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NTIS 바로가기Drug metabolism and disposition: the biological fate of chemicals, v.37 no.2, 2009년, pp.359 - 365
Shukla, Suneet , Robey, Robert W. , Bates, Susan E. , Ambudkar, Suresh V.
Sunitinib malate (Sutent, SU11248) is a small-molecule receptor tyrosine kinase inhibitor that inhibits cellular signaling of multiple targets such as the platelet-derived growth factor receptors and the vascular endothelial growth factor receptors and is used in the treatment of renal cell carcinom...
Bello, Carlo L., Sherman, Laurie, Zhou, Jihao, Verkh, Lev, Smeraglia, John, Mount, Janessa, Klamerus, Karen J.. Effect of food on the pharmacokinetics of sunitinib malate (SU11248), a multi-targeted receptor tyrosine kinase inhibitor: results from a phase I study in healthy subjects. Anti-cancer drugs, vol.17, no.3, 353-358.
Breedveld, Pauline, Pluim, Dick, Cipriani, Greta, Wielinga, Peter, van Tellingen, Olaf, Schinkel, Alfred H., Schellens, Jan H.M.. The Effect of Bcrp1 (Abcg2) on the In vivo Pharmacokinetics and Brain Penetration of Imatinib Mesylate (Gleevec): Implications for the Use of Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors to Enable the Brain Penetration of Imatinib in Patients. Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.65, no.7, 2577-2582.
Brendel, C, Scharenberg, C, Dohse, M, Robey, R W, Bates, S E, Shukla, S, Ambudkar, S V, Wang, Y, Wennemuth, G, Burchert, A, Boudriot, U, Neubauer, A. Imatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, vol.21, no.6, 1267-1275.
Cancer Biol Ther 4 747 2005 10.4161/cbt.4.7.1826
Cascorbi, Ingolf. Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs. Pharmacology & therapeutics, vol.112, no.2, 457-473.
Chow, Laura Q.M., Eckhardt, S. Gail. Sunitinib: From Rational Design to Clinical Efficacy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol.25, no.7, 884-896.
Druley, T. E., Stein, W. D., Roninson, I. B.. Analysis of MDR1 P-Glycoprotein Conformational Changes in Permeabilized Cells Using Differential Immunoreactivity. Biochemistry, vol.40, no.14, 4312-4322.
Elkind, N. Barry, Szentpétery, Zsófia, Apáti, Ágota, Özvegy-Laczka, Csilla, Várady, György, Ujhelly, Olga, Szabó, Katalin, Homolya, László, Váradi, András, Buday, László, Kéri, György, Német, Katalin, Sarkadi, Balázs. Multidrug Transporter ABCG2 Prevents Tumor Cell Death Induced by the Epidermal Growth Factor Receptor Inhibitor Iressa (ZD1839, Gefitinib). Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.65, no.5, 1770-1777.
Cancer Res 61 739 2001
Faivre, Sandrine, Delbaldo, Catherine, Vera, Karina, Robert, Caroline, Lozahic, Stéphanie, Lassau, Nathalie, Bello, Carlo, Deprimo, Samuel, Brega, Nicoletta, Massimini, Giorgio, Armand, Jean-Pierre, Scigalla, Paul, Raymond, Eric. Safety, Pharmacokinetic, and Antitumor Activity of SU11248, a Novel Oral Multitarget Tyrosine Kinase Inhibitor, in Patients With Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol.24, no.1, 25-35.
Ferrao, Petranel T., Frost, Michelle J., Siah, Shoo-Peng, Ashman, Leonie K.. Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro. Blood, vol.102, no.13, 4499-4503.
Goodman, Vicki L., Rock, Edwin P., Dagher, Ramzi, Ramchandani, Roshni P., Abraham, Sophia, Gobburu, Jogarao V.S., Booth, Brian P., Verbois, S. Leigh, Morse, David E., Liang, Cheng Yi, Chidambaram, Nallaperumal, Jiang, Janet X., Tang, Shenghui, Mahjoob, Kooros, Justice, Robert, Pazdur, Richard. Approval Summary: Sunitinib for the Treatment of Imatinib Refractory or Intolerant Gastrointestinal Stromal Tumors and Advanced Renal Cell Carcinoma. Clinical Cancer research : an official journal of the American Association for Cancer Research, vol.13, no.5, 1367-1373.
Hanahan, Douglas, Weinberg, Robert A. The Hallmarks of Cancer. Cell, vol.100, no.1, 57-70.
