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Deficient neurotransmitter systems and synaptic function in frontotemporal lobar degeneration—Insights into disease mechanisms and current therapeutic approaches 원문보기

Molecular psychiatry, v.27 no.3, 2022년, pp.1300 - 1309  

Huber, Nadine (A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland) ,  Korhonen, Sonja (A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland) ,  Hoffmann, Dorit (A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland) ,  Leskelä, Stina (A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland) ,  Rostalski, Hannah (A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland) ,  Remes, Anne M. (Unit of Clinical Neuroscience, Neurology, University of Oulu, P. O. Box 8000, University of Oulu, FI-90014 Oulu, Finland) ,  Honkakoski, Paavo (School of Pharmacy, University of Eastern Finland, P.O. Box 1627, FI-70210 Kuopio, Finland) ,  Solje, Eino (Institute of Clinical Medicine—) ,  Haapasalo, Annakaisa (Neurology, University of Eastern Finland, P.O. Box 1627, FI-70210 Kuopio, Finland)

Abstract AI-Helper 아이콘AI-Helper

Frontotemporal lobar degeneration (FTLD) comprises a heterogenous group of fatal neurodegenerative diseases and, to date, no validated diagnostic or prognostic biomarkers or effective disease-modifying therapies exist for the different clinical or genetic subtypes of FTLD. Current treatment strategi...

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