$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[해외논문] Investigation on the Effect of Cyclic Stretch and Hypoxia on Recovery of Damaged Skeletal Muscle Cells Using Microfluidic System

Advanced materials technologies, v.6 no.11, 2021년, pp.2100465 -   

Kim, Jaesang (Department of Mechanical Engineering Korea Advanced Institute of Science and Technology Daejeon Republic of Korea) ,  Kim, Wanho (Department of Mechanical Engineering Korea Advanced Institute of Science and Technology Daejeon Republic of Korea) ,  Ahn, Jisong (Research Group of Natural Materials and Metabolism Korea Food Research Institute Wanju‐) ,  Jang, Young Jin (gun Republic of Korea) ,  Park, Hyung‐Soon (Research Group of Natural Materials and Metabolism Korea Food Research Institute Wanju‐) ,  Jeon, Jessie S. (gun Republic of Korea)

Abstract AI-Helper 아이콘AI-Helper

AbstractTo develop an effective treatment for muscle recovery, costimuli effect of cyclic stretch and hypoxia on the recovery of oxidative damaged skeletal muscle cells is investigated. C2C12 myoblast cells are differentiated into myotube in culture dish followed by seeding the myotubes in the micro...

참고문헌 (82)

  1. G. V. R. Inc. Weight Management Market Size Share & Trends Analysis Report By Diet (Meals Beverages Supplements) By Equipment (Fitness Equipment Surgical Equipment) By Services By Region And Segment Forecasts 2018-2025 https://www.grandviewresearch.com/industry-analysis/weight-management-market accessed: June 2021. 

  2. G. V. R. Inc. Protein Supplements Market Size Share & Trends Analysis Report By Product (Powder Ready to Drink) By Application By Raw Material By Source By Distribution Channel By Region And Segment Forecasts 2019-2028 https://www.grandviewresearch.com/industry-analysis/protein-supplements-market accessed: June 2021. 

  3. J. Orthop. Rehabil. Kachanathu S. J. 2 1 2015 

  4. Trends Sport Sci. Contrò V. 23 2016 

  5. Gao Smith, Tianqi Tenchi, Gallagher, Sean. Impact of loading and work rest intervals on muscle micro-trauma. International journal of industrial ergonomics, vol.66, 161-168.

  6. Close, Graeme L., Ashton, Tony, McArdle, Anne, MacLaren, Don P.M.. The emerging role of free radicals in delayed onset muscle soreness and contraction-induced muscle injury. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, vol.142, no.3, 257-266.

  7. Hotfiel, Thilo, Freiwald, Jürgen, Hoppe, Matthias, Lutter, Christoph, Forst, Raimund, Grim, Casper, Bloch, Wilhelm, Hüttel, Moritz, Heiss, Rafael. Advances in Delayed-Onset Muscle Soreness (DOMS): Part I: Pathogenesis and Diagnostics. Sportverletzung Sportschaden : Organ der Gesellschaft für Orthopädisch-Traumatologische Sportmedizin, vol.32, no.4, 243-250.

  8. Owens, Daniel J., Twist, Craig, Cobley, James N., Howatson, Glyn, Close, Graeme L.. Exercise‐induced muscle damage: What is it, what causes it and what are the nutritional solutions?. European journal of sport science, vol.19, no.1, 71-85.

  9. Ismail, Hesham M., Scapozza, Leonardo, Ruegg, Urs T., Dorchies, Olivier M.. Diapocynin, a Dimer of the NADPH Oxidase Inhibitor Apocynin, Reduces ROS Production and Prevents Force Loss in Eccentrically Contracting Dystrophic Muscle. PloS one, vol.9, no.10, e110708-.

  10. Steinbacher, Peter, Eckl, Peter. Impact of Oxidative Stress on Exercising Skeletal Muscle. Biomolecules, vol.5, no.2, 356-377.

  11. He, Feng, Li, Juan, Liu, Zewen, Chuang, Chia-Chen, Yang, Wenge, Zuo, Li. Redox Mechanism of Reactive Oxygen Species in Exercise. Frontiers in physiology, vol.7, 486-.

