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[해외논문] Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted therapy through Src kinase activation 원문보기

Cell death and differentiation, v.28 no.3, 2021년, pp.968 - 984  

Lee, Sang-Hyun (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea) ,  Kim, Jin-Man (Department of Pathology, Cancer Research Institute and Infection Control Convergence Research Center, Chungnam National University College of Medicine, 266 Munhwa-ro, Jung-gu, Daejeon, 35015 Republic of Korea) ,  Lee, Dong Gwang (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea) ,  Lee, Jangwook (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea) ,  Park, Jong-Gil (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea) ,  Han, Tae-Su (Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and) ,  Cho, Hyun-Soo ,  Cho, Young-Lai ,  Bae, Kwang-Hee ,  Park, Young-Jun ,  Lee, Seon-Jin ,  Lee, Moo-Seung ,  Huh, Yong-Min ,  Jo, Deog Yeon ,  Yun, Hwan-Jung ,  Jeon, Heung Jin ,  Kim, Nayoung ,  Joo, Mina ,  Kim, Jang-Seong ,  Lee, Hyo Jin ,  Min, Jeong-Ki

Abstract AI-Helper 아이콘AI-Helper

Gallbladder carcinoma (GBC) exhibits poor prognosis due to local recurrence, metastasis, and resistance to targeted therapies. Using clinicopathological analyses of GBC patients along with molecular in vitro and tumor in vivo analysis of GBC cells, we showed that reduction of Dsg2 expression was hig...

참고문헌 (45)

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