17406223 

    상세보기

24. Endersby R , Baker SJ ( 2008 ) PTEN signaling in brain: neuropathology and tumorigenesis . Oncogene 27 : 5416 ？ 5430 18794877 

    상세보기

25. Engelhardt B , Sorokin L ( 2009 ) The blood­brain and the blood­cerebrospinal fluid barriers: function and dysfunction . Semin Immunopathol 31 : 497 ？ 511 19779720 

    상세보기

26. Engert F , Bonhoeffer T ( 1999 ) Dendritic spine changes associated with hippocampal long­term synaptic plasticity . Nature 399 : 66 ­ 69 . 10331391 

    상세보기

27. Eulenburg V , Retiounskaia M , Papadopoulos T , Gomeza J , Betz H ( 2010 ) Glial glycine transporter 1 function is essential for early postnatal survival but dispensable in adult mice . Glia 58 : 1066 ？ 1073 20468048 

    상세보기

28. Fang D , Hawke D , Zheng Y , Xia Y , Meisenhelder J , Nika H , Mills GB , Kobayashi R , Hunter T , Lu Z ( 2007 ) Phosphorylation of beta­catenin by AKT promotes beta­catenin transcriptional activity . J Biol Chem 282 : 11221 ？ 11229 17287208 

29. Fricano­Kugler CJ , Getz SA , Williams MR , Zurawel AA , DeSpenza Jr T , Frazel PW , Li M , O'Malley AJ , Moen EL , Luikart BW ( 2018 ) Nuclear excluded autism­associated phosphatase and tensin homolog mutations dysregulate neuronal growth . Biol Psychiatry 84 : 265 ？ 277 29373119 

    상세보기

30. Gabernet L , Pauly­Evers M , Schwerdel C , Lentz M , Bluethmann H , Vogt K , Alberati D , Mohler H , Boison D ( 2005 ) Enhancement of the NMDA receptor function by reduction of glycine transporter­1 expression . Neurosci Lett 373 : 79 ？ 84 15555781 

31. Gil A , Andres­Pons A , Fernandez E , Valiente M , Torres J , Cervera J , Pulido R ( 2006 ) Nuclear localization of PTEN by a Ran­dependent mechanism enhances apoptosis: Involvement of an N­terminal nuclear localization domain and multiple nuclear exclusion motifs . Mol Biol Cell 17 : 4002 ？ 4013 16807353 

    상세보기

32. Gil A , Andres­Pons A , Pulido R ( 2007 ) Nuclear PTEN: a tale of many tails . Cell Death Differ 14 : 395 ？ 399 17186024 

    상세보기

33. Goh CP , Putz U , Howitt J , Low LH , Gunnersen J , Bye N , Morganti­Kossmann C , Tan SS ( 2014 ) Nuclear trafficking of Pten after brain injury leads to neuron survival not death . Exp Neurol 252 : 37 ？ 46 24275527 

    상세보기

34. Golden AP , Li N , Chen Q , Lee T , Nevill T , Cao X , Johnson J , Erdemli G , Ionescu­Zanetti C , Urban L et al ( 2011 ) IonFlux: a microfluidic patch clamp system evaluated with human Ether­a­go­go related gene channel physiology and pharmacology . Assay Drug Dev Technol 9 : 608 ？ 619 21561375 

    상세보기

35. Gomeza J , Hulsmann S , Ohno K , Eulenburg V , Szoke K , Richter D , Betz H ( 2003a ) Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition . Neuron 40 : 785 ？ 796 14622582 

    상세보기

36. Gomeza J , Ohno K , Betz H ( 2003b ) Glycine transporter isoforms in the mammalian central nervous system: structures, functions and therapeutic promises . Curr Opin Drug Discov Devel 6 : 675 ？ 682 

    상세보기

37. Gomeza J , Ohno K , Hulsmann S , Armsen W , Eulenburg V , Richter DW , Laube B , Betz H ( 2003c ) Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality . Neuron 40 : 797 ？ 806 14622583 

    상세보기

38. Gray JA , Nicoll RA ( 2012 ) Thinking outside the synapse: glycine at extrasynaptic NMDA receptors . Cell 150 : 455 ？ 456 22863001 