  12. Xiao, Yajuan, Karam, Chehade, Yi, Jianxun, Zhang, Lin, Li, Xuejun, Yoon, Dosuk, Wang, Huan, Dhakal, Kamal, Ramlow, Paul, Yu, Tian, Mo, Zhaohui, Ma, Jianjie, Zhou, Jingsong. ROS-related mitochondrial dysfunction in skeletal muscle of an ALS mouse model during the disease progression. Pharmacological research : the official journal of the Italian Pharmacological Society, vol.138, 25-36.

  13. Longo, Victor, Jacobson, Jon A., Fessell, David P., Mautner, Kenneth. Ultrasound Findings of Delayed‐Onset Muscle Soreness. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, vol.35, no.11, 2517-2521.

  14. Agten, Christoph A., Buck, Florian M., Dyer, Linda, Flück, Martin, Pfirrmann, Christian W. A., Rosskopf, Andrea B.. Delayed-Onset Muscle Soreness: Temporal Assessment With Quantitative MRI and Shear-Wave Ultrasound Elastography. AJR : American journal of roentgenology, vol.208, no.2, 402-412.

  15. Chaillou, Thomas, Lanner, Johanna T.. Regulation of myogenesis and skeletal muscle regeneration: effects of oxygen levels on satellite cell activity. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol.30, no.12, 3929-3941.

  16. Rizo-Roca, D., Ríos-Kristjíánsson, J. G., Níáúíáúñez-Espinosa, C., Santos-Alves, E., Goncalves, I. O., Magalhíáúñães, J., Ascensíáúñãão, A., Pagíáúñããès, T., Viscor, G., Torrella, J. R.. Intermittent hypobaric hypoxia combined with aerobic exercise improves muscle morphofunctional recovery after eccentric exercise to exhaustion in trained rats. Journal of applied physiology, vol.122, no.3, 580-592.

  17. B.Schneider University of Nevada Las Vegas Las Vegas United States 2018. 

  18. High Altitude Medicine & Biology Ross C. I. 2019 

  19. Tiidus, Peter M.. Alternative treatments for muscle injury: massage, cryotherapy, and hyperbaric oxygen. Current reviews in musculoskeletal medicine, vol.8, no.2, 162-167.

  20. Cochrane Database Syst. Rev. Herbert R. CD004577 7 2011 

  21. Mayfield, D., Farris, D., Cresswell, A., Lichtwark, G.. Effect of muscle force during stretch on eccentric contraction-induced muscle damage. Journal of science and medicine in sport, vol.20, no.suppl3, 56-56.

  22. Chen, Xiaoxiao, Du, Wenqiang, Cai, Ze, Ji, Shengyun, Dwivedi, Monika, Chen, Jianfeng, Zhao, Gang, Chu, Jiaru. Uniaxial Stretching of Cell-Laden Microfibers for Promoting C2C12 Myoblasts Alignment and Myofibers Formation. ACS applied materials & interfaces, vol.12, no.2, 2162-2170.

  23. Park, Hyoungshin, Bhalla, Rajat, Saigal, Rajiv, Radisic, Milica, Watson, Nicki, Langer, Robert, Vunjak-Novakovic, Gordana. Effects of electrical stimulation in C2C12 muscle constructs. Journal of tissue engineering and regenerative medicine, vol.2, no.5, 279-287.

  24. Thomaz, Sergio Ricardo, Cipriano Jr, Gerson, Formiga, Magno Ferreira, Fachin-Martins, Emerson, Cipriano, Graziella França Bernardelli, Martins, Wagner Rodrigues, Cahalin, Lawrence Patrick. Effect of electrical stimulation on muscle atrophy and spasticity in patients with spinal cord injury - a systematic review with meta-analysis. Spinal cord : the official journal of the International Medical Society of Paraplegia, vol.57, no.4, 258-266.

  25. Yamada, Takashi, Himori, Koichi, Tatebayashi, Daisuke, Yamada, Ryotaro, Ashida, Yuki, Imai, Tomihiro, Akatsuka, Masayuki, Masuda, Yoshiki, Kanzaki, Keita, Watanabe, Daiki, Wada, Masanobu, Westerblad, Håkan, Lanner, Johanna T.. Electrical Stimulation Prevents Preferential Skeletal Muscle Myosin Loss in Steroid-Denervation Rats. Frontiers in physiology, vol.9, 1111-.

