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The Journal of dermatological treatment, v.16 no.2, 2005년, pp.87 - 94
Callaway, James , Schwab, Ursula , Harvima, Ilkka , Halonen, Pirjo , Mykkänen, Otto , Hyvönen, Pekka , Järvinen, Tomi
Background: Hempseed oil is a rich and balanced source of omega-6 and omega-3 polyunsaturated fatty acids (PUFAs). Anecdotal evidence indicated that dietary hempseed oil might be useful in treating symptoms of atopic dermatitis. Patients and methods: Dietary hempseed oil and olive oil were compared in a 20-week randomized, single-blind crossover study with atopic patients. Fatty acid profiles were measured in plasma triglyceride, cholesteryl and phospholipid fractions. A patient questionnaire provided additional information on skin dryness, itchiness and usage of dermal medications. Skin transepidermal water loss (TEWL) was also measured. Results: Levels of both essential fatty acids (EFAs), linoleic acid (18:2n6) and alpha-linolenic acid (18:3n3), and gamma-linolenic acid (GLA; 18:3n6) increased in all lipid fractions after hempseed oil, with no significant increases of arachidonic acid (20:4n6) in any lipid fractions after either oil. Intra-group TEWL values decreased (p?=?0.074), qualities of both skin dryness and itchiness improved (p?=?0.027) and dermal medication usage decreased (p?=?0.024) after hempseed oil intervention. Conclusions: Dietary hempseed oil caused significant changes in plasma fatty acid profiles and improved clinical symptoms of atopic dermatitis. It is suggested that these improvements resulted from the balanced and abundant supply of PUFAs in this hempseed oil.
10.1093/ajcn/71.1.367s Horrobin DF. Essential fatty acid metabolism and its modification in atopic eczema. Am J Clin Nutr. 2000;71:367-72S.
Proksch, Ehrhardt, Jensen, Jens-michael, Elias, Peter M. Skin lipids and epidermal differentiation in atopic dermatitis. Clinics in dermatology, vol.21, no.2, 134-144.
Zamaria, Nicolas. Alteration of polyunsaturated fatty acid status and metabolism in health and disease.. Reproduction, nutrition, development, vol.44, no.3, 273-282.
Manku, M.S., Horrobin, D.F., Morse, N., Kyte, V., Jenkins, K., Wright, S., Burton, J.L.. Reduced levels of prostaglandin precursors in the blood of atopic patients: Defective delta-6-desaturase function as a biochemical basis for atopy. Prostaglandins, leukotrienes, and medicine, vol.9, no.6, 615-628.
Drugs Exp Clin Res Bordoni A 291 14 1988
10.1159/000246224
HENZ,, JABLONSKA,, VAN DE KERKHOF,, STINGL,, BLASZCZYK,, VANDERVALK,, VEENHUIZEN,, MUGGLI,, RAEDERSTORFF,. Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema. British journal of dermatology : BJD, vol.140, no.4, 685-688.
Takwale, A. Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. BMJ : British medical journal, vol.327, no.7428, 1385-0.
van Gool, Christel JAW, Thijs, Carel, Henquet, Charles JM, van Houwelingen, Adriana C, Dagnelie, Pieter C, Schrander, Jaap, Menheere, Paul PCA, van den Brandt, Piet A. γ-Linolenic acid supplementation for prophylaxis of atopic dermatitis-a randomized controlled trial in infants at high familial risk. The American journal of clinical nutrition, vol.77, no.4, 943-951.
Wu, Dayong, Meydani, Mohsen, Leka, Lynette S, Nightingale, Zachary, Handelman, Garry J, Blumberg, Jeffrey B, Meydani, Simin Nikbin. Effect of dietary supplementation with black currant seed oil on the immune response of healthy elderly subjects. The American journal of clinical nutrition, vol.70, no.4, 536-543.
seed. J Int Hemp Assoc. Callaway JC 61 3 1997
Callaway, J. C.. Hempseed as a nutritional resource: An overview. Euphytica : Netherlands journal of plant breeding, vol.140, no.1, 65-72.
Kriese, U., Schumann, E., Weber, W.E., Beyer, M., Brühl, L., Matthäus, B.. Oil content, tocopherol composition and fatty acid patterns of the seeds of 51 Cannabis sativa L. genotypes. Euphytica : Netherlands journal of plant breeding, vol.137, no.3, 339-351.
Burr, George O., Burr, Mildred M.. A NEW DEFICIENCY DISEASE PRODUCED BY THE RIGID EXCLUSION OF FAT FROM THE DIET. The Journal of biological chemistry, vol.82, no.2, 345-367.