    상세보기

39. Hall CN , Reynell C , Gesslein B , Hamilton NB , Mishra A , Sutherland BA , O'Farrell FM , Buchan AM , Lauritzen M , Attwell D ( 2014 ) Capillary pericytes regulate cerebral blood flow in health and disease . Nature 508 : 55 ？ 60 24670647 

40. Harvey RJ , Yee BK ( 2013 ) Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain . Nat Rev Drug Discovery 12 : 866 ？ 885 24172334 

41. Hayashi Y , Shi SH , Esteban JA , Piccini A , Poncer JC , Malinow R ( 2000 ) Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction . Science 287 : 2262 ？ 2267 10731148 

    상세보기

42. He L , Vanlandewijck M , Raschperger E , Andaloussi Mae M , Jung B , Lebouvier T , Ando K , Hofmann J , Keller A , Betsholtz C ( 2016 ) Analysis of the brain mural cell transcriptome . Sci Rep 6 : 35108 27725773 

    상세보기

43. Herdon HJ , Godfrey FM , Brown AM , Coulton S , Evans JR , Cairns WJ ( 2001 ) Pharmacological assessment of the role of the glycine transporter GlyT­1 in mediating high­affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes . Neuropharmacology 41 : 88 ？ 96 11445189 

    상세보기

44. Hering H , Sheng M ( 2001 ) Dendritic spines: structure, dynamics and regulation . Nat Rev Neurosci 2 : 880 ？ 888 11733795 

45. Hino S , Tanji C , Nakayama KI , Kikuchi A ( 2005 ) Phosphorylation of beta­catenin by cyclic AMP­dependent protein kinase stabilizes beta­catenin through inhibition of its ubiquitination . Mol Cell Biol 25 : 9063 ？ 9072 16199882 

46. Howitt J , Lackovic J , Low LH , Naguib A , Macintyre A , Goh CP , Callaway JK , Hammond V , Thomas T , Dixon M et al ( 2012 ) Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia . J Cell Biol 196 : 29 ？ 36 22213801 

    상세보기

47. Igarashi A , Itoh K , Yamada T , Adachi Y , Kato T , Murata D , Sesaki H , Iijima M ( 2018 ) Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility . J Biol Chem 293 : 9292 ？ 9300 29735527 

    상세보기

48. Javitt DC ( 2008 ) Glycine transport inhibitors and the treatment of schizophrenia . Biol Psychiat 63 : 6 ？ 8 18082555 

49. Jones CM , Smith M , Henderson MJ ( 2006 ) Reference data for cerebrospinal fluid and the utility of amino acid measurement for the diagnosis of inborn errors of metabolism . Ann Clin Biochem 43 : 63 ？ 66 16390611 

    상세보기

50. Jurado S , Benoist M , Lario A , Knafo S , Petrok CN , Esteban JA ( 2010 ) PTEN is recruited to the postsynaptic terminal for NMDA receptor­dependent long­term depression . EMBO J 29 : 2827 ？ 2840 20628354 

    상세보기

51. Kim JW , Kang KH , Burrola P , Mak TW , Lemke G ( 2008 ) Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium . Genes Dev 22 : 3147 ？ 3157 18997061 

    상세보기

52. Kim D , Pertea G , Trapnell C , Pimentel H , Kelley R , Salzberg SL ( 2013 ) TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions . Genome Biol 14 : R36 23618408 

    상세보기

53. Kiss H , Darai E , Kiss C , Kost­Alimova M , Klein G , Dumanski JP , Imreh S ( 2002 ) Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3 . Mamm Genome 13 : 646 ？ 655 12461651 

    상세보기

54. Knafo S , Sanchez­Puelles C , Palomer E , Delgado I , Draffin JE , Mingo J , Wahle T , Kaleka K , Mou L , Pereda­Perez I et al ( 2016 ) PTEN recruitment controls synaptic and cognitive function in Alzheimer's models . Nat Neurosci 19 : 443 ？ 453 26780512 