  26. Naskar, Sharmistha, Kumaran, V., Basu, Bikramjit. On The Origin of Shear Stress Induced Myogenesis Using PMMA Based Lab-on-Chip. ACS biomaterials science & engineering, vol.3, no.6, 1154-1171.

  27. Juffer, Petra, Bakker, Astrid D., Klein-Nulend, Jenneke, Jaspers, Richard T.. Mechanical Loading by Fluid Shear Stress of Myotube Glycocalyx Stimulates Growth Factor Expression and Nitric Oxide Production. Cell biochemistry and biophysics, vol.69, no.3, 411-419.

  28. Xie, Liwei, Yin, Amelia, Nichenko, Anna S., Beedle, Aaron M., Call, Jarrod A., Yin, Hang. Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration. The Journal of clinical investigation, vol.128, no.6, 2339-2355.

  29. Kozakowska, Magdalena, Pietraszek-Gremplewicz, Katarzyna, Jozkowicz, Alicja, Dulak, Jozef. The role of oxidative stress in skeletal muscle injury and regeneration: focus on antioxidant enzymes. Journal of muscle research and cell motility, vol.36, no.6, 377-393.

  30. Lee, Moon Hee, Han, Min Ho, Lee, Dae-Sung, Park, Cheol, Hong, Su-Hyun, Kim, Gi-Young, Hong, Sang Hoon, Song, Kyoung Seob, Choi, Il-Whan, Cha, Hee-Jae, Choi, Yung Hyun. Morin exerts cytoprotective effects against oxidative stress in C2C12 myoblasts via the upregulation of Nrf2-dependent HO-1 expression and the activation of the ERK pathway. International journal of molecular medicine, vol.39, no.2, 399-406.

  31. McDonagh, Ellen M., Thorn, Caroline F., Callaghan, John T., Altman, Russ B., Klein, Teri E.. PharmGKB summary: uric acid-lowering drugs pathway, pharmacodynamics. Pharmacogenetics and genomics, vol.24, no.9, 464-476.

  32. Apel, Klaus, Hirt, Heribert. REACTIVE OXYGEN SPECIES: Metabolism, Oxidative Stress, and Signal Transduction. Annual review of plant biology, vol.55, 373-399.

  33. Wardman, P.. Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: Progress, pitfalls, and prospects. Free radical biology & medicine, vol.43, no.7, 995-1022.

  34. McDonagh, Ellen M., Bautista, José M., Youngster, Ilan, Altman, Russ B., Klein, Teri E.. PharmGKB summary: methylene blue pathway. Pharmacogenetics and genomics, vol.23, no.9, 498-508.

  35. Wu, Fan, Tian, Fuju, Zeng, Weihong, Liu, Xiaorui, Fan, Jianxia, Lin, Yi, Zhang, Yan. Role of peroxiredoxin2 downregulation in recurrent miscarriage through regulation of trophoblast proliferation and apoptosis. Cell death & disease, vol.8, no.6, e2908-.

  36. Tang, Jiayong, He, Aihua, Yan, Hui, Jia, Gang, Liu, Guangmang, Chen, Xiaoling, Cai, Jingyi, Tian, Gang, Shang, Haiying, Zhao, Hua. Damage to the myogenic differentiation of C2C12 cells by heat stress is associated with up-regulation of several selenoproteins. Scientific reports, vol.8, 10601-.

  37. Shin, Yoojin, Han, Sewoon, Jeon, Jessie S, Yamamoto, Kyoko, Zervantonakis, Ioannis K, Sudo, Ryo, Kamm, Roger D, Chung, Seok. Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels. Nature protocols, vol.7, no.7, 1247-1259.

  38. Sung, Jong Hwan, Koo, Jamin, Shuler, Michael L.. Mimicking the Human Physiology with Microphysiological Systems (MPS). Biochip journal, vol.13, no.2, 115-126.

  39. Liu, Wenwen, Song, Jing, Du, Xiaohui, Zhou, Yang, Li, Yang, Li, Rui, Lyu, Li, He, Yeting, Hao, Junxia, Ben, Jing, Wang, Wei, Shi, Haibin, Wang, Qi. AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model. Acta Biomaterialia: structure-property-function relationships in biomaterials, vol.91, 195-208.

