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β-Adrenergic modulation of muscarinic cholinergic receptor expression and function in developing heart
American journal of physiology. Regulatory, integrative and comparative physiology, v.282 no.5 = v.51 no.5, 2002년, pp.R1356 - R1363
Garofolo, M. C. (Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710) , Seidler, F. J. (Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710) , Auman, J. T. (Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710) , Slotkin, T. A. (Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710)
Abstract
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Imbalances of β-adrenoceptor (β-AR) and muscarinic ACh receptor (mAChR) input are thought to underlie perinatal cardiovascular abnormalities in conditions such as sudden infant death syndrome. Administration of isoproterenol, a β1/β2-AR agonist, to neonatal rats on postnatal days...
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