    상세보기

55. Knafo S , Esteban JA ( 2017 ) PTEN: local and global modulation of neuronal function in health and disease . Trends Neurosci 40 : 83 ？ 91 28081942 

    상세보기

56. Kowalczuk S , Broer A , Munzinger M , Tietze N , Klingel K , Broer S ( 2005 ) Molecular cloning of the mouse IMINO system: an Na+­ and Cl？dependent proline transporter . Biochem J 386 : 417 ？ 422 15689184 

    상세보기

57. Kurolap A , Armbruster A , Hershkovitz T , Hauf K , Mory A , Paperna T , Hannappel E , Tal G , Nijem Y , Sella E et al ( 2016 ) Loss of glycine transporter 1 causes a subtype of glycine encephalopathy with arthrogryposis and mildly elevated cerebrospinal fluid glycine . Am J Hum Genet 99 : 1172 ？ 1180 27773429 

    상세보기

58. Kuryatov A , Laube B , Betz H , Kuhse J ( 1994 ) Mutational analysis of the glycine­binding site of the NMDA receptor: structural similarity with bacterial amino acid­binding proteins . Neuron 12 : 1291 ？ 1300 8011339 

    상세보기

59. Kwon CH , Luikart BW , Powell CM , Zhou J , Matheny SA , Zhang W , Li Y , Baker SJ , Parada LF ( 2006 ) Pten regulates neuronal arborization and social interaction in mice . Neuron 50 : 377 ？ 388 16675393 

    상세보기

60. Lane HY , Huang CL , Wu PL , Liu YC , Chang YC , Lin PY , Chen PW , Tsai G ( 2006 ) Glycine transporter I inhibitor, N­methylglycine (sarcosine), added to clozapine for the treatment of schizophrenia . Biol Psychiat 60 : 645 ？ 649 16780811 

61. Larson J , Munkacsy E ( 2015 ) Theta­burst LTP . Brain Res 1621 : 38 ？ 50 25452022 

    상세보기

62. Lee HK , Kameyama K , Huganir RL , Bear MF ( 1998 ) NMDA induces long­term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampus . Neuron 21 : 1151 ？ 1162 9856470 

    상세보기

63. Lee HK , Barbarosie M , Kameyama K , Bear MF , Huganir RL ( 2000 ) Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity . Nature 405 : 955 ？ 959 10879537 

    상세보기

64. Lee EJ , Choi SY , Kim E ( 2015 ) NMDA receptor dysfunction in autism spectrum disorders . Curr Opin Pharmacol 20C : 8 ？ 13 

65. Liu QR , Lopez­Corcuera B , Mandiyan S , Nelson H , Nelson N ( 1993a ) Cloning and expression of a spinal cord­ and brain­specific glycine transporter with novel structural features . J Biol Chem 268 : 22802 ？ 22808 8226790 

    상세보기

66. Liu QR , Lopez­Corcuera B , Mandiyan S , Nelson H , Nelson N ( 1993b ) Molecular characterization of four pharmacologically distinct gamma­aminobutyric acid transporters in mouse brain [corrected] . J Biol Chem 268 : 2106 ？ 2112 8420981 

    상세보기

67. Long JM , LaPorte P , Paylor R , Wynshaw­Boris A ( 2004 ) Expanded characterization of the social interaction abnormalities in mice lacking Dvl1 . Genes Brain Behav 3 : 51 ？ 62 14960015 

    상세보기

68. Love MI , Huber W , Anders S ( 2014 ) Moderated estimation of fold change and dispersion for RNA­seq data with DESeq2 . Genome Biol 15 : 550 25516281 

    상세보기

69. Lugo JN , Smith GD , Morrison JB , White J ( 2013 ) Deletion of PTEN produces deficits in conditioned fear and increases fragile X mental retardation protein . Learn Mem 20 : 670 ？ 673 24241749 

70. Lugo JN , Smith GD , Arbuckle EP , White J , Holley AJ , Floruta CM , Ahmed N , Gomez MC , Okonkwo O ( 2014 ) Deletion of PTEN produces autism­like behavioral deficits and alterations in synaptic proteins . Front Mol Neurosci 7 : 27 24795561 

