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Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells

Arthritis and rheumatism, v.60 no.4, 2009년, pp.1006 - 1019  

González, Manuel A. (Cellerix SA, Tres Cantos, and Fundació) ,  Gonzalez-Rey, Elena (n Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain) ,  Rico, Laura (University of Seville, Seville, Spain) ,  Büscher, Dirk (Cellerix SA, Tres Cantos, Spain) ,  Delgado, Mario (Cellerix SA, Tres Cantos, Spain)

Abstract AI-Helper 아이콘AI-Helper

ObjectiveRheumatoid arthritis (RA) is a chronic autoimmune disease caused by loss of immunologic self tolerance and characterized by chronic joint inflammation. Adult mesenchymal stem cells (MSCs) were recently found to suppress effector T cell responses and to have beneficial effects in various imm...

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