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Toxicology letters, v.7 no.1, 1980년, pp.51 - 60
Eckhardt, K. (Zentrallaboratorium fur Mutagenitatsprufung der Deutschen Forschungsgemeinschaft, Breisacher Strosse 33, D-7800, Freiburg, F.R.G.) , King, M.-T. , Gocke, E. , Wild, D.
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Saccharin and contaminants of commercial Remsen-Fahlberg saccharin were studied for mutagenic potential with the use of the Salmonella/microsome test, Base-test in Drosophila melanogaster and micronucleus test in mice. In none of these tests were mutagenic effects of saccharin observed. Likewise, th...
J. Natl. Cancer Inst. Abe 58 1635 1977 10.1093/jnci/58.6.1635 Chromosome aberrations and sister chromatid exchanges in Chinese hamster cells exposed to various chemicals
Abrahamson Vol. 2 461 1971 The detection of mutations in Drosophila melanogaster
Mutation Res. Ames 31 347 1975 10.1016/0165-1161(75)90046-1 Methods for detecting carcinogens and mutagens with Salmonella/mammalian microsome mutagenicity test
Science Arnold 197 320 1977 10.1126/science.197.4301.320 Canadian saccharin study
Food Cosmet. Toxicol. Ashby 16 95 1977 10.1016/S0015-6264(78)80187-4 Saccharin: An epigenetic carcinogen/mutagen?
Science Batzinger 198 944 1977 10.1126/science.337489 Saccharin and other sweeteners: mutagenic properties
Science Bryan 168 1238 1970 10.1126/science.168.3936.1238 Production of urinary bladder carcinomas in mice by sodium saccharin
Cancer Res. Cohen 39 1207 1979 Promoting effect of saccharin and dl-tryptophan in urinary bladder carcinogenesis
1978
Mutation Res. Herbold 74 155 1980 10.1016/0165-1161(80)90246-0 On the mutagenicity of artificial sweeteners and their main impurities examined in the Salmonella/microsome test
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Mutation Res. Kramers 56 163 1977 10.1016/0027-5107(77)90205-6 Mutagenicity of saccharin in Drosophila: The possible role of contaminants
J. Environ. Pathol. Toxicol. Leonard 2 1047 1979 Mutagenicity test with saccharin in the male mouse
Chem.-Biol. Interact. Lutz 19 253 1977 10.1016/0009-2797(77)90036-9 Saccharin does not bind to DNA of liver or bladder in the rat
Arzneimittelforsch. Machemer 25 1889 1975 Method for testing mutagenic effects of chemicals on spermatogonia of the Chinese hamster. Results obtained with cyclophosphamide, saccharin and cyclamate
Mutation Res. Machemer 29 209 1975 10.1016/0027-5107(75)90134-7 Experiences with the dominant lethal test in female mice: effects of alkylating agents and artificial sweeteners on pre-ovulatory oocyte stages
Science Mondal 201 1141 1978 10.1126/science.684434 Enhancement of oncogenesis in C3H/10T 12 mouse embryo cell cultures by saccharin
Mutation Res. Moore 67 215 1979 10.1016/0165-1218(79)90015-6 Recombinogenicity and mutagenicity of saccharin in Saccharomyces cerevisiae
Science Moore 205 1007 1979 10.1126/science.382356 Genetic effects of impure and pure saccharin in yeast
Food Cosmet. Toxicol. Poncelet 17 229 1979 10.1016/0015-6264(79)90285-2 Absence of mutagenic activity in Salmonella typhimurium of some impurities found in saccharin
Toxicology Pool 11 95 1978 10.1016/S0300-483X(78)90639-X Non-mutagenicity of saccharine
Science Price 167 1131 1970 10.1126/science.167.3921.1131 Bladder tumors in rats fed cyclohexylamine or high doses of a mixture of cyclamate and saccharine
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Xenpbiotica Renwick 8 461 1978 10.3109/00498257809056148 The fate of saccharine impurities: the excretion and metabolism of toluene-2-sulphonamide in man and rat
Eur. J. Cancer Saxholm 15 509 1979 10.1016/0014-2964(79)90086-0 Carcinogenesis testing of saccharin. No transformation or increased sister chromatid exchange observed in two mammalian cell systems
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Z. Krebsforsch. Schmahl 91 19 1978 10.1007/BF00305968 Experiments on the carcinogenic effect of ortho-toluol-sulfonamid (OTS)
Schmid Vol. 4 31 1976 The micronucleus test for cytogenetic analysis
Dros. Inf. Serv. ？ram 44 120 1969 Mutagenic activity of saccharin
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Stavri 1974 American Chemical Society, 167th National Meeting Studies on water soluble impurities in commercial saccharins
J. Ass. Off. Anal. Chem. (AOAC) Stavri 58 427 1975 O-Toluenesulfonamide in saccharin preparations
J. Ass. Off. Agric. Chem. (AOAC) Stavri 59 1051 1976 Impurities in commercial saccharin, I. Impurities soluble in organic solvents
J. Environ. Pathol. Toxicol. Stoltz 1 139 1977 The mutagenicity of Saccharin impurities, I. Detection of mutagenic activity
Science Sweatman 205 1019 1979 10.1126/science.472722 Saccharin metabolism and tumorigenicity
Z. Elektrochem. Taufel 34 281 1928 Uber den Mechanismus der Hydrolyse von O-Benzoesauresulfimid (Saccharin) und von Sulfaminobenzoesaure
Food Cosmet. Toxicol. Van Went-de Vries 13 177 1975 10.1016/S0015-6264(75)80002-2 Saccharin: lack of chromosome-damaging activity in Chinese hamsters in vivo
Vogel Vol. 4 1492 1977 Identification of carcinogens by mutagen testing in Drosophila: The relative reliability for the kinds of genetic damage measured
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Science Wolff 200 543 1978 10.1126/science.644315 Saccharin-induced sister chromatid exchanges in Chinese hamster and human cells
Wurgler 335 1977 Drosophila as assay system for detecting genetic changes
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