    상세보기

71. Malenka RC , Bear MF ( 2004 ) LTP and LTD: an embarrassment of riches . Neuron 44 : 5 ？ 21 15450156 

    상세보기

72. Maletic­Savatic M , Malinow R , Svoboda K ( 1999a ) Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity . Science 283 : 1923 ？ 1927 10082466 

    상세보기

73. Mammen AL , Kameyama K , Roche KW , Huganir RL ( 1997 ) Phosphorylation of the alpha­amino­3­hydroxy­5­methylisoxazole4­ propionic acid receptor GluR1 subunit by calcium/calmodulin­dependent kinase II . J Biol Chem 272 : 32528 ？ 32533 9405465 

74. Manahan­Vaughan D , Wildforster V , Thomsen C ( 2008 ) Rescue of hippocampal LTP and learning deficits in a rat model of psychosis by inhibition of glycine transporter­1 (GlyT1) . Eur J Neuorsci 28 : 1342 ？ 1350 

75. Martina M , Gorfinkel Y , Halman S , Lowe JA , Periyalwar P , Schmidt CJ , Bergeron R ( 2004 ) Glycine transporter type 1 blockade changes NMDA receptor­mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels . J Physiol 557 : 489 ？ 500 15064326 

76. McFarlane HG , Kusek GK , Yang M , Phoenix JL , Bolivar VJ , Crawley JN ( 2008 ) Autism­like behavioral phenotypes in BTBR T+tf/J mice . Genes Brain Behav 7 : 152 ？ 163 17559418 

    상세보기

77. Meng L , Ward AJ , Chun S , Bennett CF , Beaudet AL , Rigo F ( 2015 ) Towards a therapy for Angelman syndrome by targeting a long non­coding RNA . Nature 518 : 409 ？ 412 25470045 

78. Monyer H , Burnashev N , Laurie DJ , Sakmann B , Seeburg PH ( 1994 ) Developmental and regional expression in the rat brain and functional properties of four NMDA receptors . Neuron 12 : 529 ？ 540 7512349 

    상세보기

79. Mothet JP , Parent AT , Wolosker H , Brady Jr RO , Linden DJ , Ferris CD , Rogawski MA , Snyder SH ( 2000 ) D­serine is an endogenous ligand for the glycine site of the N­methyl­D­aspartate receptor . Proc Natl Acad Sci USA 97 : 4926 ？ 4931 10781100 

    상세보기

80. Nadler JJ , Moy SS , Dold G , Trang D , Simmons N , Perez A , Young NB , Barbaro RP , Piven J , Magnuson TR et al ( 2004 ) Automated apparatus for quantitation of social approach behaviors in mice . Genes Brain Behav 3 : 303 ？ 314 15344923 

    상세보기

81. Napoli E , Ross­Inta C , Wong S , Hung C , Fujisawa Y , Sakaguchi D , Angelastro J , Omanska­Klusek A , Schoenfeld R , Giulivi C ( 2012 ) Mitochondrial dysfunction in Pten haplo­insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53 . PLoS One 7 : e42504 22900024 

    상세보기

82. Nash SR , Giros B , Kingsmore SF , Kim KM , el­Mestikawy S , Dong Q , Fumagalli F , Seldin MF , Caron MG ( 1998 ) Cloning, gene structure and genomic localization of an orphan transporter from mouse kidney with six alternatively­spliced isoforms . Recept Channels 6 : 113 ？ 128 9932288 

    상세보기

83. Ohtsuki S ( 2004 ) New aspects of the blood­brain barrier transporters; its physiological roles in the central nervous system . Biol Pharm Bull 27 : 1489 ？ 1496 15467183 

    상세보기

84. Olney JW , Newcomer JW , Farber NB ( 1999 ) NMDA receptor hypofunction model of schizophrenia . J Psychiatr Res 33 : 523 ？ 533 10628529 

    상세보기

85. Papouin T , Ladepeche L , Ruel J , Sacchi S , Labasque M , Hanini M , Groc L , Pollegioni L , Mothet JP , Oliet SH ( 2012 ) Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists . Cell 150 : 633 ？ 646 22863013 

