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[해외논문] Emodin improves glucose metabolism and ovarian function in PCOS mice via the HMGB1/TLR4/NF-κB molecular pathway

Reproduction : the official journal of the Society for the Study of Fertility, v.166 no.5, 2023년, pp.323 - 336  

Otoo, Antonia (Department of Obstetrics and Gynecology, Women and Children's Hospital of Chongqing Medical University, Chongqing, People’s Republic of China) ,  Czika, Armin (Department of Reproductive Biology, Joint International Research Laboratory of Reproduction and Development, School of Public Health, Chongqing Medical University, Chongqing, People’s Republic of China) ,  Lamptey, Jones (Department of Reproductive Biology, Joint International Research Laboratory of Reproduction and Development, School of Public Health, Chongqing Medical University, Chongqing, People’s Republic of China) ,  Yang, Jun-Pu (Department of Reproductive Biology, Joint International Research Laboratory of Reproduction and Development, School of Public Health, Chongqing Medical University, Chongqing, People’s Republic of China) ,  Feng, Qian (Department of Gynecology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, People’s Republic of China) ,  Wang, Mei-Jiao (Department of Reproductive Biology, Joint International Research Laboratory of Reproduction and Development, School) ,  Wang, Ying-Xiong ,  Ding, Yu-Bin

Abstract AI-Helper 아이콘AI-Helper

In briefObese PCOS mice display metabolic and endocrine disorders that manifest as abnormal metabolism of glucose and dysfunctions in the reproductive system. This study demonstrates that emodin alleviates most of these conditions possibly via the HMGB1/TLR4/NF-kB pathway.AbstractPCOS is a reproduct...

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