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[해외논문] MMP9-Sensitive PEG-Shedding Nanoliposomes for Targeted Codelivery of Erlotinib and Doxorubicin to MDA-MB-231 Cells

Acs applied polymer materials, v.3 no.11, 2021년, pp.5982 - 5998  

Kim, So-Yeon (Therapeutics & Biotechnology Division , Korea Research Institute of Chemical Technology , Daejeon 34114 , Republic of Korea) ,  Yoon, Ji Young (Bioconvergence Analysis , Korea Basic Science Institute , Cheongju-si 28119 , Republic of Korea) ,  Lee, Haesoo (College of Pharmacy , Chungnam National University , Daejeon 34134 , Republic of Korea) ,  Cho, Cheong-Weon (College of Pharmacy , Chungnam National University , Daejeon 34134 , Republic of Korea) ,  Seong, Hasoo

Abstract AI-Helper 아이콘AI-Helper

Tumor microenvironment-sensitive nanoliposomes (TMS-NLs) were prepared as triple negative breast cancer (TNBC)-specific carriers for synergistic therapeutics. The NLs shed polyethylene glycol (PEG) by matrix metalloproteinase 9 (MMP9) secreted from the cancer cells, expose a cell-penetrating peptide...

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참고문헌 (47)

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