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An in vitro alternative to the Draize eye-irritation test: Evaluation of the crystal violet staining method

Toxicology in vitro : an international journal published in association with BIBRA, v.5 no.2, 1991년, pp.139 - 143  

Itagaki, H. ,  Hagino, S. ,  Kato, S. ,  Kobayashi, T. ,  Umeda, M.

Abstract AI-Helper 아이콘AI-Helper

To evaluate a simple in vitro method as an alternative to the Draize eye-irritation test, 12 surfactants were tested by both of the above methods, and the correlation between the results was examined. The in vitro method used was the crystal violet staining method. HeLa cells or SIRC cells from rabb...

참고문헌 (25)

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  7. Journal of Toxicology-Cutaneous and Ocular Toxicology Jacaruso 4 49 1985 10.3109/15569528509068358 An in vitro method for assessing corneal opacification potential using a rabbit corneal cell line 

  8. Toxicology in Vitro Kato 2 125 1988 10.1016/0887-2333(88)90023-9 Liposomes as an in vitro model for predicting the eye irritancy of chemicals 

  9. Food and Chemical Toxicology Kemp 23 267 1985 10.1016/0278-6915(85)90027-4 Toxicity of commercial products on cells in suspension culture: a possible screen for the Draize eye irritation test 

  10. Cytobios Kemp 36 153 1983 A rapid cell culture technique for assessing the toxicity of detergent-based products in vitro as a possible screen for eye irritancy in vivo 

  11. Food and Chemical Toxicology Leighton 23 293 1985 10.1016/0278-6915(85)90031-6 The chick embryo in toxicology: an alternative to the rabbit eye 

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  17. Food and Chemical Toxicology North-Root 23 271 1985 10.1016/0278-6915(85)90028-6 Prediction of the eye irritation potential of shampoos using the in vitro SIRC cell toxicity test 

  18. Food and Chemical Toxicology Parish 23 215 1985 10.1016/0278-6915(85)90020-1 Ability of in vitro (corneal injury-eye organ-and chorioallantoic membrane) tests to represent histopathological features of acute eye inflammation 

  19. Food and Chemical Toxicology Price 23 313 1985 10.1016/0278-6915(85)90037-7 The in vitro assessment of eye irritancy using isolated eyes 

  20. Toxicology in Vitro Saotome 3 317 1989 10.1016/0887-2333(89)90039-8 Cytotoxicity test with simplified crystal violet staining method using microtitre plates and its application to injection drugs 

  21. International Journal of Cosmetic Science Scaife 4 179 1982 10.1111/j.1467-2494.1982.tb00313.x An investigation of detergent action on cells in vitro and possible correlations with in vivo data 

  22. Food and Chemical Toxicology Scaife 23 253 1985 10.1016/0278-6915(85)90025-0 An in vitro cytotoxicity test to predict the ocular irritation potential of detergents and detergent products 

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