    상세보기

86. Papouin T , Oliet SH ( 2014 ) Organization, control and function of extrasynaptic NMDA receptors . Philos Trans R Soc Lond B Biol Sci 369 : 20130601 25225095 

87. Peineau S , Taghibiglou C , Bradley C , Wong TP , Liu L , Lu J , Lo E , Wu D , Saule E , Bouschet T et al ( 2007 ) LTP inhibits LTD in the hippocampus via regulation of GSK3beta . Neuron 53 : 703 ？ 717 17329210 

88. Planchon SM , Waite KA , Eng C ( 2008 ) The nuclear affairs of PTEN . J Cell Sci 121 : 249 ？ 253 18216329 

    상세보기

89. Protais P , Costentin J , Schwartz JC ( 1976 ) Climbing behavior induced by apomorphine in mice: a simple test for the study of dopamine receptors in striatum . Psychopharmacology 50 : 1 ？ 6 827755 

    상세보기

90. Purcell SM , Moran JL , Fromer M , Ruderfer D , Solovieff N , Roussos P , O'Dushlaine C , Chambert K , Bergen SE , Kahler A et al ( 2014 ) A polygenic burden of rare disruptive mutations in schizophrenia . Nature 506 : 185 ？ 190 24463508 

91. Qin L , Ma K , Wang ZJ , Hu Z , Matas E , Wei J , Yan Z ( 2018 ) Social deficits in Shank3­deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition . Nat Neurosci 21 : 564 ？ 575 29531362 

    상세보기

92. Riffee WH , Wilcox RE , Smith RV ( 1979 ) Stereotypic and hypothermic effects of apomorphine and N­n­propylnorapomorphine in mice . Eur J Pharmacol 54 : 273 ？ 277 570924 

    상세보기

93. Rinaldi C , Wood MJA ( 2018 ) Antisense oligonucleotides: the next frontier for treatment of neurological disorders . Nat Rev Neurol 14 : 9 ？ 21 29192260 

    상세보기

94. Roche KW , O'Brien RJ , Mammen AL , Bernhardt J , Huganir RL ( 1996 ) Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit . Neuron 16 : 1179 ？ 1188 8663994 

    상세보기

95. Saunders NR , Ek CJ , Habgood MD , Dziegielewska KM ( 2008 ) Barriers in the brain: a renaissance? Trends Neurosci 31 : 279 ？ 286 18471905 

    상세보기

96. Saunders NR , Daneman R , Dziegielewska KM , Liddelow SA ( 2013 ) Transporters of the blood­brain and blood­CSF interfaces in development and in the adult . Mol Aspects Med 34 : 742 ？ 752 23506907 

    상세보기

97. Schell MJ , Molliver ME , Snyder SH ( 1995 ) D­serine, an endogenous synaptic modulator: localization to astrocytes and glutamate­stimulated release . Proc Natl Acad Sci USA 92 : 3948 ？ 3952 7732010 

    상세보기

98. Scoles DR , Meera P , Schneider MD , Paul S , Dansithong W , Figueroa KP , Hung G , Rigo F , Bennett CF , Otis TS et al ( 2017 ) Antisense oligonucleotide therapy for spinocerebellar ataxia type 2 . Nature 544 : 362 ？ 366 28405024 

99. Sheng M , Sala C ( 2001 ) PDZ domains and the organization of supramolecular complexes . Annu Rev Neurosci 24 : 1 ？ 29 11283303 

    상세보기

100. Sheng M , Hoogenraad CC ( 2007 ) The postsynaptic architecture of excitatory synapses: a more quantitative view . Annu Rev Biochem 76 : 823 ？ 847 17243894 

     상세보기

101. Sheng M , Kim E ( 2011 ) The postsynaptic organization of synapses . Cold Spring Harbor Perspect Biol 3 : a005678 . 

102. Shi S , Hayashi Y , Esteban JA , Malinow R ( 2001 ) Subunit­specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons . Cell 105 : 331 ？ 343 11348590 

