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Enhanced In Vitro and In Vivo Efficacy of Alginate/Silk Protein/Hyaluronic Acid with Polypeptide Microsphere Delivery for Tissue Regeneration of Articular Cartilage

Journal of biomedical nanotechnology, v.17 no.5, 2021년, pp.901 - 909  

Han, Long (Department of Orthopedics, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou 213003, China) ,  Xu, Nanwei (Department of Orthopedics, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou 213003, China) ,  Lv, Songwei (School of Pharmacy, Changzhou University, Changzhou 213164, China) ,  Yin, Jianjian (Department of Orthopedics, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou 213003, China) ,  Zheng, Dong (Department of Orthopedics, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou 213003, China) ,  Li, Xin (School of Pharmacy, Changzhou University, Changzhou 213164, China)

Abstract AI-Helper 아이콘AI-Helper

Alginate/Silk fibroin/hyaluronic acid (ALG/SF/HA) nanocomposites were synthesised using blending, inter-linking, and lyophilization methods. We investigated the physicochemical properties of the resulting nanocomposites, including their water retention, weight loss, porosity and cytocompatibility. T...

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