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Genotoxicity of three‐carbon compounds evaluated in the SCE test in vitro

Environmental mutagenesis, v.9 no.4, 1987년, pp.401 - 410  

von der Hude, Wilhelm ,  Scheutwinkel, Michael ,  Gramlich, Ulrike ,  Fibler, Brigitte ,  Basler, Armin

Abstract AI-Helper 아이콘AI-Helper

AbstractThree‐carbon chemicals (chlorinated and nonchlorinated, saturated and unsaturated, hydroxy‐ and oxo‐hydrocarbons) were assayed for genotoxicity. The sister chromatid exchange test in vitro served as the test system. Without S9 mix, the nonchlorinated solvents 1‐pr...

참고문헌 (22)

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  2. Basler, A., v. d. Hude, W., Scheutwinkel-Reich, M.. Formaldehyde-induced sister chromatid exchanges in vitro and the influence of the exogenous metabolizing systems S9 mix and primary rat hepatocytes. Archives of toxicology : Archiv für Toxikologie, vol.58, no.1, 10-13.

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  6. Haseman, J. K., Crawford, D. D., Huff, J. E., Boorman, G. A., McConnell, E. E.. Results from 86 two-year carcinogenicity studies conducted by the national toxicology program. Journal of toxicology and environmental health, vol.14, no.5, 621-639.

  7. Gann Konishi Y 922 71 1980 Forestomach tumors induced by orally administered epichlorohydrin in male Wistar rats 

  8. Kringstad, Knut P., Ljungquist, Pierre O., De Sousa, Filipe., Stroemberg, Lars M.. Stability of 2-chloropropenal and some other mutagens formed in the chlorination of softwood kraft pulp. Environmental science & technology, vol.17, no.8, 468-471.

  9. J Natl Cancer Inst Laskin S 751 65 1980 10.1093/jnci/65.4.751 Inhalation carcinogenicity of epichlorohydrin in non inbred Spraque‐Dawley rats 

  10. Latt, S.A., Allen, J., Bloom, S.E., Carrano, A., Falke, E., Kram, D., Schneider, E., Schreck, R., Tice, R., Whitfield, B., Wolff, S.. Sister-chromatid exchanges: A report of the GENE-TOX program. Mutation research. Reviews in genetic toxicology, vol.87, no.1, 17-62.

  11. Lowry, OliverH., Rosebrough, NiraJ., Farr, A. Lewis, Randall, RoseJ.. PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT. The Journal of biological chemistry, vol.193, no.1, 265-275.

  12. Maron, Dorothy, Katzenellenbogen, John, Ames, Bruce N.. Compatibility of organic solvents with the Salmonella/microsome test. Mutation research. Genetic toxicology testing, vol.88, no.4, 343-350.

  13. Nakamura, A., Noriyuki, T., Kojima, S., Kaniwa; Taro Kawamura, M.-a.. The mutagenicity of halogenated alkanols and their phosphoric acid esters for Salmonella typhimurium. Mutation research. Genetic toxicology testing, vol.66, no.4, 373-380.

  14. Neudecker, T., Lutz, D., Eder, E., Henschler, D.. Structure-activity relationship in halogen and alkyl substituted allyl and allylic compounds: Correlation of alkylating and mutagenic properties. Biochemical pharmacology, vol.29, no.19, 2611-2617.

  15. Newsome, William H., Panopio, Luz G.. A method for the determination of 1,3-dichloropropene, 1,2-dibromoethane, and 1,2-dibromo-3-chloropropane in food crops. Journal of agricultural and food chemistry, vol.25, no.5, 998-1000.

  16. Pfeiffer, E.H., Dunkelberg, H.. Mutagenicity of ethylene oxide and propylene oxide and of the glycols and halohydrins formed from them during the fumigation of foodstuffs. Food and cosmetics toxicology, vol.18, no.2, 115-118.

  17. Scudamore, K. A., Heuser, S. G.. Ethylene oxide and its persistent reaction products in wheat flour and other commodities: Residues from fumigation or sterilisation, and effects of processing. Pesticide science, vol.2, no.2, 80-91.

  18. J Toxicol Environm Health Stolzenberg SJ 1151 5 1979 10.1080/15287397909529820 Mutagenicity of halogenated and oxygenated 3‐carbon compounds 

  19. Stolzenberg, S. J., Hine, C. H.. Mutagenicity of 2‐ and 3‐carbon halogenated compounds in the salmonella/mammalian‐microsome test. Environmental mutagenesis, vol.2, no.1, 59-66.

  20. J Natl Cancer Inst van Duuren L 1433 63 1979 Carcinogenicity of halogenated olefinic and aliphatic hydrocarbons in mice 

  21. Velíšek, Jan, Davidek, Jiří, Hajšlová, Jana, Kubelka, Vladislav, Janíček, Gustav, Mánková, Blanka. Chlorohydrins in protein hydrolysates. Zeitschrift für Lebensmittel-Untersuchung und -Forschung, vol.167, no.4, 241-244.

  22. White, A.D.. In vitro induction of SCE in human lymphocytes by epichlorohydrin with and without metabolic activation. Mutation research. Genetic toxicology testing, vol.78, no.2, 171-176.

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