     상세보기

103. Silverman JL , Yang M , Lord C , Crawley JN ( 2010 ) Behavioural phenotyping assays for mouse models of autism . Nat Rev Neurosci 11 : 490 ？ 502 20559336 

     상세보기

104. Smith KE , Borden LA , Hartig PR , Branchek T , Weinshank RL ( 1992 ) Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors . Neuron 8 : 927 ？ 935 1534013 

     상세보기

105. Smith KE , Fried SG , Durkin MM , Gustafson EL , Borden LA , Branchek TA , Weinshank RL ( 1995 ) Molecular cloning of an orphan transporter. A new member of the neurotransmitter transporter family . FEBS Lett 357 : 86 ？ 92 8001687 

     상세보기

106. Spencer CI , Li N , Chen Q , Johnson J , Nevill T , Kammonen J , Ionescu­Zanetti C ( 2012 ) Ion channel pharmacology under flow: automation via well­plate microfluidics . Assay Drug Dev Technol 10 : 313 ？ 324 22574656 

     상세보기

107. Subramanian A , Tamayo P , Mootha VK , Mukherjee S , Ebert BL , Gillette MA , Paulovich A , Pomeroy SL , Golub TR , Lander ES et al ( 2005 ) Gene set enrichment analysis: a knowledge­based approach for interpreting genome­wide expression profiles . Proc Natl Acad Sci USA 102 : 15545 ？ 15550 16199517 

     상세보기

108. Suzuki A , Yamaguchi MT , Ohteki T , Sasaki T , Kaisho T , Kimura Y , Yoshida R , Wakeham A , Higuchi T , Fukumoto M et al ( 2001 ) T cell­specific loss of Pten leads to defects in central and peripheral tolerance . Immunity 14 : 523 ？ 534 11371355 

     상세보기

109. Tai CY , Mysore SP , Chiu C , Schuman EM ( 2007 ) Activity­regulated N­cadherin endocytosis . Neuron 54 : 771 ？ 785 17553425 

     상세보기

110. Takahashi Y , Morales FC , Kreimann EL , Georgescu MM ( 2006 ) PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling . EMBO J 25 : 910 ？ 920 16456542 

     상세보기

111. Takanaga H , Tokuda N , Ohtsuki S , Hosoya K , Terasaki T ( 2002 ) ATA2 is predominantly expressed as system A at the blood­brain barrier and acts as brain­to­blood efflux transport for L­proline . Mol Pharmacol 61 : 1289 ？ 1296 12021389 

     상세보기

112. Takanaga H , Mackenzie B , Suzuki Y , Hediger MA ( 2005 ) Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino . J Biol Chem 280 : 8974 ？ 8984 15632147 

     상세보기

113. Takeuchi K , Gertner MJ , Zhou J , Parada LF , Bennett MV , Zukin RS ( 2013 ) Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism . Proc Natl Acad Sci USA 110 : 4738 ？ 4743 23487788 

     상세보기

114. Taurin S , Sandbo N , Qin Y , Browning D , Dulin NO ( 2006 ) Phosphorylation of beta­catenin by cyclic AMP­dependent protein kinase . J Biol Chem 281 : 9971 ？ 9976 16476742 

115. Tilot AK , Bebek G , Niazi F , Altemus JB , Romigh T , Frazier TW , Eng C ( 2016 ) Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder . Mol Psychiatry 21 : 118 ？ 125 25754085 

     상세보기

116. Tolkacheva T , Boddapati M , Sanfiz A , Tsuchida K , Kimmelman AC , Chan AM ( 2001 ) Regulation of PTEN binding to MAGI­2 by two putative phosphorylation sites at threonine 382 and 383 . Can Res 61 : 4985 ？ 4989 

117. Tsai G , Lane HY , Yang P , Chong MY , Lange N ( 2004a ) Glycine transporter I inhibitor, N­methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia . Biol Psychiatry 55 : 452 ？ 456 15023571 