Burr, George O., Burr, Mildred M.. ON THE NATURE AND RÔLE OF THE FATTY ACIDS ESSENTIAL IN NUTRITION. The Journal of biological chemistry, vol.86, no.2, 587-621.
Excess linoleic acid and relative N-3 deficiency syndrome seen in Japan. Prog Lipid Res. Okuyama H 409 3 1997
Gerster H. Can adults adequately convert alpha-linolenic acid (18: 3n-3)to eicosapentanoic acid (20: 5n-3)and docosahex-anoic acid (22: 6n-3)?Int J Vit Nutr Res. 1988;68:159-73.
Kankaanpää, Pasi, Sütas, Yelda, Salminen, Seppo, Licbtenstein, Alice, Isolauri, Erika. Dietary fatty acids and allergy. Annals of medicine, vol.31, no.4, 282-287.
Simopoulos, A.P., Leaf, A., Salem Jr, N.. Workshop Statement on the Essentiality of and Recommended Dietary Intakes for Omega-6 and Omega-3 Fatty Acids. Prostaglandins, leukotrienes, and essential fatty acids, vol.63, no.3, 119-121.
Simopoulos, A.P. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie, vol.56, no.8, 365-379.
Thijs, C, van Houwelingen, A, Poorterman, I, Mordant, A, van den Brandt, P. Essential fatty acids in breast milk of atopic mothers: comparison with non-atopic mothers, and effect of borage oil supplementation. European journal of clinical nutrition, vol.54, no.3, 234-238.
Barre, D. Edward. Potential of Evening Primrose, Borage, Black Currant, and Fungal Oils in Human Health. Annals of nutrition & metabolism, vol.45, no.2, 47-57.
Van Gool, C.J.A.W., Zeegers, M.P.A., Thijs, C.. Oral essential fatty acid supplementation in atopic dermatitis—a meta-analysis of placebo-controlled trials. British journal of dermatology : BJD, vol.150, no.4, 728-740.
Plant resources of south-east Asia, no. 12, vol 1: de Padua LS 1999
10.1093/jat/25.8.691
Leson G, Pless P, Roulac JW, eds. Hemp foods & oils for health, 2nd edn. Sebastopol, California: Hemptech Ltd, 1999.
Hanfo¨ l: ein highlight fu¨r die ku¨ che? Forschungs Report Mattha¨us B 22 2 2002
10.1093/ajcn/70.3.560s Simopoulos AP. Essential fatty acids in health and chronic disease. Am J Clin Nutr. 1999;70:560-69S.
MANKU, M.S., HORROBIN, D.F., MORSE, N.L., WRIGHT, S., BURTON, J.L.. Essential fatty acids in the plasma phospholipids of patients with atopic eczema. British journal of dermatology : BJD, vol.110, no.6, 643-648.
Acta Derm Venereol Oliwiecki S 224 71 1991 10.2340/0001555571224228
Yamamoto, A., Serizawa, S., Ito, M., Sato, Y.. Stratum corneum lipid abnormalities in atopic dermatitis. Archives of dermatological research, vol.283, no.4, 219-223.
10.1111/1523-1747.ep12470233 Imokawa G, Abe A, Jin K, Higaki Y, Kawashima M, Hidano A. Decreased level of ceramide in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin? J Invest Dermatol. 1991;96:523-6.
Macheleidt, Oliver, Kaiser, Hans Wilhelm, Sandhoff, Konrad. Deficiency of Epidermal Protein-Bound &ohgr;-Hydroxyceramides in Atopic Dermatitis. The Journal of investigative dermatology, vol.119, no.1, 166-173.
10.1111/1523-1747.ep12348937 Murata Y, Ogata J, Higaki Y, Kawashima M, Yada Y, Higuchi K, et al. Abnormal expression of sphingomyelin acylase in atopic dermatitis: an etiologic factor for ceramide deficiency? J Invest Dermatol. 1996;106:1242-9.
Ohnishi, Yoshinori, Okino, Nozomu, Ito, Makoto, Imayama, Shuhei. Ceramidase Activity in Bacterial Skin Flora as a Possible Cause of Ceramide Deficiency in Atopic Dermatitis. Clinical and diagnostic laboratory immunology, vol.6, no.1, 101-104.
Vidal, C., Armisén, M., Domínguez-Santalla, M. J., Gude, F., Lojo, S., González-Quintela, A.. Influence of Alcohol Consumption on Serum Immunoglobulin E Levels in Atopic and Nonatopic Adults. Alcoholism: clinical and experimental research, vol.26, no.1, 59-64.
