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[해외논문] Modeling Hypoxic Stress In Vitro Using Human Embryonic Stem Cells Derived Cardiomyocytes Matured by FGF4 and Ascorbic Acid Treatment 원문보기

Cells, v.10 no.10, 2021년, pp.2741 -   

Choi, Seung-Cheol (Department of Cardiology, Cardiovascular Center, Korea University College of Medicine, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea) ,  Seo, Ha-Rim (Department of Cardiology, Cardiovascular Center, Korea University College of Medicine, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea) ,  Cui, Long-Hui (Department of Cardiology, Cardiovascular Center, Korea University College of Medicine, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea) ,  Song, Myeong-Hwa (Department of Cardiology, Cardiovascular Center, Korea University College of Medicine, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea) ,  Noh, Ji-Min (Department of Cardiology, Cardiovascular Center, Korea University College of Medicine, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea) ,  Kim, Kyung-Seob (Department of Cardiology, Cardiovascular Center, Korea University College of Medicine, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea) ,  Choi, Ji-Hyun (Department of Cardiology, Cardiovascular Center, Korea University College of Medicine, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea) ,  Kim, Jong-Ho (Department of Cardiology, Cardiovascular Center, Korea Univers) ,  Park, Chi-Yeon ,  Joo, Hyung Joon ,  Hong, Soon Jun ,  Ko, Tae Hee ,  Choi, Jong-Il ,  Kim, Hyo Jin ,  Kim, Jong-Hoon ,  Paek, Se-Hwan ,  Park, Ji-Na ,  Kim, Dong-Hyung ,  Jang, Yongjun ,  Park, Yongdoo ,  Lim, Do-Sun

Abstract ▼ AI-Helper 아이콘AI-Helper

Mature cardiomyocytes (CMs) obtained from human pluripotent stem cells (hPSCs) have been required for more accurate in vitro modeling of adult-onset cardiac disease and drug discovery. Here, we found that FGF4 and ascorbic acid (AA) induce differentiation of BG01 human embryonic stem cell-cardiogeni...

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