     상세보기

118. Tsai G , Ralph­Williams RJ , Martina M , Bergeron R , Berger­Sweeney J , Dunham KS , Jiang Z , Caine SB , Coyle JT ( 2004b ) Gene knockout of glycine transporter 1: characterization of the behavioral phenotype . Proc Natl Acad Sci USA 101 : 8485 ？ 8490 15159536 

     상세보기

119. Vaidyanathan S , Orr BG , Banaszak Holl MM ( 2014 ) Detergent induction of HEK 293A cell membrane permeability measured under quiescent and superfusion conditions using whole cell patch clamp . J Phys Chem B 118 : 2112 ？ 2123 24548291 

120. Vanlandewijck M , He L , Mae MA , Andrae J , Ando K , Del Gaudio F , Nahar K , Lebouvier T , Lavina B , Gouveia L et al ( 2018 ) A molecular atlas of cell types and zonation in the brain vasculature . Nature 554 : 475 ？ 480 29443965 

121. Vazquez F , Ramaswamy S , Nakamura N , Sellers WR ( 2000 ) Phosphorylation of the PTEN tail regulates protein stability and function . Mol Cell Biol 20 : 5010 ？ 5018 10866658 

     상세보기

122. Verleysdonk S , Martin H , Willker W , Leibfritz D , Hamprecht B ( 1999 ) Rapid uptake and degradation of glycine by astroglial cells in culture: synthesis and release of serine and lactate . Glia 27 : 239 ？ 248 10457370 

     상세보기

123. Vicini S , Wang JF , Li JH , Zhu WJ , Wang YH , Luo JH , Wolfe BB , Grayson DR ( 1998 ) Functional and pharmacological differences between recombinant N­methyl­D­aspartate receptors . J Neurophysiol 79 : 555 ？ 566 9463421 

124. Wilcox RE , Riffee WH , Smith RV ( 1979 ) Pharmacological basis for N­n­propylnorapomorphine induced stereotypic cage climbing and behavioral arousal in mice . Pharmacol Biochem Behav 11 : 653 ？ 659 43980 

125. Williams MR , DeSpenza Jr T , Li M , Gulledge AT , Luikart BW ( 2015 ) Hyperactivity of newborn Pten knock­out neurons results from increased excitatory synaptic drive . J Neurosci 35 : 943 ？ 959 25609613 

     상세보기

126. Won H , Lee HR , Gee HY , Mah W , Kim JI , Lee J , Ha S , Chung C , Jung ES , Cho YS et al ( 2012 ) Autistic­like social behaviour in Shank2­mutant mice improved by restoring NMDA receptor function . Nature 486 : 261 ？ 265 22699620 

     상세보기

127. Wu X , Hepner K , Castelino­Prabhu S , Do D , Kaye MB , Yuan XJ , Wood J , Ross C , Sawyers CL , Whang YE ( 2000 ) Evidence for regulation of the PTEN tumor suppressor by a membrane­localized multi­PDZ domain containing scaffold protein MAGI­2 . Proc Natl Acad Sci USA 97 : 4233 ？ 4238 10760291 

     상세보기

128. Yu X , Malenka RC ( 2003 ) Beta­catenin is critical for dendritic morphogenesis . Nat Neurosci 6 : 1169 ？ 1177 14528308 

129. Yuan NY , Poe MM , Witzigmann C , Cook JM , Stafford D , Arnold LA ( 2016 ) Characterization of GABAA receptor ligands with automated patch­clamp using human neurons derived from pluripotent stem cells . J Pharmacol Toxicol Methods 82 : 109 ？ 114 27544543 

     상세보기

130. Zhan Y , Paolicelli RC , Sforazzini F , Weinhard L , Bolasco G , Pagani F , Vyssotski AL , Bifone A , Gozzi A , Ragozzino D et al ( 2014 ) Deficient neuron­microglia signaling results in impaired functional brain connectivity and social behavior . Nat Neurosci 17 : 400 ？ 406 24487234 

     상세보기

131. Zhang S , Taghibiglou C , Girling K , Dong Z , Lin SZ , Lee W , Shyu WC , Wang YT ( 2013 ) Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries . J Neurosci 33 : 7997 ？ 8008 23637190 

     상세보기

활용도 Top5 논문

더보기

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.