Heck, Diane E, Gerecke, Donald R, Vetrano, Anna M, Laskin, Jeffrey D. Solar ultraviolet radiation as a trigger of cell signal transduction. Toxicology and applied pharmacology, vol.195, no.3, 288-297.
ABE, TAKASHI, MAYUZUMI, JUNKO, KIKUCHI, NORIKO, ARAI, SEIICHI. Seasonal variations in skin temperature, skin pH, evaporative water loss and skin surface lipid values on human skin.. Chemical & pharmaceutical bulletin, vol.28, no.2, 387-392.
Rogers, J., Harding, C., Mayo, A., Banks, J., Rawlings, A.. Stratum corneum lipids: the effect of ageing and the seasons. Archives of dermatological research, vol.288, no.12, 765-770.
Uter, Wolfgang, Hegewald, Janice, Pfahlberg, Annette, Pirker, Claudia, Frosch, Peter J., Gefeller, Olaf. The association between ambient air conditions (temperature and absolute humidity), irritant sodium lauryl sulfate patch test reactions and patch test reactivity to standard allergens. Contact dermatitis, vol.49, no.2, 97-102.
Arerugi Sakai K 37 43 1994
Rastas M, Seppa¨nen R, Knuts L-R, et al. Nutrient composi-tion of foods. Turku. Finland: Social Insurance Institution, 1997.
Acta Derm Venereol Hanifin JM
Nuutinen, Jouni, Alanen, Esko, Autio, Pekka, Lahtinen, Marjo-Riitta, Harvima, Ilkka, Lahtinen, Tapani. A closed unventilated chamber for the measurement of transepidermal water loss. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Soci, vol.9, no.2, 85-89.
10.1016/S0022-2275(20)41345-8 A°gren JJ, Julkunen A, Penttila¨ I. Rapid separation of serum lipids for fatty acid analysis by a single aminopropyl column. J Lipid Res. 1992;33:1871-76.
Tsoureli-Nikita, Evridiki, Hercogova, Jana, Lotti, Torello, Menchini, Giovanni. Evaluation of dietary intake of vitamin E in the treatment of atopic dermatitis: a study of the clinical course and evaluation of the immunoglobulin E serum levels. International journal of dermatology, vol.41, no.3, 146-150.
Briganti, S, Picardo, M. Antioxidant activity, lipid peroxidation and skin diseases. What's new. Journal of the European Academy of Dermatology and Venereology : JEADV, vol.17, no.6, 663-669.
10.1080/000155501750208092
Ziboh, VA, Fletcher, MP. Dose-response effects of dietary γ-linolenic acid-enriched oils on human polymorphonuclear-neutrophil biosynthesis of leukotriene B4. The American journal of clinical nutrition, vol.55, no.1, 39-45.
10.1007/978-1-59259-709-3_13 Ziboh VA. Nutritional modulation of inflammation by polyunsaturated fatty acids/eicosanoids. In: Gershwin ME, German JB, Keen CL, editors. Nutrition and immunology: principles and practice. Totowa, NJ: Humana Press, 2000: 157-67.
James, Michael J, Ursin, Virginia M, Cleland, Leslie G. Metabolism of stearidonic acid in human subjects: comparison with the metabolism of other n−3 fatty acids. The American journal of clinical nutrition, vol.77, no.5, 1140-1145.
Yehuda, Shlomo, Rabinovitz, Sharon, L. Carasso, Ralph, I. Mostofsky, David. The role of polyunsaturated fatty acids in restoring the aging neuronal membrane. Neurobiology of aging, vol.23, no.5, 843-853.
Sugarman, Jeffrey L, Fluhr, Joachim W, Fowler, Ashley J, Bruckner, Thomas, Diepgen, Thomas L, Williams, Mary L. The objective severity assessment of atopic dermatitis score: an objective measure using permeability barrier function and stratum corneum hydration with computer-assisted estimates for extent of disease.. Archives of dermatology, vol.139, no.11, 1417-1422.
10.1080/00015559850135788 di Nardo A, Wertz P, Giannetti A, Seidenari S. Ceramide and cholesterol composition of the skin of patients with atopic dermatitis. Acta Derm Venereol. 1998;78:27-30.
Harbige, Laurence S.. Dietaryn-6 andn-3 fatty acids in immunity and autoimmune disease. Proceedings of the Nutrition Society, vol.57, no.4, 555-562.
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