Biochim Biophys Acta 1587 318 2002 10.1016/S0925-4439(02)00095-9
Illmer, T, Schaich, M, Platzbecker, U, Freiberg-Richter, J, Oelschlägel, U, von Bonin, M, Pursche, S, Bergemann, T, Ehninger, G, Schleyer, E. P-glycoprotein-mediated drug efflux is a resistance mechanism of chronic myelogenous leukemia cells to treatment with imatinib mesylate. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, vol.18, no.3, 401-408.
Leggas, Markos, Panetta, John C., Zhuang, Yanli, Schuetz, John D., Johnston, Brad, Bai, Feng, Sorrentino, Brian, Zhou, Sheng, Houghton, Peter J., Stewart, Clinton F.. Gefitinib Modulates the Function of Multiple ATP-Binding Cassette Transporters In vivo. Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.66, no.9, 4802-4807.
Lemos, C, Jansen, G, Peters, G J. Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors. The British journal of cancer, vol.98, no.5, 857-862.
Liu, Weiguo, Baer, Maria R., Bowman, Mary Jo, Pera, Paula, Zheng, Xiang, Morgan, Janet, Pandey, Ravindra A., Oseroff, Allan R.. The Tyrosine Kinase Inhibitor Imatinib Mesylate Enhances the Efficacy of Photodynamic Therapy by Inhibiting ABCG2. Clinical Cancer research : an official journal of the American Association for Cancer Research, vol.13, no.8, 2463-2470.
Blood 96 1070 2000 10.1182/blood.V96.3.1070
Mechetner, Eugene B., Schott, Brigitte, Morse, Brian S., Stein, Wilfred D., Druley, Todd, Davis, Kenneth A., Tsuruo, Takashi, Roninson, Igor B.. P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity. Proceedings of the National Academy of Sciences of the United States of America, vol.94, no.24, 12908-12913.
Muller, M., Yong, M., Peng, X.-H., Petre, B., Arora, S., Ambudkar, S. V.. Evidence for the Role of Glycosylation in Accessibility of the Extracellular Domains of Human MRP1 (ABCC1). Biochemistry, vol.41, no.31, 10123-10132.
Özvegy-Laczka, Csilla, Cserepes, Judit, Elkind, N. Barry, Sarkadi, Balázs. Tyrosine kinase inhibitor resistance in cancer: role of ABC multidrug transporters. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, vol.8, no.1, 15-26.
Özvegy-Laczka, Csilla, Hegedűs, Tamás, Várady, György, Ujhelly, Olga, Schuetz, John D., Váradi, András, Kéri, György, Őrfi, László, Német, Katalin, Sarkadi, Balázs. High-Affinity Interaction of Tyrosine Kinase Inhibitors with the ABCG2 Multidrug Transporter. Molecular pharmacology, vol.65, no.6, 1485-1495.
Eur J Cancer 38 Suppl 5 S3 2002
Polli, Joseph W., Humphreys, Joan E., Harmon, Kelly A., Castellino, Stephen, O'Mara, Michael J., Olson, Katie L., John-Williams, Lisa St., Koch, Kevin M., Serabjit-Singh, Cosette J.. The Role of Efflux and Uptake Transporters inN-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions. Drug metabolism and disposition: the biological fate of chemicals, vol.36, no.4, 695-701.
Robey, R W, Honjo, Y, Morisaki, K, Nadjem, T A, Runge, S, Risbood, M, Poruchynsky, M S, Bates, S E. Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity. The British journal of cancer, vol.89, no.10, 1971-1978.
Clin Cancer Res 7 145 2001
Robey, Robert W., Shukla, Suneet, Steadman, Kenneth, Obrzut, Tomasz, Finley, Elizabeth M., Ambudkar, Suresh V., Bates, Susan E.. Inhibition of ABCG2-mediated transport by protein kinase inhibitors with a bisindolylmaleimide or indolocarbazole structure. Molecular cancer therapeutics, vol.6, no.6, 1877-1885.
Robey, Robert W., Steadman, Kenneth, Polgar, Orsolya, Morisaki, Kuniaki, Blayney, Margaret, Mistry, Prakash, Bates, Susan E.. Pheophorbide a Is a Specific Probe for ABCG2 Function and Inhibition. Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.64, no.4, 1242-1246.
Rock, Edwin P., Goodman, Vicki, Jiang, Janet X., Mahjoob, Kooros, Verbois, S. Leigh, Morse, David, Dagher, Ramzi, Justice, Robert, Pazdur, Richard. Food and Drug Administration Drug Approval Summary: Sunitinib Malate for the Treatment of Gastrointestinal Stromal Tumor and Advanced Renal Cell Carcinoma. The oncologist, vol.12, no.1, 107-113.
