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[해외논문] Extracellular vesicles derived from macrophages display glycyl‐tRNA synthetase 1 and exhibit anti‐cancer activity 원문보기

Journal of extracellular vesicles, v.10 no.1, 2020년, pp.e12029 -   

Goughnour, Peter C. (Institute for Artificial Intelligence and Biomedical Research Medicinal Bioconvergence Research Center College of Pharmacy & College of Medicine Gangnam Severance Hospital Yonsei University Incheon Korea) ,  Park, Min Chul (Institute for Artificial Intelligence and Biomedical Research Medicinal Bioconvergence Research Center College of Pharmacy & College of Medicine Gangnam Severance Hospital Yonsei University Incheon Korea) ,  Kim, Sang Bum (Institute for Artificial Intelligence and Biomedical Research Medicinal Bioconvergence Research Center College of Pharmacy & College of Medicine Gangnam Severance Hospital Yonsei University Incheon Korea) ,  Jun, Sangmi (Division of Electron Microscopic Research Korea Basic Science Institute Daejeon Korea) ,  Yang, Won Suk (Institute for Artificial Intelligence and Biomedical Research Medicinal Bioconvergence Research Center College of Pharmacy & College of Medicine Gangnam Severance Hospital Yonsei University) ,  Chae, Sehyun ,  Cho, Seongmin ,  Song, Chihong ,  Lee, Ji‐Hyun ,  Hyun, Jae Kyung ,  Kim, Byung Gyu ,  Hwang, Daehee ,  Jung, Hyun Suk ,  Gho, Yong Song ,  Kim, Sunghoon

Abstract AI-Helper 아이콘AI-Helper

AbstractGlycyl‐tRNA synthetase 1 (GARS1), a cytosolic enzyme secreted from macrophages, promotes apoptosis in cancer cells. However, the mechanism underlying GARS1 secretion has not been elucidated. Here, we report that GARS1 is secreted through unique extracellular vesicles (EVs) with a hydr...

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