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Quantification of reduced glutathione by HPLC-UV in erythrocytes of hemodialysis patients

Biomedical chromatography : BMC, v.22 no.5, 2008년, pp.460 - 468  

Garcia, Solange Cristina (Laboratory of Toxicology (LATOX), Department of Clinical and Toxicology Analysis, Center of Healthy Sciences, Federal University of Santa Maria, 97105-900, Santa Maria, RS, Brazil) ,  Schott, Karen (Laboratory of Toxicology (LATOX), Department of Clinical and Toxicology Analysis, Center of Healthy Sciences, Federal University of Santa Maria, 97105-900, Santa Maria, RS, Brazil) ,  Charão, Mariele (Laboratory of Toxicology (LATOX), Department of Clinical and Toxicology Analysis, Center of Healthy Sciences, Federal University of Santa Maria, 97105-900, Santa Maria, RS, Brazil) ,  Moro, Angela (Laboratory of Toxicology (LATOX), Department of Clinical and Toxicology Analysis, Center of Healthy Sciences, Federal University of Santa Maria, 97105-900, Santa Maria, RS, Brazil) ,  Bulcão, Rachel (Laboratory of Toxicology (LATOX), Department of Clinical and Toxicology Analysis, Center of Healthy Sciences, Federal University of Santa Maria, 97105-900, Santa Maria, RS, Brazil) ,  Grotto, Denise (Laboratory of Toxicology (LATOX), Department of Clinical and Toxicology Analysis, Center o) ,  Valentini, Juliana ,  Bohrer, Denise ,  Cardoso, Simone ,  Pomblum, Valdeci

Abstract AI-Helper 아이콘AI-Helper

Reduced glutathione (GSH) is a well-known multifunctional antioxidant. Its depletion is linked to a number of pathologies, such as renal insufficiency. Feasible methodologies in clinical chemistry are vital. Therefore a methodology for GSH quantification was optimized and validated by HPLC-UV. Impor...

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