  40. Nam, Hyeono, Funamoto, Kenichi, Jeon, Jessie S.. Cancer cell migration and cancer drug screening in oxygen tension gradient chip. Biomicrofluidics, vol.14, no.4, 044107-.

  41. Nam, Ungsig, Kim, Seunggyu, Park, Joonha, Jeon, Jessie S.. Lipopolysaccharide-Induced Vascular Inflammation Model on Microfluidic Chip. Micromachines, vol.11, no.8, 747-.

  42. Shimizu, K., Araki, H., Sakata, K., Tonomura, W., Hashida, M., Konishi, S.. Microfluidic devices for construction of contractile skeletal muscle microtissues. Journal of bioscience and bioengineering, vol.119, no.2, 212-216.

  43. Occhetta, Paola, Mainardi, Andrea, Votta, Emiliano, Vallmajo-Martin, Queralt, Ehrbar, Martin, Martin, Ivan, Barbero, Andrea, Rasponi, Marco. Hyperphysiological compression of articular cartilage induces an osteoarthritic phenotype in a cartilage-on-a-chip model. Nature biomedical engineering, vol.3, no.7, 545-557.

  44. Kolanowski, Tomasz Jan, Busek, Mathias, Schubert, Mario, Dmitrieva, Anna, Binnewerg, Björn, Pöche, Jessie, Fisher, Konstanze, Schmieder, Florian, Grünzner, Stefan, Hansen, Sinah, Richter, Andreas, El-Armouche, Ali, Sonntag, Frank, Guan, Kaomei. Enhanced structural maturation of human induced pluripotent stem cell-derived cardiomyocytes under a controlled microenvironment in a microfluidic system. Acta Biomaterialia: structure-property-function relationships in biomaterials, vol.102, 273-286.

  45. Agrawal, Gaurav, Aung, Aereas, Varghese, Shyni. Skeletal muscle-on-a-chip: an in vitro model to evaluate tissue formation and injury. Lab on a chip, vol.17, no.20, 3447-3461.

  46. Ortega, María A., Fernández-Garibay, Xiomara, Castaño, Albert G., De Chiara, Francesco, Hernández-Albors, Alejandro, Balaguer-Trias, Jordina, Ramón-Azcón, Javier. Muscle-on-a-chip with an on-site multiplexed biosensing system for in situ monitoring of secreted IL-6 and TNF-α. Lab on a chip, vol.19, no.15, 2568-2580.

  47. Zahavi, Eitan Erez, Ionescu, Ariel, Gluska, Shani, Gradus, Tal, Ben-Yaakov, Keren, Perlson, Eran. A compartmentalized microfluidic neuromuscular co-culture system reveals spatial aspects of GDNF functions. Journal of cell science, vol.128, no.6, 1241-1252.

  48. Uzel, Sebastien G. M., Platt, Randall J., Subramanian, Vidya, Pearl, Taylor M., Rowlands, Christopher J., Chan, Vincent, Boyer, Laurie A., So, Peter T. C., Kamm, Roger D.. Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units. Science advances, vol.2, no.8, e1501429-.

  49. Osaki, Tatsuya, Uzel, Sebastien G. M., Kamm, Roger D.. On-chip 3D neuromuscular model for drug screening and precision medicine in neuromuscular disease. Nature protocols, vol.15, no.2, 421-449.

  50. Osaki, Tatsuya, Uzel, Sebastien G. M., Kamm, Roger D.. Microphysiological 3D model of amyotrophic lateral sclerosis (ALS) from human iPS-derived muscle cells and optogenetic motor neurons. Science advances, vol.4, no.10, eaat5847-.

  51. Kim, Wanho, Kim, Jaesang, Park, Hyung-Soon, Jeon, Jessie S.. Development of Microfluidic Stretch System for Studying Recovery of Damaged Skeletal Muscle Cells. Micromachines, vol.9, no.12, 671-.

  52. Fan, Xiying, Hussien, Rajaa, Brooks, George A.. H2O2-induced mitochondrial fragmentation in C2C12 myocytes. Free radical biology & medicine, vol.49, no.11, 1646-1654.

  53. Bansai, Shinako, Morikura, Takashi, Onoe, Hiroaki, Miyata, Shogo. Effect of Cyclic Stretch on Tissue Maturation in Myoblast-Laden Hydrogel Fibers. Micromachines, vol.10, no.6, 399-.

