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Biological & pharmaceutical bulletin, v.30 no.6, 2007년, pp.1147 - 1149
Horiuchi, Kumiko (Department of Molecular Microbiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University) , Shiota, Sumiko (Laboratory of Pathogenic Microbiology, Department of Biological Pharmacy, School of Pharmacy, Shujitsu University) , Hatano, Tsutomu (Department of Pharmacognosy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University) , Yoshida, Takashi (Department of Pharmacognosy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University) , Kuroda, Teruo (Department of Molecular Microbiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University) , Tsuchiya, Tomofusa (Department of Molecular Microbiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University)
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An extract from Salvia officinalis (Sage) leaves showed antimicrobial activity against vancomycin-resistant enterococci (VRE). We isolated the effective compound and identified it as oleanolic acid, a triterpenoid. We also tested antimicrobial activity of similar triterpenoids, ursolic acid, uvaol, ...
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