Sarkadi, Balázs, Homolya, László, Szakács, Gergely, Váradi, András. Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System. Physiological reviews, vol.86, no.4, 1179-1236.
Sauna, Zuben E., Ambudkar, Suresh V.. Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein. Proceedings of the National Academy of Sciences of the United States of America, vol.97, no.6, 2515-2520.
Sauna, Zuben E., Peng, Xiang-Hong, Nandigama, Krishnamachary, Tekle, Samrawit, Ambudkar, Suresh V.. The Molecular Basis of the Action of Disulfiram as a Modulator of the Multidrug Resistance-Linked ATP Binding Cassette Transporters MDR1 (ABCB1) and MRP1 (ABCC1). Molecular pharmacology, vol.65, no.3, 675-684.
Shi, Zhi, Peng, Xing-Xiang, Kim, In-Wha, Shukla, Suneet, Si, Qiu-Sheng, Robey, Robert W., Bates, Susan E., Shen, Tong, Ashby Jr., Charles R., Fu, Li-Wu, Ambudkar, Suresh V., Chen, Zhe-Sheng. Erlotinib (Tarceva, OSI-774) Antagonizes ATP-Binding Cassette Subfamily B Member 1 and ATP-Binding Cassette Subfamily G Member 2-Mediated Drug Resistance. Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.67, no.22, 11012-11020.
Shukla, S., Robey, R. W., Bates, S. E., Ambudkar, S. V.. The Calcium Channel Blockers, 1,4-Dihydropyridines, Are Substrates of the Multidrug Resistance-Linked ABC Drug Transporter, ABCG2. Biochemistry, vol.45, no.29, 8940-8951.
Shukla, S, Sauna, Z E, Ambudkar, S V. Evidence for the interaction of imatinib at the transport-substrate site(s) of the multidrug-resistance-linked ABC drug transporters ABCB1 (P-glycoprotein) and ABCG2. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, vol.22, no.2, 445-447.
Shukla, Suneet, Wu, Chung-Pu, Ambudkar, Suresh V. Development of inhibitors of ATP-binding cassette drug transporters - present status and challenges. Expert opinion on drug metabolism & toxicology, vol.4, no.2, 205-223.
Skehan, P., Storeng, R., Scudiero, D., Monks, A., McMahon, J., Vistica, D., Warren, J. T., Bokesch, H., Kenney, S., Boyd, M. R.. New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening. Journal of the National Cancer Institute: JNCI, vol.82, no.13, 1107-1112.
Stewart, Clinton F., Leggas, Markos, Schuetz, John D., Panetta, John C., Cheshire, Pamela J., Peterson, Jennifer, Daw, Najat, Jenkins III, Jesse J., Gilbertson, Richard, Germain, Glen S., Harwood, Franklin C., Houghton, Peter J.. Gefitinib Enhances the Antitumor Activity and Oral Bioavailability of Irinotecan in Mice. Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.64, no.20, 7491-7499.
Widmer, N, Rumpold, H, Untergasser, G, Fayet, A, Buclin, T, Decosterd, L A. Resistance reversal by RNAi silencing of MDR1 in CML cells associated with increase in imatinib intracellular levels. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, vol.21, no.7, 1561-1562.
Wu, Chung-Pu, Shukla, Suneet, Calcagno, Anna Maria, Hall, Matthew D., Gottesman, Michael M., Ambudkar, Suresh V.. Evidence for dual mode of action of a thiosemicarbazone, NSC73306: a potent substrate of the multidrug resistance-linked ABCG2 transporter. Molecular cancer therapeutics, vol.6, no.12, 3287-3296.
Yang, Chih-Hsin, Huang, Ching-Ju, Yang, Chao-Shun, Chu, Yu-Chuan, Cheng, Ann-Lii, Whang-Peng, Jacqueline, Yang, Pan-Chyr. Gefitinib Reverses Chemotherapy Resistance in Gefitinib-Insensitive Multidrug Resistant Cancer Cells Expressing ATP-Binding Cassette Family Protein. Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.65, no.15, 6943-6949.
Zong, Y, Zhou, S, Sorrentino, B P. Loss of P-glycoprotein expression in hematopoietic stem cells does not improve responses to imatinib in a murine model of chronic myelogenous leukemia. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, vol.19, no.9, 1590-1596.
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