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Flavonoid Glycosides from Ulmus macrocarpa Inhibit Osteoclast Differentiation via the Downregulation of NFATc1 원문보기

ACS omega, v.7 no.6, 2022년, pp.4840 - 4849  

Wang, Weihong (Laboratory of Marine Drugs, School of Earth and Environmental Sciences , Seoul National University , Seoul 08826 , Korea) ,  Jeong, Chanhyeok (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences , Seoul National University , Seoul 08826 , Korea) ,  Lee, Yongjin (Department of Pharmacy , Sunchon National University , 315 Maegok-dong , Suncheon , Jeollanam-do 57922 , Korea) ,  Park, Chanyoon (Laboratory of Marine Drugs, School of Earth and Environmental Sciences , Seoul National University , Seoul 08826 , Korea) ,  Oh, Eunseok (Laboratory of Marine Drugs, School of Earth and Environmental Sciences , Seoul National University , Seoul 08826 , Korea) ,  Park, Kyu-Hyung (Laboratory of Marine Drugs, School of Earth and Environmental Sciences , Seoul National University , Seoul 08826 , Korea) ,  Cho, Youbin (Laboratory of Marine Drugs, School of Earth and Environmental Sciences , Seoul National Un) ,  Kang, Eunmo ,  Lee, JunI ,  Cho, Yeon-Jin ,  Park, Jung Han Yoon ,  Son, Young-Jin ,  Lee, Ki Won ,  Kang, Heonjoong

Abstract AI-Helper 아이콘AI-Helper

The aim of this study was to isolate and identify chemical components with osteoclast differentiation inhibitory activity from Ulmus macrocarpa Hance bark. Spectroscopic analyses, including nuclear magnetic resonance (NMR) and electronic circular dichroism (ECD), resulted in the unequivocal elucidat...

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