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Alteration of growth-phase-dependent protein regulation by afurmutation inHelicobacter pylori 원문보기

FEMS microbiology letters, v.294 no.1, 2009년, pp.102 - 110  

Choi, Young Wook ,  Park, Shin Ae ,  Lee, Hyang Woo ,  Lee, Na Gyong

Abstract AI-Helper 아이콘AI-Helper

The ferric-uptake regulator (Fur) protein is an Fe(2+)-dependent transcriptional repressor. To clarify the global regulation of Helicobacter pylori proteins by Fur according to the growth phase, we compared the proteome profiles of H. pylori 26695 and its isogenic fur mutant, harvested during in vit...

참고문헌 (24)

  1. Alamuri P , Mehta N , Burk A & Maier RJ (2006) Regulation of the Helicobacter pylori Fe–S cluster synthesis protein NifS by iron, oxidative stress conditions, and fur. J Bacteriol 188: 5325–5330. 

  2. Bachman MA & Swanson MS (2001) RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase. Mol Microbiol 40: 1201–1214. 

  3. Baichoo N & Helmann JD (2002) Recognition of DNA by Fur: a reinterpretation of the Fur box consensus sequence. J Bacteriol 184: 5826–5832. 

  4. 10.1099/00221287-144-9-2505 Bereswill S , Waidner U , Odenbreit S , Lichte F , Fassbinder F , Bode G & Kist M (1998) Structural, functional and mutational analysis of the pfr gene encoding a ferritin from Helicobacter pylori. Microbiology 144: 2505–2516. 

  5. 10.1128/IAI.70.2.606-611.2002 Bijlsma JJ , Waidner B , van Vliet AH , Hughes NJ , Hag S , Bereswill S , Kelly DJ , Vandenbroucke-Grauls CM , Kist M & Kusters JG (2002) The Helicobacter pylori homologue of the ferric uptake regulator is involved in acid resistance. Infect Immun 70: 606–611. 

  6. Blaser MJ & Atherton JC (2004) Helicobacter pylori persistence: biology and disease. J Clin Invest 113: 321–333. 

  7. 10.1002/1522-2683(200204)23:7/8<1161::AID-ELPS1161>3.0.CO;2-7 Cho MJ , Jeon BS , Park JW et al. (2002) Identifying the major proteome components of Helicobacter pylori strain 26695. Electrophoresis 23: 1161–1173. 

  8. 10.1002/pmic.200700689 Choi YW , Park SA , Lee HW , Kim DS & Lee NG (2008) Analysis of growth phase-dependent proteome profiles reveals differential regulation of mRNA and protein in Helicobacter pylori. Proteomics 8: 2665–2675. 

  9. 10.1128/.61.3.319-336.1997 Crosa JH (1997) Signal transduction and transcriptional and posttranscriptional control of iron-regulated genes in bacteria. Microbiol Mol Biol R 61: 319–336. 

  10. 10.1128/JB.00120-06 Danielli A , Roncarati D , Delany I , Chiarini V , Rappuoli R & Scarlato V (2006) In vivo dissection of the Helicobacter pylori Fur regulatory circuit by genome-wide location analysis. J Bacteriol 188: 4654–4662. 

  11. 10.1046/j.1365-2958.2001.02696.x Delany I , Spohn G , Rappuoli R & Scarlato V (2001) The Fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pylori. Mol Microbiol 42: 1297–1309. 

  12. Dubrac S & Touati D (2000) Fur positive regulation of iron superoxide dismutase in Escherichia coli: functional analysis of the sodB promoter. J Bacteriol 182: 3802–3808. 

  13. 10.1099/mic.0.27404-0 Ernst FD , Bereswill S , Waidner B , Stoof J , Mader U , Kusters JG , Kuipers EJ , Kist M , van Vliet AH & Homuth G (2005) Transcriptional profiling of Helicobacter pylori Fur- and iron-regulated gene expression. Microbiology 151: 533–546. 

  14. 10.1111/j.1365-2958.2005.04525.x Gaynor EC , Wells DH , MacKichan JK & Falkow S (2005) The Campylobacter jejuni stringent response controls specific stress survival and virulence-associated phenotypes. Mol Microbiol 56: 8–27. 

  15. Hall HK & Foster JW (1996) The role of fur in the acid tolerance response of Salmonella typhimurium is physiologically and genetically separable from its role in iron acquisition. J Bacteriol 178: 5683–5691. 

  16. 10.1128/jb.178.14.3996-4003.1996 Hassett DJ , Sokol PA , Howell ML , Ma JF , Schweizer HT , Ochsner U & Vasil ML (1996) Ferric uptake regulator (Fur) mutants of Pseudomonas aeruginosa demonstrate defective siderophore-mediated iron uptake, altered aerobic growth, and decreased superoxide dismutase and catalase activities. J Bacteriol 178: 3996–4003. 

  17. 10.1128/JB.183.2.468-475.2001 Horsburgh MJ , Ingham E & Foster SJ (2001) In Staphylococcus aureus, fur is an interactive regulator with PerR, contributes to virulence, and is necessary for oxidative stress resistance through positive regulation of catalase and iron homeostasis. J Bacteriol 183: 468–475. 

  18. 10.1046/j.1365-2958.2000.01896.x Jungblut PR , Bumann D , Haas G , Zimmy-Arndt U , Holland P , Lamer S , Siejak F , Aebischer A & Meyer TF (2000) Comparative proteome analysis of Helicobacter pylori. Mol Microbiol 36: 710–725. 

  19. 10.1002/pmic.200300740 Lee HW , Choe YH , Kim DK , Jung SY & Lee NG (2004) Proteomic analysis of a ferric uptake regulator mutant of Helicobacter pylori: regulation of Helicobacter pylori gene expression by ferric uptake regulator and iron. Proteomics 4: 2014–2027. 

  20. 10.1128/IAI.71.11.6510-6525.2003 Merrell DS , Thompson LJ , Kim CC , Mitchell H , Tompkins LS , Lee A & Falkow S (2003) Growth phase-dependent response of Helicobacter pylori to iron starvation. Infect Immun 71: 6510–6525. 

  21. Ochsner UA & Vasil ML (1996) Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes. P Natl Acad Sci USA 93: 4409–4414. 

  22. 10.1128/IAI.71.5.2643-2655.2003 Thompson LJ , Merrell DS , Neilan BA , Mitchell H , Lee S & Falkow S (2003) Gene expression profiling of Helicobacter pylori reveals a growth-phase-dependent switch in virulence gene expression. Infect Immun 71: 2643–2655. 

  23. 10.1046/j.1523-5378.2002.00088.x van Vliet AH , Stoof J , Vlasblom R et al. (2002) The role of the Ferric Uptake Regulator (Fur) in regulation of Helicobacter pylori iron uptake. Helicobacter 7: 237–244. 

  24. 10.1074/jbc.M207542200 van Vliet AH , Stoof J , Poppelaars SW , Bereswill S , Homuth G , Kist M , Kuipers EJ & Kusters JG (2003) Differential regulation of amidase- and formamidase-mediated ammonia production by the Helicobacter pylori fur repressor. J Biol Chem 278: 9052–9057. 

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