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[해외논문] Switching Chemoselectivity Based on the Ring Size: How to Make Ring-Fused Indoles Using Transition-Metal-Mediated Cross-Coupling

ACS catalysis, v.11, 2021년, pp.12821 - 12832  

Kim, Jang-Yeop (Department of Chemistry , Hanyang University , 222 Wangsimni-ro , Seongdong-gu, Seoul 04763 , Republic of Korea) ,  Lee, Woojong (Department of Chemistry , Korea Advanced Institute of Science and Technology (KAIST) , Daejeon 34141 , Republic of Korea) ,  Kang, Hyung-Joon (Department of Chemistry , Hanyang University , 222 Wangsimni-ro , Seongdong-gu, Seoul 04763 , Republic of Korea) ,  Jeon, Tae-Hong (Department of Chemistry , Hanyang University , 222 Wangsimni-ro , Seongdong-gu, Seoul 04763 , Republic of Korea) ,  Baik, Mu-Hyun ,  Cho, Cheon-Gyu

Abstract AI-Helper 아이콘AI-Helper

Pyrroloazocine indole alkaloids consisting of eight-membered azacycle fused to pyrrole and indole units exhibit intriguing pharmacological functions but still pose a synthetic challenge. Here, we report an alternative synthetic strategy for the pyrroloazocine indole core from two key steps: (i) regi...

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