[논문]Recent Developments, Characteristics, and Potential Applications of Electrochemical Biosensors

MEHRVAR, Mehrab; ABDI, Mustafe

doi:10.2116/analsci.20.1113

Recent Developments, Characteristics, and Potential Applications of Electrochemical Biosensors

Analytical sciences : The International Journal of the Japan Society for Analytical Chemistry, v.20 no.8, 2004년, pp.1113 - 1126

MEHRVAR, Mehrab (Department of Chemical Engineering, Ryerson University) , ABDI, Mustafe (Department of Chemical Engineering, Ryerson University)

Abstract ▼ AI-Helper

The objective of this study is to analyze the technical importance, performance, techniques, advantages, and disadvantages of the biosensors in general and of the electrochemical biosensors in particular. A product of reaction diffuses to the transducer in the first generation biosensors (based on Clark biosensors). The mediated biosensors or second generation biosensors use specific mediators between the reaction and the transducer to improve sensitivity. The second generation biosensors involve two steps: first, there is a redox reaction between enzyme and substrate that is reoxidized by the mediator, and eventually the mediator is oxidized by the electrode. No normal product or mediator diffusion is directly involved in the third generation biosensors, direct biosensors. Based on the type of transducer, current biosensors are divided into optical, mass, thermal, and electrochemical sensors. They are used in medical diagnostics, food quality controls, environmental monitoring, and other applications. These biosensors are also grouped under two broad categories of sensors: direct and indirect detection systems. Moreover, these systems could be further grouped into continuous or batch operation. Therefore, amperometric biosensors and their current applications are focused on more in detail since they are the most commonly used biosensors in monitoring and diagnosing tests in clinical analysis. Problems related to the commercialization of medical, environmental, and industrial biosensors as well as their performance characteristics, their competitiveness in comparison to the conventional analytical tools, and their costs determine the future development of these biosensors.

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Electrochim. Acta A K Abass 46 829 2001 10.1016/S0013-4686(00)00668-X A. K. Abass and J. P. Hart, Electrochim. Acta, 2001, 46, 829.

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Sens. Actuators, B A K Abass 41 169 1997 10.1016/S0925-4005(97)80291-2 A. K. Abass and J. P. Hart, Sens. Actuators, B, 1997, 41, 169.

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Sens. Actuators, B A K Abass 62 148 2000 10.1016/S0925-4005(99)00385-8 A. K. Abass, J. P. Hart, and D. Cowell, Sens. Actuators, B, 2000, 62, 148.

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Anal. Chim. Acta J C Vidal 385 213 1999 10.1016/S0003-2670(98)00838-1 J. C. Vidal, E. Garcia, and J. R. Castillo, Anal. Chim. Acta, 1999, 385, 213.

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표제어: PCR

동의어: Packet Collision Rate

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용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

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Recent Developments, Characteristics, and Potential Applications of Electrochemical Biosensors

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