  54. Agley, Chibeza C., Velloso, Cristiana P., Lazarus, Norman R., Harridge, Stephen D. R.. An Image Analysis Method for the Precise Selection and Quantitation of Fluorescently Labeled Cellular Constituents : Application to the Measurement of Human Muscle Cells in Culture. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, vol.60, no.6, 428-438.

  55. Kitzmann, Magali, Carnac, Gilles, Vandromme, Marie, Primig, Michael, Lamb, Ned J.C., Fernandez, Anne. The Muscle Regulatory Factors MyoD and Myf-5 Undergo Distinct Cell Cycle–specific Expression in Muscle Cells. The Journal of cell biology, vol.142, no.6, 1447-1459.

  56. Schöneich, Christian, Dremina, Elena, Galeva, Nadezhda, Sharov, Victor. Apoptosis in differentiating C2C12 muscle cells selectively targets Bcl-2-deficient myotubes. Apoptosis : an international journal on programmed cell death, vol.19, no.1, 42-57.

  57. Denes, Lance T., Riley, Lance A., Mijares, Joseph R., Arboleda, Juan D., McKee, Kendra, Esser, Karyn A., Wang, Eric T.. Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation. Skeletal muscle, vol.9, 17-.

  58. 10.1016/bs.mie.2015.09.026 

  59. Sun, Danqiong, Li, Hui, Zolkiewska, Anna. The role of Delta-like 1 shedding in muscle cell self-renewal and differentiation. Journal of cell science, vol.121, no.22, 3815-3823.

  60. Segatto, Marco, Szokoll, Roberta, Fittipaldi, Raffaella, Bottino, Cinzia, Nevi, Lorenzo, Mamchaoui, Kamel, Filippakopoulos, Panagis, Caretti, Giuseppina. BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy. Nature communications, vol.11, no.1, 6108-.

  61. Movafagh, Shahrzad, Crook, Sean, Vo, Kim. Regulation of Hypoxia‐Inducible Factor‐1a by Reactive Oxygen Species : New Developments in an Old Debate. Journal of cellular biochemistry, vol.116, no.5, 696-703.

  62. Chandel, N. S., Maltepe, E., Goldwasser, E., Mathieu, C. E., Simon, M. C., Schumacker, P. T.. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proceedings of the National Academy of Sciences of the United States of America, vol.95, no.20, 11715-11720.

  63. Karar, J., Dolt, K.S., Mishra, M.K., Arif, E., Javed, S., Pasha, M.A.Q.. Expression and functional activity of pro-oxidants and antioxidants in murine heart exposed to acute hypobaric hypoxia. FEBS letters, vol.581, no.24, 4577-4582.

  64. Ono, Yusuke, Sensui, Hiroomi, Sakamoto, Yuzuru, Nagatomi, Ryoichi. Knockdown of hypoxia-inducible factor-1α by siRNA inhibits C2C12 myoblast differentiation. Journal of cellular biochemistry, vol.98, no.3, 642-649.

  65. Cicchillitti, Lucia, Di Stefano, Valeria, Isaia, Eleonora, Crimaldi, Luca, Fasanaro, Pasquale, Ambrosino, Valeria, Antonini, Annalisa, Capogrossi, Maurizio C., Gaetano, Carlo, Piaggio, Giulia, Martelli, Fabio. Hypoxia-inducible Factor 1-α Induces miR-210 in Normoxic Differentiating Myoblasts. The Journal of biological chemistry, vol.287, no.53, 44761-44771.

  66. Li, X., Zhu, L., Chen, X., Fan, M.. Effects of hypoxia on proliferation and differentiation of myoblasts. Medical hypotheses, vol.69, no.3, 629-636.

  67. Chang, Ya-Ju, Chen, Yun-Ju, Huang, Chia-Wei, Fan, Shih-Chen, Huang, Bu-Miin, Chang, Wen-Tsan, Tsai, Yau-Sheng, Su, Fong-Chin, Wu, Chia-Ching. Cyclic Stretch Facilitates Myogenesis in C2C12 Myoblasts and Rescues Thiazolidinedione-Inhibited Myotube Formation. Frontiers in bioengineering and biotechnology, vol.4, 27-.

