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Sunitinib (Sutent, SU11248), a Small-Molecule Receptor Tyrosine Kinase Inhibitor, Blocks Function of the ATP-Binding Cassette (ABC) Transporters P-Glycoprotein (ABCB1) and ABCG2 원문보기

Drug metabolism and disposition: the biological fate of chemicals, v.37 no.2, 2009년, pp.359 - 365  

Shukla, Suneet ,  Robey, Robert W. ,  Bates, Susan E. ,  Ambudkar, Suresh V.

Abstract AI-Helper 아이콘AI-Helper

Sunitinib malate (Sutent, SU11248) is a small-molecule receptor tyrosine kinase inhibitor that inhibits cellular signaling of multiple targets such as the platelet-derived growth factor receptors and the vascular endothelial growth factor receptors and is used in the treatment of renal cell carcinom...

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