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[해외논문] AC-motif: a DNA motif containing adenine and cytosine repeat plays a role in gene regulation 원문보기

Nucleic acids research, v.49 no.17, 2021년, pp.10150 - 10165  

Hur, Jeong Hwan (Department of Precision Medicine, Graduate Schoold of Basic Medical Science (GSBMS), Institute for Anti-microbial Resistance Research and Therapeutics, Sungkyunkwan University School of Medicine , Suwon 16419, Republic of Korea) ,  Kang, Chan Young (Department of Chemistry, Hanyang University , Seoul 04763, Republic of Korea) ,  Lee, Sungjin (Department of Chemistry, Gwangju Institute of Science and Technology , Gwangju 61005, Republic of Korea) ,  Parveen, Nazia (Department of Precision Medicine, Graduate Schoold of Basic Medical Science (GSBMS), Institute for Anti-microbial Resistance Research and Therapeutics, Sungkyunkwan University School of Medicine , Suwon 16419, Republic of Korea) ,  Yu, Jihyeon (Department of Chemistry, Hanyang University , Seoul 04763, Republic of Korea) ,  Shamim, Amen (Department of Precision Medicine, Graduate Schoold of Basic Medical Science (GSBMS), I) ,  Yoo, Wanki ,  Ghosh, Ambarnil ,  Bae, Sangsu ,  Park, Chin-Ju ,  Kim, Kyeong Kyu

Abstract AI-Helper 아이콘AI-Helper

AbstractI-motif or C4 is a four-stranded DNA structure with a protonated cytosine:cytosine base pair (C+:C) found in cytosine-rich sequences. We have found that oligodeoxynucleotides containing adenine and cytosine repeats form a stable secondary structure at a physiological pH with magnesium ion, w...

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