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NTIS 바로가기eLife, v.10, 2021년, pp.e70079 -
Lim, Soyeon (Department of Biological Sciences, Korea Advanced Institute of Science and Technology Daejeon Republic of Korea) , Kim, You-Joung (Department of Biological Sciences, Korea Advanced Institute of Science and Technology Daejeon Republic of Korea) , Park, Sooyeon (Department of Biological Sciences, Korea Advanced Institute of Science and Technology Daejeon Republic of Korea) , Choi, Ji-heon (Department of Biological Sciences, Korea Advanced Institute of Science and Technology Daejeon Republic of Korea) , Sung, Young Hoon (Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University Yonsei Republic of Korea) , Nishimori, Katsuhiko (Department of Obesity and Internal Inflammation) , Kozmik, Zbynek (Bioregulation and Pharmacological Medicine, Fukushima Medical University Fukushima Japan) , Lee, Han-Woong (Institute of Molecular Genetics of the Czech Academy of Sciences Prague) , Kim, Jin Woo
Retinal progenitor cells (RPCs) divide in limited numbers to generate the cells comprising vertebrate retina. The molecular mechanism that leads RPC to the division limit, however, remains elusive. Here, we find that the hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) in an RPC...
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