  68. Morgan, Michael J, Liu, Zheng-gang. Crosstalk of reactive oxygen species and NF-κB signaling. Cell research, vol.21, no.1, 103-115.

  69. Lingappan, Krithika. NF-κB in oxidative stress. Current opinion in toxicology, vol.7, 81-86.

  70. KUMAR, ASHOK, MURPHY, RYAN, ROBINSON, PREMA, WEI, LEI, BORIE, ALADIN M.. Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac‐1 GTPase, andNF‐KBtranscription factor. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol.18, no.13, 1524-1535.

  71. CHANG, Hang, SHYU, Kou-Gi, WANG, Bao-Wei, KUAN, Peiliang. Regulation of hypoxia-inducible factor-1α by cyclical mechanical stretch in rat vascular smooth muscle cells. Clinical science, vol.105, no.4, 447-456.

  72. Lim, Chung S., Qiao, Xiaoying, Reslan, Ossama M., Xia, Yin, Raffetto, Joseph D., Paleolog, Ewa, Davies, Alun H., Khalil, Raouf A.. Prolonged mechanical stretch is associated with upregulation of hypoxia-inducible factors and reduced contraction in rat inferior vena cava. Journal of vascular surgery, vol.53, no.3, 764-773.

  73. Ko, Ung Hyun, Park, Sukhee, Bang, Hyunseung, Kim, Mina, Shin, Hyunjun, Shin, Jennifer H.. Promotion of Myogenic Maturation by Timely Application of Electric Field Along the Topographical Alignment. Tissue engineering. Part A, vol.24, no.9, 752-760.

  74. Sachs, Frederick. Stretch-Activated Ion Channels: What Are They?. Physiology, vol.25, no.1, 50-56.

  75. Bokhari, Bayan, Sharma, Sudha. Stress Marks on the Genome: Use or Lose?. International journal of molecular sciences, vol.20, no.2, 364-.

  76. Salmon, Tiffany B., Evert, Barbara A., Song, Binwei, Doetsch, Paul W.. Biological consequences of oxidative stress-induced DNA damage in Saccharomyces cerevisiae. Nucleic acids research, vol.32, no.12, 3712-3723.

  77. Kirito, Keita, Hu, Yongzhen, Komatsu, Norio. HIF-1 prevents the overproduction of mitochondrial ROS after cytokine stimulation through induction of PDK-1. Cell cycle, vol.8, no.17, 2844-2849.

  78. Lee, Ji-Won, Bae, Seong-Hui, Jeong, Joo-Won, Kim, Se-Hee, Kim, Kyu-Won. Hypoxia-inducible factor (HIF-1)α: its protein stability and biological functions. Experimental & molecular medicine : EMM, vol.36, no.1, 1-12.

  79. Zhao, Tao, Zhu, Yuxi, Morinibu, Akiyo, Kobayashi, Minoru, Shinomiya, Kazumi, Itasaka, Satoshi, Yoshimura, Michio, Guo, Guozheng, Hiraoka, Masahiro, Harada, Hiroshi. HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs. Scientific reports, vol.4, 3793-.

  80. Li, Hong-Sheng, Zhou, Yan-Ni, Li, Lu, Li, Sheng-Fu, Long, Dan, Chen, Xue-Lu, Zhang, Jia-Bi, Feng, Li, Li, You-Ping. HIF-1α protects against oxidative stress by directly targeting mitochondria. Redox biology, vol.25, 101109-.

  81. Faiss, Raphael, Léger, Bertrand, Vesin, Jean-Marc, Fournier, Pierre-Etienne, Eggel, Yan, Dériaz, Olivier, Millet, Grégoire P.. Significant Molecular and Systemic Adaptations after Repeated Sprint Training in Hypoxia. PloS one, vol.8, no.2, e56522-.

  82. Brocherie, F., Millet, G. P., D'Hulst, G., Van Thienen, R., Deldicque, L., Girard, O.. Repeated maximal‐intensity hypoxic exercise superimposed to hypoxic residence boosts skeletal muscle transcriptional responses in elite team‐sport athletes. Acta physiologica, vol.222, no.1, e12851-.

LOADING...

활용도 분석정보

상세보기
다운로드
내보내기

활용도 Top5 논문

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

관련 콘텐츠

유발과제정보 저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로